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Application of 2-cyclic amino fatty diacid derivatives in the preparation of animal feed additives

A technology of cyclic amino fats and derivatives, which is applied in the field of application of 2-cyclic amino fatty diacid derivatives in the preparation of animal feed additives, and can solve the problems that the use of compounds is rarely reported

Active Publication Date: 2022-06-24
GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] 2-Cyclic amino fatty diacids are a class of compounds produced by the Michael addition reaction of α,β-unsaturated diacids and cyclic ammonia. From 1962 to 2016, researches have reported the synthesis, purification and Structural characterization and other methods, but the use of such compounds is rarely reported

Method used

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  • Application of 2-cyclic amino fatty diacid derivatives in the preparation of animal feed additives
  • Application of 2-cyclic amino fatty diacid derivatives in the preparation of animal feed additives
  • Application of 2-cyclic amino fatty diacid derivatives in the preparation of animal feed additives

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0151] Example 1 The effect of 2-cyclic amino fatty acid derivatives on the performance of pigs

[0152] 300 65-day-old "Du Dachang" ternary hybrid lean piglets with similar body weight were randomly divided into 10 treatment groups with 3 replicates in each group, 10 pigs in each replicate, half male and female. The pigpen and utensils were disinfected before the test. During the test period, the pigs were kept in separate pens under the same feeding and management conditions. During the experiment, the experimental pigs had free access to food and water, and were fed twice a day. Each experimental group was divided into control group (group 1) and experimental groups 2-10. Among them, the control group was only given the basal diet, and the experimental groups 2 to 10 were respectively given the diets supplemented with 100 ppm of different 2-cyclic amino aliphatic diacid derivatives on the basis of the basal diet, as shown in Table 1.

[0153] During the whole feeding pro...

Embodiment 2

[0164] Example 2 The effect of 2-cyclic amino fatty acid derivatives on the performance of broilers

[0165]The experiment adopted a single-factor randomization design. 960 1-day-old broiler chickens with an average body weight of 50 g were selected and randomly divided into 10 treatment groups, with 6 replicates in each group, half male and female, and 16 replicates per replicate. Three yellow feather broilers. The chicken house and utensils were disinfected before the test. During the experimental period, cages were raised under the same feeding and management conditions in the same chicken house. The basal diet is mainly based on corn-soybean meal, and other antioxidants and growth promoters are not added during the whole feeding process. Each experimental group was divided into control group (group 1) and experimental groups 2-10. The control group was only given the basal diet, and 50ppm of different 2-cyclic amino aliphatic diacid derivatives were added to the basal d...

Embodiment 3

[0173] Example 3 Application of 2-Cyclic Amino Fatty Acid Derivatives in Fish Feed

[0174] The experimental fish used were grass carp, which was carried out by the aquatic farm of Guangzhou Inset Test Field. Healthy, lively and consistent size grass carp fingerlings were raised in large cages for 4 weeks before being used for formal breeding experiments. The experimental system was small floating cages. Small cages and temporary cages are placed in a 3500m test site 2 In the pond, the depth of the pond is about 1.5m, and the pond water is fully aerated bottom water. During the experiment, 420 grass carp that had been starved for 1 day were randomly divided into 7 groups, each group was set up with 4 replicates, and 15 fish were placed in each replicate. . Each experimental group was divided into control group (group 1) and experimental groups 2-7. The experimental feed was prepared by itself, in which the control group was only given the basal diet, and the experimental g...

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Abstract

The invention discloses 2-cycloamino fatty diacid derivatives as shown in formula (I), or their racemates, stereoisomers, geometric isomers, tautomers, solvates, or Application of feed acceptable salt in preparation of animal feed additive, wherein B is C 0 -C 9 Alkylene; R 1 and R 2 for C 1 -C 20 Alkyl or H; A is CH 2 , N, S or O; Z is C 0 -C 3 Alkylene, Y is C 2 -C 4 Alkylene; R 3 is ‑OH, ‑NH 2 ,-NO 2 , ‑CN, ‑SH, ‑X, ‑C 1 -C 5 Alkoxy, ‑C 1 -C 5 Alkyl or ‑C substituted by X 1 -C 5 Alkyl, wherein X is selected from F, Cl, Br or I; n is selected from 0-5 natural numbers. Animal breeding test results show that the 2-cyclic amino fatty diacid derivatives provided by the invention can be used as animal feed additives, and have a good effect of improving animal growth and production performance such as feed remuneration.

Description

technical field [0001] The invention relates to the field of animal feed additives, in particular to the application of a 2-cyclic amino aliphatic diacid derivative in the preparation of animal feed additives. Background technique [0002] Feed additives refer to small or trace substances added in the process of feed processing, production and use, including nutritional feed additives and general feed additives. Among them, general feed additives refer to a small amount or a trace amount of substances incorporated into the feed to ensure or improve the quality of the feed and improve the utilization rate of the feed. At present, the commonly used general feed additives that can efficiently and stably improve feed utilization rate and animal production performance mainly include: high-dose copper agent, high-dose zinc agent, feed antibiotics, chemically synthesized antibacterial agents, etc. However, the long-term use of these substances in the breeding industry will produce...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K20/132A23K20/137A23K50/30A23K50/60A23K50/75A23K50/80
Inventor 彭险峰
Owner GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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