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Duodenal adenocarcinoma prognostic prediction system based on COX proportional hazard model

A duodenal adenocarcinoma, proportional hazards model technology, applied in the field of duodenal adenocarcinoma prognosis prediction system, can solve problems such as the duodenal adenocarcinoma prognosis prediction system has not yet been established, and achieve the effect of improving survival prognosis

Inactive Publication Date: 2018-08-10
ZHEJIANG UNIV
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Problems solved by technology

However, a postoperative prognosis prediction system for duodenal adenocarcinoma based on clinical features has not yet been established.

Method used

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  • Duodenal adenocarcinoma prognostic prediction system based on COX proportional hazard model
  • Duodenal adenocarcinoma prognostic prediction system based on COX proportional hazard model
  • Duodenal adenocarcinoma prognostic prediction system based on COX proportional hazard model

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Embodiment 1

[0095] This embodiment provides a technical solution based on the prognosis prediction system for patients with duodenal adenocarcinoma. The system provided by this embodiment can be implemented by a system device, which is integrated in a computer device. The method specifically includes The following steps:

[0096] data collection

[0097] Select the data source: select the SEER (Surveillance, Epidemiology, and End Results database) database as the data source. 698 patients with duodenal adenocarcinoma met the inclusion criteria and became the data set for constructing the prognosis prediction system in this paper.

[0098] From January 2006 to December 2012, the inventor retrospectively collected patients with duodenal adenocarcinoma who received surgical treatment in the Second Affiliated Hospital of Zhejiang University and Run Run Shaw Hospital, and used data similar to the SEER data set. Group and exclusion criteria were screened, and a total of 137 patients with duod...

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Abstract

The invention provides a duodenal adenocarcinoma patient postoperative prognostic prediction system based on a COX proportional hazard model. The system comprises a memory, an information processing module and a prediction result displayer. The information processing module is configured for performing the following calculation and comparing the calculation result with the duodenal adenocarcinomapostoperative prognostic prediction index pre-stored in the memory and outputting the prediction result to the prediction result displayer: (I) the score of each risk factor is calculated according tothe following relation; (II) summation of all the scores obtained in the (I) is performed and the total score Z is calculated; and (III) the three-year survival rate (Y3) or the five-year survival rate (Y5) of the patient is calculated according to the following relation.

Description

technical field [0001] The invention relates to a prognostic prediction system for duodenal adenocarcinoma based on a COX proportional hazard model. Background technique [0002] Primary duodenal adenocarcinoma is a rare but extremely aggressive malignancy accounting for less than 0.5% of gastrointestinal malignancies and about 10% of small bowel neoplasms, although the duodenum accounts for less than 10% of the length of the small intestine 45%. Due to the involvement of organs and tissues such as the gallbladder, pancreas, portal vein, and mesenteric vessels, the particularity of the anatomical site of duodenal adenocarcinoma and the non-specificity of clinical symptoms often lead to delayed diagnosis and poor prognosis. At present, the TNM staging is mainly used to evaluate the prognosis of duodenal adenocarcinoma clinically. TNM staging mainly examines the depth of tumor invasion to duodenal adenocarcinoma, lymph node metastasis, and distant metastasis. However, it is ...

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Application Information

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IPC IPC(8): G16H50/30
CPCG16H50/30
Inventor 韩卫东蒋苏静谢建胜赵荣杰潘宏铭
Owner ZHEJIANG UNIV
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