Preparation method of compound anticoccidial medicine sulfachloropyrazine sodium solution
A technology of sulfachlorpyrazine sodium and high-efficiency anti-coccidia, which is applied in the direction of drug combination, anti-infective drugs, drug delivery, etc., can solve the problem that the compound sulfachlorpyrazine sodium solution has not been reported or approved for application, and the patent search has not found problems. Patent protection and other issues to achieve stable product quality, convenient drug administration, and simple production process
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[0012] Accurately weigh 25L of dimethyl sulfoxide, 40L of N-methylpyrrolidone and 15kg of sulfachlorpyrazine sodium, pour them into the liquid mixing tank and stir at room temperature until dissolved, add 3kg of ditrimethoprim dissolved in a cosolvent, and finally Adjust the pH value (6.5-8.0) with triethanolamine, and adjust the volume to 100L with N-methylpyrrolidone. The medicinal solution is then filtered through a 0.45 μm microporous filter element, and then sterilized at 100°C for 30 minutes.
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