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Optimal decumbent corydalis tuber stir-frying with vinegar process based on Critic-G1 method in combination with response surface method

A response surface method, response surface technology, applied in the direction of plant raw materials, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problem of no uniform standards for processing

Inactive Publication Date: 2020-01-21
龚千锋 +4
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There is no uniform standard for the processing of rice vinegar dosage A, soaking time B, frying temperature C, and frying time D of the above-mentioned vinegar-burning treatment process. In order to provide a reference for standardizing the processing technology that is not available in summer, the summer is determined by different conditions. The content of 4 kinds of alkaloids can be used to improve the quality control of summer non-medicinal materials

Method used

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  • Optimal decumbent corydalis tuber stir-frying with vinegar process based on Critic-G1 method in combination with response surface method
  • Optimal decumbent corydalis tuber stir-frying with vinegar process based on Critic-G1 method in combination with response surface method
  • Optimal decumbent corydalis tuber stir-frying with vinegar process based on Critic-G1 method in combination with response surface method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Based on the Critic-G1 method combined with the response surface method to optimize the preparation method of the non-vinegar broiling process in summer, the specific steps are as follows:

[0032] Use the CRITIC method to assign weights to the ingredients of vinegar-cured summer tea, and use it as an evaluation index for vinegar-cured summer tea. First, standardize the data, because summer tea contains toxic components of bicumulaline, and the lower the content The better, the table 2 in the

[0033]

[0034] Table 2

[0035] The content data of extract, proopine, palmatine hydrochloride, and tetrahydropalmatine were standardized [indicator components = (measured value-minimum value) / (maximum value-minimum value], moisture, ash, and piculidine content The data is standardized [index component = (maximum value - measured value) / (maximum value - minimum value) (1), and then according to

[0036]

[0037]

[0038] Among them, σi is the standard deviation of e...

Embodiment 2

[0041] Based on the Critic-G1 method combined with the response surface method to optimize the preparation method of the non-vinegar broiling process in summer, the specific steps are as follows:

[0042] G1 [13-15]The AHP method is an improved version of the Analytic Hierarchy Process. It is an evaluation method with a simple calculation method and no need for consistency testing. Level, according to the strength of pharmacological effects of summer ingredients and the factors affecting its main medicinal components, the first step is to determine the order of importance of each index as proto-opiate>palmatine hydrochloride=tetrahydropalmatine>bicumulin> Extract>Ash>Moisture, the second step is based on the formula (2) and the importance of index assignment table 3

[0043]

[0044] table 3

[0045]

[0046] Table 4

[0047] Determine the weight evaluation scale of each index, where r2=1.2r3=1, r4=1.1, r5=1.3, r6=1.1r7=1.1, and obtain the weight coefficient (wg ), a...

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Abstract

The invention discloses an optimal decumbent corydalis tuber stir-frying with vinegar process based on a Critic-G1 method in combination with a response surface method. The decumbent corydalis tuber vinegar-moxibustion process comprises the following components in parts by weight: 5 parts of decumbent corydalis tubers and A20% of rice vinegar. The optimal processing technology of decumbent corydalis tuber stir-frying with vinegar comprises: 30% of vinegar is used, the infiltration time is 1h, the stir-frying temperature is 170-190 DEG C, and the stir-frying time is 5 min. According to the method, key influence factors and ranges in the processing process are determined through a single-factor test; in combination with test and design of the response surface method, four factors of rice vinegar dosage A, the infiltration time B, the stir-frying temperature C and the stir-frying time D are investigated; the content of four alkaloids including moisture, ash, extract, protopine, palmatinehydrochloride, tetrahydropalmatine and bicuculline is taken as a measurement index, a weight coefficient is calculated by combining a CRITIC method with a G1 method, an OD value is calculated, and theoptimal decumbent corydalis tuber stir-frying with vinegar process in combination with the response surface method can be used for quality control of a decumbent corydalis tuber medicinal material.

Description

technical field [0001] The present invention relates to summer vinegar-free roasting process, in particular to optimizing summer vinegar-free roasting process based on Critic-G1 method combined with response surface method. Background technique [0002] Vinegar-burning is the method of adding a certain amount of vinegar to stir-fry the net-selected or cut medicine, which is called vinegar-burning method. Vinegar is sour, bitter and warm in nature, and it mainly enters the liver meridian blood. Therefore, the method of vinegar broiling is mostly used for soothing the liver and relieving stagnation, dispelling blood stasis and relieving pain, and conquering water-dispelling medicines. The operation method of vinegar broiling includes: 1. Stir-fry the medicine after mixing vinegar to clean or cut the medicine , add a certain amount of rice vinegar, mix well, and moisten it slightly. After the vinegar is exhausted, put it in a frying container, fry it with a slow fire to a certa...

Claims

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Application Information

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IPC IPC(8): G16C20/70G16C20/50A61K36/66
CPCA61K36/66G16C20/50G16C20/70
Inventor 龚千锋严丽萍于欢温柔李潮
Owner 龚千锋
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