The invention relates to the technical field of anticoccidial drugs, in particular to an anticoccidial preparation containing nicarbazin and a preparation method of the anticoccidial preparation. The anticoccidial preparation containing nicarbazin comprises the following raw materials in parts by
mass: 3-7 parts of nicarbazin, 6-14 parts of
monensin, 5-10 parts of
mesoporous silica, 1-3 parts of
chitosan, 1-2 parts of
soybean lecithin, 0.1-0.5 part of carboxyl-terminated polyamidoamine, 1-2 parts of an emulsifier, 1-2 parts of a film-forming agent, 1-3 parts of a dispersant and 20-30 parts of
vegetable oil. According to the present invention, the
bioavailability is effectively improved, the problem of overhigh or overlow local
drug concentration is overcome, the poultry can be prevented from being easily poisoned after
ingestion, the
treatment effect can be improved, the
coccidiosis prevention and
treatment effect is significant, the poultry growth is effectively promoted, the production cost is effectively reduced, and the
batch production and the large-area promotion are easily achieved.