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A traditional Chinese medicine composition for treating fatty liver and its preparation method and application

A composition and fatty liver technology, which can be used in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve problems such as liver function damage, achieve the goal of reducing content, improving liver biochemical functions, and reducing liver fat deposition Effect

Active Publication Date: 2019-02-22
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the above-mentioned treatment methods are only aimed at the primary underlying disease or preventing the progression of fatty liver, and have not yet achieved satisfactory clinical efficacy. Long-term use has hepatotoxicity, which can aggravate liver function damage

Method used

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  • A traditional Chinese medicine composition for treating fatty liver and its preparation method and application
  • A traditional Chinese medicine composition for treating fatty liver and its preparation method and application
  • A traditional Chinese medicine composition for treating fatty liver and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1 Chinese medicine composition of the present invention

[0037] 1. Raw materials

[0038] 15 parts of kudzu root, 10 parts of astragalus, 10 parts of Morus alba, 8 parts of Alisma, 10 parts of hawthorn, 10 parts of cassia seed, 12 parts of turmeric, and 10 parts of Jiaogulan.

[0039] 2. Preparation method

[0040] Take kudzu root, astragalus root, mulberry bark, Alisma, hawthorn, cassia seed, turmeric, and gynostemma, and add water 10 times the sum of the weight of each raw material to the multi-functional extraction tank for extraction. The extraction time is 2 hours, and the extraction is 3 times. The extracts were combined, filtered through gauze, and the filtrate was concentrated in a vacuum concentrator until the density was 1.10 when concentrated to 30°C. The above concentrate is dried in a spray drier and then pulverized to obtain a traditional Chinese medicine composition.

Embodiment 2

[0041] Embodiment 2 Chinese medicine composition of the present invention

[0042] 1. Raw materials

[0043] 6 parts of kudzu root, 12 parts of astragalus, 8 parts of Morus alba, 10 parts of Alisma, 7 parts of hawthorn, 12 parts of cassia seed, 6 parts of turmeric, and 12 parts of Jiaogulan.

[0044] 2. Preparation method

[0045] Take kudzu root, astragalus root, mulberry root, Alisma, hawthorn, cassia seed, turmeric, and gynostemma, mix them, and add 60% ethanol 10 times the weight of each raw material to the multifunctional extraction tank for extraction. The extraction time is 1.5h. Extract twice, combine the extracts, filter with gauze, and concentrate the filtrate in a vacuum concentrator until it is concentrated to 30°C, and the density is 1.25. The above concentrate is dried in a belt drier and pulverized to obtain a traditional Chinese medicine composition.

Embodiment 3

[0046] Embodiment 3 Chinese medicine composition of the present invention

[0047] 1. Raw materials

[0048] 24 parts of kudzu root, 8 parts of astragalus, 12 parts of Morus alba, 6 parts of Alisma, 13 parts of hawthorn, 8 parts of cassia seed, 18 parts of turmeric, and 8 parts of Jiaogulan.

[0049] 2. The preparation method is the same as in Example 1.

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Abstract

The invention relates to the technical field of traditional Chinese medicines and discloses a traditional Chinese medicine composition, and a preparation method and an application thereof. The traditional Chinese medicine composition is prepared from radix puerariae, radix astragali, cortex mori, rhizoma alismatis, fructus crataegi, semen cassiae, radix curcumae and gynostemma pentaphylla. According to the composition, through compounding, the effects of the radix puerariae, the radix astragali, the cortex mori, the rhizoma alismatis, the fructus crataegi, the semen cassiae, the radix curcumae and the gynostemma pentaphylla in the aspect of treating fatty liver are mutually enhanced, and a good compounding effect is displayed; and an experiment shows that the traditional Chinese medicine composition can remarkably reduce fat deposition in the liver and remarkably improve a biochemical function of the liver, and has a remarkable effect in the aspect of treating or preventing the fatty liver.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition and its preparation method and application. Background technique [0002] Fatty liver disease (FLD) refers to a pathological state in which fat metabolism in the liver is impaired due to various reasons, and the dynamic balance of lipids is out of balance, resulting in excessive fat accumulation in liver cells. Clinically, according to whether there is excessive alcohol intake, fatty liver is divided into two categories: alcoholic fatty liver disease (AFLD) and non-alcoholic fatty liver disease (NAFLD). [0003] Alcoholic fatty liver, predisposing factors mainly in alcohol consumption and drinking habits, gender and genetic and individual differences. The drinking threshold for alcoholic liver disease is 30g / d. The higher the alcohol consumption, the greater the risk of alcoholic liver disease. Drinking alcohol ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P1/16
CPCA61K36/424A61K36/481A61K36/482A61K36/488A61K36/605A61K36/734A61K36/884A61K36/9066A61K2236/33A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 萧伟商晶江益平韩兆忠王贵阳李英吴云王振中周习
Owner JIANGSU KANION PHARMA CO LTD
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