Building method and application of oral microbial community detection model

A technology of oral microorganisms and detection models, applied in special data processing applications, instruments, electrical digital data processing, etc., can solve the problems of limiting clinical transformation and application prospects, optimization and perfection, etc., to achieve simple detection objects, strong detection capabilities, easy-to-handle effects

Active Publication Date: 2016-12-07
QINGDAO INST OF BIOENERGY & BIOPROCESS TECH CHINESE ACADEMY OF SCI +1
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Problems solved by technology

Therefore, most diagnostic methods and models stop at simple modeling after the screening of biological factors, without further optimization and improvement of their methods and models, which limits their clinical transformation and application prospects

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  • Building method and application of oral microbial community detection model
  • Building method and application of oral microbial community detection model
  • Building method and application of oral microbial community detection model

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Embodiment Construction

[0034] The present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments.

[0035] The present invention uses oral dental plaque and saliva microbial flora to construct and optimize the detection model of children's oral state as an example ( figure 1 ), including the following:

[0036] (1) Collect the clinical information of children's oral health status (Table 1):

[0037] A follow-up survey was conducted on the oral health of full-time children in Guangzhou Nanfang Chinese-English Kindergarten. The oral health was checked every six months, three times a year, and then checked at intervals of one year. ) index, and according to the purpose of this study, children with the following three types of oral health change characteristics were selected for this research: ①Healthy control group (H2H group): 17 children with oral caries kept healthy all the time; ②Caries occurrence group (H2C group): 21 children whose oral...

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Abstract

The invention relates to the field of microbial detection models, in particular to a building method and an application of an oral microbial community detection model. The method comprises the following steps of data collection, data screening, data deletion, model preliminary building and model optimization. According to the method and the application, a model object can be simply acquired and processed, the noninvasiveness is realized, the cost is low, and the object detection is relatively simple; and the modeling optimization method is easy in operation, the data processing is efficient, and the detection capability is good.

Description

technical field [0001] The invention relates to the field of microbial detection models, in particular to a method for constructing an oral microbial community detection model and its application. Background technique [0002] As the main carrier of acquired endowments, a large number of symbiotic flora parasitic on the human body are closely related to the health of the human body. It is currently believed that symbiotic microorganisms can be used as the second genome of the human body, and the sum of their genetic information is called the microbiome, which endows humans with complex individual characteristics that do not depend on their own evolution. Therefore, on the basis of a comprehensive understanding of the symbiotic flora of the human body, it is possible to deeply reveal its impact on human health or disease status, so as to establish the relationship between the existence and changes of the microbial flora and specific diseases. [0003] The oral system is a tr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/00
Inventor 滕飞杨芳黄适凌均棨徐健
Owner QINGDAO INST OF BIOENERGY & BIOPROCESS TECH CHINESE ACADEMY OF SCI
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