Pharmaceutical composition for preventing and treating chicken coccidiosis and application thereof

Abstract

The invention provides a pharmaceutical composition for preventing and treating chicken coccidiosis and an application thereof. The pharmaceutical composition contains lactobacillus plantarum P8 and chlorogenic acid, wherein the biological preservation number of the lactobacillus plantarum P8 is CGMCC No. 6312. According to the invention, immune imbalance and intestinal oxidative damage of broilerchickens caused by coccidiosis infection can be relieved; the content of anti-inflammatory factors can be significantly improved, and the content of pro-inflammatory factors can be reduced, so the body immunity tends to be normal; meanwhile, the pharmaceutical composition provided by the invention can also relieve intestinal barrier damage, repair intestinal structures and enhance the resistanceof intestinal mucosa, is beneficial for intestinal health, can completely or partially replace chemically synthesized anticoccidial drugs and antibiotic products, has no drug residues and pollution, and is green, safe and environmentally-friendly.

Description

technical field [0001] The invention belongs to the technical field of livestock and poultry medicines, and in particular relates to a pharmaceutical composition for preventing and treating coccidiosis in chickens and its application, in particular to an anti-coccidiosis treatment with Lactobacillus plantarum P8 and chlorogenic acid as active ingredients drug. Background technique [0002] Chicken coccidiosis is a kind of intestinal parasitic protozoan disease that is prevalent globally, has no seasonality, high morbidity and high mortality, and causes economic losses of several billion US dollars in the world every year. It is caused by one or several AIDS Merle coccidia parasitizes the epithelial cells of the intestinal tract of chickens. Infected chickens often have damaged intestinal mucosal epithelium, poor intestinal digestion and absorption, and even death. The mortality rate is as high as 80%, which seriously endangers the development of the poultry industry. [000...

AI Technical Summary

Problems solved by technology

By searching the existing technologies at home and abroad, there is no literature report that Lactobacillus plantarum P8 has biological activity against coccidio

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