Composition for preventing or treating menopausal disorders, containing tetragonia tetragonoides (pall.) kuntze extract

A technology of composition and extract, which is applied in the direction of medical preparations containing active ingredients, food science, plant raw materials, etc., can solve the problems of undisclosed effects of menopausal disorders, and achieve the effect of improving glucose metabolism disorders

Inactive Publication Date: 2018-08-03
KOREA INST OF ORIENTAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, it has been disclosed (Korean Patent No. 10-0483183) that the extract of Apricot apricot is used to treat liver diseases due to its activity of inhibiting extinct cells, but the effect of the apricot on menopausal disorders has not been disclosed

Method used

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  • Composition for preventing or treating menopausal disorders, containing tetragonia tetragonoides (pall.) kuntze extract
  • Composition for preventing or treating menopausal disorders, containing tetragonia tetragonoides (pall.) kuntze extract
  • Composition for preventing or treating menopausal disorders, containing tetragonia tetragonoides (pall.) kuntze extract

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0060] Preparation example 1. prepare the apricot extract

[0061] In order to prepare the apricot extract, the apricot collected in Jeju Island, South Korea was used, water or ethanol 10 times the sampling amount of the apricot was added, and then treated at a temperature of 70° C. for 12 hours to obtain the apricot extract. The apricot extract was filtered through a 0.4 μm filter, concentrated and freeze-dried using a rotary evaporator, thereby preparing the apricot extract.

experiment example 1

[0062] Experimental example 1. Preparation of animal samples for inducing menopause

[0063] In order to confirm the effect of the apricot extract prepared according to the preparation example 1 on menopausal disorders, a mouse animal sample that induced menopause was prepared.

[0064] The menopause was induced by removing the ovaries of the experimental rats, and the weight of the uterus and the serum value of 17β-estradiol, which is a kind of female hormone, were measured in order to confirm whether the experimental rats were induced to menopause. Specifically, after sacrificing the experimental rats, the uterus was removed and the body weight was measured, and the concentration of serum 17β-estradiol was measured by a radioimmunoassay kit. The results of the measurements as described above are shown in Table 1 below.

[0065] Table 1 Evaluating whether to induce menopause in ovariectomized experimental rats

[0066]

[0067] (All values ​​are expressed as mean ± SD. T...

Embodiment 1

[0070] Example 1. Confirmation of the obesity-improving effect of the apricot extract

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PUM

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Abstract

The present invention relates to: a pharmaceutical composition for preventing or treating menopausal disorders, containing a Tetragonia tetragonoides (Pall.) Kuntze extract or a fraction thereof; a method for preventing or treating menopausal disorders, comprising a step of administering the pharmaceutical composition; and a food composition containing the extract or a fraction thereof. The Tetragonia tetragonoides (Pall.) Kuntze extract of the present invention shows effects of alleviating obesity, which is representative of glucose metabolism disorders and lipid metabolism disorders, osteoporosis, which is representative of bone homeostasis disorders, and flushing, which is representative of energy metabolism disorders, and thus the extract can be used in food, a medicine and the like soas to prevent, alleviate or treat menopausal disorders.

Description

technical field [0001] The present invention relates to a composition for preventing or treating menopausal disorders containing Tetragonia tetragonoides (Pall.) Kuntze extract, in particular, to a composition containing the Tetragonia tetragonoides (Pall.) Kuntze extract or its extract. A pharmaceutical composition for preventing or treating menopausal disorders, a method for preventing or treating menopausal disorders comprising the step of taking the pharmaceutical composition, and a food composition containing the extract or its extract. Background technique [0002] The period of about one year after menopause is called the menopausal transition period, more commonly called menopause, and generally this time is 4 to 7 years on average. According to the Korean Menopausal Society, about 89% of Korean women over the age of 50 suffer from menopausal symptoms. Menopause is characterized by disturbances in glucose metabolism, lipid metabolism, bone homeostasis, and energy me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/36
CPCA61K36/185A61K2236/00A23L33/105A23V2002/00
Inventor 高柄燮朴宣珉李惠园陆真雅朴仁实金秀兰
Owner KOREA INST OF ORIENTAL MEDICINE
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