A kind of acne-removing conditioning water
A technology of anti-acne and composition, which is applied in skin care preparations, pharmaceutical formulas, cosmetic preparations, etc., and can solve problems such as affecting appearance and difficulty in treatment
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Embodiment 1~9
[0029] Examples 1 to 9 are examples of the acne conditioning water of the present invention, and the formulations of the acne conditioned water described in Examples 1 to 6 are shown in Table 1. Examples 7 to 9 The formulation of acne conditioning water is shown in Table 2. In Examples 1 to 9, the weight of each component in acne composition A is: 15 parts of Danshen root extraction, 3 clove bud extracts, 2 of the astragalus extract, 2 parts of the root extraction, licorice 1 part of the root extract and 1 part of the snow grass; the weight of each component in acne composition B is: 3 parts of white flower snake extract, 3 copies of honeysuckle extract and small fruit soap seed extract 1 Part.
[0030] Embodiment 1 to 9 The preparation method of acne conditioning water includes the following steps:
[0031] S1, water, glycerol, hydroxyethylurea, sodium hyaluronate, guava extract, nicotinamide, hydroxybenzyl and propylene glycol are stirred to 85 ° C, heat insulation for 20 minute...
Embodiment 10
[0043] Product Safety Evaluation (Human Skin Plastic Experiment)
[0044] First, the test product: Example 1 ~ 9, the acne conditioned water prepared by the proportion 1, 2
[0045] Number of subjects: 110 people, women
[0046] Age: between 12 ~ 30 years old
[0047] Health Status: Subjects are healthy, no history of skin disease, in line with subject volunteers.
[0048] Group: 11 groups, 10 people per group, with an average age of 25 ± 2 years.
[0049] Second, the spotted method: use a qualified spot test to close the spotted spot experiment, and the subject is about 0.020g ~ 0.025g to the speculator, and the external special tape is attached to the back of the subject, 24 After the hour, removing the test material, removed the skin reaction after 0.5, 6, 12, 24, 48 hours, recorded the results in the skin reaction grading standard in the "Cosmetics Health Specification".
[0050] Third, the experimental results: the results of the human skin spots showed that the subjects of e...
Embodiment 11
[0052] Antibacterial effect test
[0053] First, test materials
[0054] 1. Test strain: Acne acne (ATCC6919).
[0055] 2, test sample: according to S1, S2, S3, S4, S5, S6, S7, S8, D1, D2 sample, 4 ° C, S1, S2, S3, S4, S5, S6, S7, S8, D1 D2 correspond to the ratio of the acne component in Examples 1 to 8 and the contrast 1, 2, respectively.
[0056] 3, medium: acne-acne culture medium, adjusted pH of 6.6 ~ 7.0. Agaric 15g / L is added therein.
[0057] Second, the test method
[0058] 1. Preparation and inoculation of bacterial suspensions: 0.1 ml of the freezer in Hollycene hauspine was 0.1 ml of 5 ml of acne acne hydrazine liquid medium, and 2D was cultured in anaerobic conditions at 37 ° C, which was an experimental fungicus suspension.
[0059] 2, the preparation of the drug: S1, S2, S3, S4, S5, S6, S7, S8, D1, D2 are respectively diluted with physiological saline as 0.1%, and then diluted separately. The first test gradient dilution concentration was 100% (sample stock soluti...
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