142 results about "Corydalis yanhusuo" patented technology

The invention belongs to the technical field of traditional Chinese medicines, and provides an external traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment. The traditional Chinese medicine composition comprises the following components: prepared kusnezoff monkshood root, lycopodium clavatum, garden burnet, rheum officinale, radix clematidis, ligusticum wallichii, rhizoma zingiberis, angelica sinensis, Sinkiang lithospermum, peach kernel, fried gardenia, turmeric, radix angelicae pubescentis, asarum, notopterygium root, sappan wood, red paeony root, garden balsam stem, vinegar frankincense, vinegar corydalis tuber, vinegar myrrh, vinegar rhizoma cyperi, bran-fried fructus aurantii and golden cypress. The invention further discloses a preparation method and application of the traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment. The traditional Chinese medicines perform respective functions in monarch, minister, assistant and guide, the whole formula has the effects of promoting blood circulation to remove blood stasis, activating meridians to stop pain, dispelling wind and eliminating dampness, and reducing swelling and removing stasis, a synergistic treatment effect on tendon injury, blood stasis, swelling and pain and bone impediment is formed through a multi-target-point synergistic effect, the limitation that a traditional Chinese medicine with a single effect is difficult to comprehensively deal with is solved, and the effect of treating both symptoms and root causes is achieved; the traditional Chinese medicine composition has remarkable social benefits and clinical application value.

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine composition for wound healing and a preparation method thereof.The traditional Chinese medicine composition used in the early stage comprises 10-12 parts of rheum officinale, 5-6 parts of coptis chinensis, 10-12 parts of scutellaria baicalensis, 10-12 parts of golden cypress, 10-12 parts of corydalis tuber, 6-7 parts of pseudo-ginseng, 5-6 parts of pollen typhae, 4-5 parts of dragon's blood, 10-12 parts of sanguisorba officinalis, 10-13 parts of ramulus mori and 10-12 parts of gallnut; the traditional Chinese medicine composition used in the middle stage is prepared from 10-12 parts of radix astragali, 10-12 parts of radix angelicae sinensis, 10-12 parts of radix salviae miltiorrhizae, 10-12 parts of talc, 10-12 parts of ramulus mori, 10-12 parts of gallnut, 10-12 parts of rhizoma chuanxiong, 4-5 parts of resina draconis, 10-12 parts of frankincense and 10-12 parts of myrrh; the traditional Chinese medicine composition used in the later period comprises 10-12 parts of radix astragali, 10-12 parts of radix dipsaci, 10-12 parts of radix angelicae sinensis, 10-12 parts of rhizoma chuanxiong, 10-12 parts of gallnut, 10-12 parts of ramulus mori, 10-12 parts of radix codonopsis, 10-12 parts of radix salviae miltiorrhizae, 10-12 parts of radix morindae officinalis and 10-12 parts of talc. Wound treatment is divided into three stages, the cure rate of chronic refractory wounds (CRW) can be remarkably increased, inflammatory factors are inhibited, and tissue regeneration is promoted.

The invention discloses a traditional Chinese medicine composition for treating acute gout, an external gel and a preparation method thereof, and the traditional Chinese medicine composition comprises the following raw material components in parts by mass: 5-20 parts of radix clematidis, 5-20 parts of polygonum cuspidatum, 5-20 parts of honeysuckle stem, 5-15 parts of radix aconiti preparata, 5-15 parts of pine nodular branch, 1-5 parts of corydalis tuber and 1-3 parts of asarum. The gel disclosed by the invention is an external gel prepared by researching through a traditional Chinese medicine composition intermediate extraction process and a preparation forming process, has the effective effects of directly reaching an affected part, taking effect quickly, being good in patient compliance and the like, and can realize industrial production through pilot scale-up experiment verification. Animal experiment research results show that the radix clematidis pain-relieving gel has remarkable anti-inflammatory and pain-relieving effects.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to an external traditional Chinese medicine ointment for treating acute gouty arthritis and a preparation method thereof. Comprising the following components in parts by mass: 18-22 parts of rheum officinale, 20-26 parts of turmeric, 15-19 parts of cortex phellodendri, 15-19 parts of indigo naturalis, 15-19 parts of rhizoma smilacis glabrae, 14-18 parts of radix clematidis, 14-18 parts of moutan bark, 14-18 parts of herba lycopi, 10-14 parts of semen plantaginis, 8-12 parts of radix stephaniae tetrandrae, 8-12 parts of rhizoma corydalis and 5-9 parts of liquorice. The ointment not only aims at inflammation and pain in the acute stage of gout, but also promotes uric acid excretion through medicines such as rhizoma smilacis glabrae and semen plantaginis, and has a certain auxiliary uric acid reduction effect. The compound design of the traditional Chinese medicine composition integrates the functions of clearing heat and promoting diuresis and promoting blood circulation to remove blood stasis, body metabolism is regulated from multiple targets, symptoms are relieved, pathogenesis conditioning is also considered, and a more comprehensive solution is provided for treatment of gouty arthritis.

