High-sensitivity online device for detecting HCN in expiratory air, and application thereof

A sensitive detection and exhaled breath technology, applied in measuring devices, evaluating respiratory organs, material analysis through electromagnetic means, etc., can solve the problems of limiting the detection sensitivity of HCN and limiting the yield of H

Inactive Publication Date: 2019-06-18
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
View PDF8 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the proton affinity of HCN is the same as that of H 2 O is very close (3 o + The proton transfer reaction between is reversible, limiting the H 2 CN + Yield of
In addition, due to the long reaction

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • High-sensitivity online device for detecting HCN in expiratory air, and application thereof
  • High-sensitivity online device for detecting HCN in expiratory air, and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] For the investigation of the device and application performance of a kind of highly sensitive on-line detection of HCN in exhaled air according to the present invention, the experiment is based on exhaled air matrix (4% CO 2 + relative humidity of 100% air) HCN is the analysis object, utilize this highly sensitive online analysis device to analyze the above-mentioned HCN gas of a series of concentrations on-line, to investigate the detection sensitivity and quantitative performance of the device and method for HCN. The exhaled gas flow rate entering the ionization zone was set at 100ml / min. The ionization mode of the ionization source in the experiment was ionized by a vacuum ultraviolet lamp assisted by 115ppmv acetone. The pressure in the ionization zone was maintained at atmospheric pressure, and the backflush flow rate was 1.0L / min. The above-mentioned HCN mixture was sampled and analyzed from low to high concentrations, and the sampling time was 0.5 min. figure 2 ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a high-sensitivity online device for detecting HCN in expiratory air, and an application thereof. The high-sensitivity online analysis system comprises an expiratory air sampling device, an expiratory air dehumidifying device, an air supply device and an HCN high-sensitivity detecting device. The application of the high-sensitivity online analysis system is to use the abovehigh-sensitivity online analysis system to directly convey human body expiratory air with a certain flow rate into the HCN high-sensitivity detecting device for analysis after the dehumidifying treatment of the dehumidifying device. HCN gases with different concentrations can be obtained by changing the flow rate of the human body expiratory air and the pumping speed of a pump, so as to obtain HCNfeature ion signal responses of different intensities. The human body expiratory air directly enters the HCN high-sensitivity detecting device without offline pre-enrichment, chemical derivation or other pretreatment steps, so that the operation is simple, the analysis is fast and accurate, the detection sensitivity is high, and the HCN of the sub-ppbv order can be detected.

Description

technical field [0001] The present invention relates to a high-sensitivity online detection device and application of HCN in exhaled air. Specifically, the high-sensitivity online analysis device is used to directly sample and analyze human exhaled air at a specific flow rate after dehumidification, so as to achieve high-sensitivity online analysis. Purpose of HCN in exhaled breath. Background technique [0002] As a genetic disease, cystic fibrosis is a chronic inflammatory lung infection that recurs periodically, causing progressive respiratory failure and, in severe cases, death. Currently, in the UK alone, more than 9,000 people suffer from the disease each year, with a particularly high incidence among children. Therefore, finding biomarkers of cystic fibrosis is crucial for the early diagnosis and treatment of the disease. The researchers found that one of the most common and important pathogens causing cystic fibrosis is called Pseudomonas aeruginosa, and the Pseudo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G01N27/64A61B5/08
Inventor 谢园园李海洋李庆运花磊
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap