Preparation method of compound anticoccidial medicine sulfachloropyrazine sodium solution

Abstract

The invention relates to a preparation method of a compound high-efficiency anticoccidial medicine sulfachloropyrazine sodium and diaveridine solution. The solution is provided mainly for overcoming defects such as mixing difficulty, inconvenient dosing, inaccurate dose, and the like of existing powders. The solution comprises main components of: main medicines of sulfachloropyrazine sodium and diaveridine, and auxiliary materials of dimethyl sulfoxide, N-methylpyrrolidone, a cosolvent, and triethanolamine. A preparation process provided by the invention comprises the steps that: dimethyl sulfoxide, N-methylpyrrolidone, and sulfachloropyrazine sodium are dissolved in a liquid blending tank; diaveridine well dissolved by the cosolvent is added; and triethanolamine with a formulated dose is added. The method has the advantages of simple production process, stable product quality, simple feeding method, and accurate dose.

Description

Technical field [0001] The present invention involves a compound efficient anti -pyramidsulfine sodium chipine sodium and di methaxiline piopyrazide solution. Background technique [0002] Sulfidazine sodium sodium, chemical name N- (5-chloro-3-pyrium) -4-sodium salt compounds of sodium salt salt, molecular weight 324.72, molecular type C 10 H 8 CLN 4 NaO 2 S · H 2 O, white or pale yellow powder; tasteless.Solk in water or methanol, slightly soluble in ethanol or acetone, and insoluble in methane.Dimetoxyraine, chemical name is 5- (3,4-di oxygenyl) -2,4-piperidine dinamine, molecular weight 260.29, molecular type C 13 H 16 N 4 O 2 , White or slightly yellow crystalline powder; almost odorless.Extremely dissolved in methane, insoluble in water, ethanol, or ether; dissolved in hydrochloric acid, slightly soluble in dilute hydrochloric acid.Lipid water distribution coefficient logp 3 = 1. [0003] Parasitic diseases that are often seen in chickens and are very serious in chickens.At...

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Problems solved by technology

[0008] (3) In the state of disease or stress, chickens often have reduced feed intake or no food, but generally drink water normally, so the premix will not work well exert its medicinal effect

[0009]Compound sulfachlorpyrazine sodium solution has not been reported or approved for application at home and abroad, and no patent protection has been found in patent searches