The application belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating abdominal distension and diarrhea of cold-heat complex type and a preparation method thereof. The technical scheme points of the traditional Chinese medicine composition are as follows: the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 3-6 parts of perilla, 3-10 parts of dried ginger, 3-12 parts of eucommia, 3-10 parts of scrophularia, 2-6 parts of coptis, 10-20 parts of fried coix seed, 6-10 parts of clear pinellia, 3-10 parts of dried tangerine or orange peel, 10-15 parts of poria, 6-10 parts of wheat-cooked atractylodes, 6-10 parts of vinegar-cured corydalis, 6-10 parts of vinegar-cured bupleurum, 6-10 parts of pericarpium zephyritae, 6-10 parts of chuanxiong, 6-10 parts of magnolia officinalis, 6-10 parts of fried hawthorn fruit, 3-6 parts of platycodon, and 3-10 parts of fried licorice. The traditional Chinese medicine composition and the traditional Chinese medicine water pill prepared from the traditional Chinese medicine composition have the effect of treating abdominal distension and diarrhea of cold-heat complex type.

The invention relates to the field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 5-15 parts of pericarpium citri reticulatae viride; 5-15 parts of szechwan chinaberry fruit; 5-15 parts of the root of three-nerved spicebush; 5-15 parts of radix angelicae dahuricae; 10-20 parts of herba lycopi; 10 to 20 parts of herba patriniae; 4 to 8 parts of frankincense; 4 to 8 parts of myrrh; 5 to 15 parts of rhizoma corydalis; 10 to 20 parts of caulis spatholobi; 5 to 15 parts of diverse wormwood herb; 10 to 20 parts of cowherb seed; 5-15 parts of radix curcumae; and 4-8 parts of fennel. The traditional Chinese medicine composition can significantly improve the symptoms of chronic prostatitis, regulate the syndromes of traditional Chinese medicine and improve the life quality of patients, and has good safety and patient compliance.

This invention provides SSR molecular markers associated with the yield trait of Corydalis yanhusuo, belonging to the field of molecular genetics. This invention utilizes 24 pairs of SSR markers to perform regression analysis on the genotype and yield trait of individual Corydalis yanhusuo individuals. Using the GLM program, association loci for the yield trait of Corydalis yanhusuo were detected. The SSR molecular markers CYC2-4 and CYC8-10 were found to be highly significantly associated, explaining 16.72% and 14.06% of the phenotypic variation, respectively. The primers provided by this invention for amplifying the aforementioned SSR molecular markers can be used to screen for high-yielding Corydalis yanhusuo germplasm, locate key genes controlling yield traits, and for marker-assisted breeding, which is of great significance for cultivating high-yielding Corydalis yanhusuo varieties.

