The application discloses a
lactobacillus salivarius ZY-01 with anti-
salmonella and anti-inflammatory repair functions, the strain has been preserved in the China General
Microbiological Culture Collection Center on March 9, 2026, and the preservation number is CGMCC No. 37873. The strain can inhibit
salmonella,
escherichia coli and
staphylococcus aureus, can reduce the expression of IL-6, IFN-gamma and TNF-alpha pro-
inflammatory factors by inhibiting the JAK-STAT
signal pathway, and can promote the expression of IL-10 anti-
inflammatory factors and EGF, EGFR and TGF-beta1 mucosal repair factors, so that intestinal anti-
inflammation and mucosal repair are realized. The
lactobacillus salivarius ZY-01, bacterial liquid, bacterial
powder and
fermentation product thereof can be used as core raw materials of
animal feed additives, micro-ecological preparations and
veterinary drugs, are used for preventing and controlling
salmonella infection and improving intestinal health of animals in
animal breeding, and have a wide application prospect.