Fluorescent cyanoacrylate materials

A cyanoacrylate, fluorescent group technology, applied in the direction of luminescent materials, bulk chemical production, bandages, etc., can solve the problems of inability to effectively observe the bonding effect of materials, observe the condition of materials, and difficult to observe and distinguish

Inactive Publication Date: 2018-12-11
INST OF PHARMACOLOGY & TOXICOLOGY ACAD OF MILITARY MEDICAL SCI P L A
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to the colorless and transparent characteristics of cyanoacrylate polymers, it is difficult to observe and identify these materials with the naked eye after use.
In addition, although the FDA has only approved the use of such materials on the human body surface, the research will involve the use of cyanoacrylate materials in animals. In this case, it is difficult to directly observe the material after use. status
For example, when cyanoacrylate materials are applied to the adhesion of animal intestinal tissue, the abdominal cavity of the tested animal needs to be opened after the operation, otherwise it is impossible to effectively observe the adhesion effect of the material on the tissue, and whether there is detachment, displacement, etc. Happening

Method used

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  • Fluorescent cyanoacrylate materials
  • Fluorescent cyanoacrylate materials
  • Fluorescent cyanoacrylate materials

Examples

Experimental program
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Embodiment Construction

[0124] Embodiments of the present invention will be described in detail below in conjunction with the drawings and examples, but those skilled in the art will understand that the following drawings and examples are only for illustrating the present invention, and should not be considered as limiting the scope of the present invention. Those who do not indicate the specific conditions in the accompanying drawings and the examples are carried out according to the conventional conditions or the conditions suggested by the manufacturer. The reagents or instruments used were not indicated by the manufacturer, and they were all commercially available conventional products. All anhydrous solvents used are commercially available.

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Abstract

The invention relates to a cyanoacrylate material capable of producing fluorescence, in particular to a method for preparing a cyanoacrylate polymer containing fluorophores. The method is implemented according to a route shown in the specifications. The invention further relates to a monomer 1, a polymer 1, a polymer 2, a polymer 1', a polymer 2', an adhesive containing the compounds or the polymers, a dressing containing the compounds, the polymers or the adhesive as well as an application of the compounds or the polymers in preparation of the cyanoacrylate polymer containing the fluorophores.

Description

technical field [0001] The invention relates to the fields of biomedicine and materials, in particular to a method for preparing cyanoacrylate polymers with fluorescent groups, the compounds and polymers involved in the method, and the adhesives comprising the compounds or polymers Agents, dressings comprising the compounds, polymers or adhesives, and uses of the compounds or polymers for the preparation of cyanoacrylate polymers with fluorescent groups. Background technique [0002] Cyanoacrylates were first synthesized by German scientists in 1949. Such compounds are colorless transparent liquids at room temperature, 2 - , OH - ) in the presence of anionic polymerization easily, resulting in a colorless and transparent solid polymer. Cyanoacrylate compounds show good adhesion to plastics, ceramics, wood, glass and other materials, as well as human or animal tissues such as skin, blood vessels, muscles, and mucous membranes. For example, 502 glue, which is common in dai...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): C08F222/32C08F8/34C08F8/00C07C271/16C07C255/23C09K11/06A61L15/42A61L15/24A61L15/20A61L24/04A61L24/00
CPCA61L15/20A61L15/24A61L15/42A61L24/00A61L24/001A61L24/046C07C255/23C07C271/16C08F8/00C08F8/34C08F222/32C08F222/324C08F2800/20C08F2810/50C09K11/06C09K2211/145C08L35/04C08F222/328Y02P20/55
Inventor刘克良徐亮张涛汤永嘉高琴
OwnerINST OF PHARMACOLOGY & TOXICOLOGY ACAD OF MILITARY MEDICAL SCI P L A