This invention discloses a pharmaceutical composition and its preparation method for treating atrophic gastritis, precancerous lesions of the stomach, and stomach cancer, belonging to the field of traditional Chinese medicine preparation technology. The pharmaceutical composition is prepared by a specific two-step microbial fermentation process using Astragalus membranaceus, Hericium erinaceus, Curcuma zedoaria, Actinidia chinensis root, Camptotheca acuminata fruit, Hedyotis diffusa, Coptis chinensis, Taraxacum mongolicum, Viola yedoensis, Corydalis yanhusuo (processed with vinegar), Phellodendron chinense, Solanum nigrum, Scutellaria baicalensis, Panax notoginseng, Zingiber officinale, Piper cubeba, Cuttlebone, Fritillaria thunbergii, roasted soybean, and red yeast rice. This invention significantly improves the bioavailability of the active pharmaceutical ingredients through the synergistic effect of the multifunctional groups of traditional Chinese medicine and the enhanced effect of microbial fermentation. It can systematically reverse gastric mucosal atrophy and intestinal metaplasia, effectively improve microcirculation, and inhibit Helicobacter pylori, while also exhibiting good safety. This provides a novel and effective treatment for the aforementioned gastric diseases.

This invention relates to the field of traditional Chinese medicine composition technology, and particularly to a method of using, preparing, and applying a traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from raw materials comprising a first component, a second component, a third component, and a fourth component: the first component comprises a mixture of raw oyster shell, prunella vulgaris, and fritillaria thunbergii; the second component comprises a mixture of angelica sinensis, scorpion, notoginseng, and cattail pollen; the third component comprises one or more of lindera strychnifolia, chuanxiong rhizome, cyperus rotundus, and corydalis yanhusuo; the fourth component comprises one or more of fenugreek, angelica dahurica, and fennel; the mass ratio of the first component to the second component is 1.3–2:1. This traditional Chinese medicine composition can not only significantly prevent and alleviate dysmenorrhea symptoms in patients with acute menstrual cramps (AM), but also improve other accompanying symptoms during menstruation in AM patients, such as heavy menstrual bleeding.

This invention belongs to the field of traditional Chinese medicine technology and discloses a traditional Chinese medicine composition for treating dysmenorrhea and its preparation method as a patch. Specifically, it relates to a traditional Chinese medicine composition for treating dysmenorrhea, comprising the following components in parts by weight: 10-14 parts of Ligusticum chuanxiong, 10-14 parts of Notopterygium incisum, 8-12 parts of processed myrrh, 2-6 parts of leech, 13-17 parts of processed Cyperus rotundus, 13-17 parts of Corydalis yanhusuo, 10-14 parts of earthworm, and 1-5 parts of dragon's blood. The traditional Chinese medicine composition for treating dysmenorrhea provided by this invention is based on the essence of the traditional Chinese medicine theory of "free flow prevents pain," with a rigorous combination of principal, assistant, and adjuvant herbs. The entire formula works synergistically to dispel wind and cold, invigorate blood circulation, remove blood stasis, regulate qi, and relieve pain, addressing both the symptoms and the root cause. After preparation as a patch, the medicine penetrates the skin and is absorbed through acupoints, resulting in rapid onset of action, convenient use, high safety, and good patient compliance. Clinical trials have shown that this invention has a good relieving effect on dysmenorrhea, with rapid onset and stable efficacy, overcoming many shortcomings of existing methods.

The invention relates to the technical field of physical therapy products, in particular to a traditional Chinese medicine composition for treating muscle fascia injury and a special muscle effect patch structure. The traditional Chinese medicine composition comprises the following raw materials: premna fulva, safflower, corydalis tuber, garden balsam stem, corydalis amabilis, lycopodium clavatum, ground beetle, cassia twig, borneol and white spirit. The special muscle effect patch structure comprises a fixing area and a cross-shaped structure formed by connecting four anchoring parts, the anchoring parts are connected with the fixing area, a medicine ball is connected to the center of the fixing area, and a plurality of medicine outlet holes are formed in the wall face of the medicine ball with liquid absorption filler inside. The surface of the targeting part is provided with a bonding layer used for being adhered to the skin, the bonding layer is connected with release paper, and the release paper is provided with a protruding film matched with the medicine balls. Through the unique structural design and cooperation of the fixing area, the anchoring part, the targeting part, the medicine ball and the like, muscles are relaxed in a physical mode, dynamic and active medicine permeation and physical pressing are achieved, and the pressing and rebounding effects of manual massage are simulated, so that transdermal delivery of medicine components is better achieved.

The invention discloses an anti-hepatic fibrosis traditional Chinese medicine compound preparation and application thereof.The anti-hepatic fibrosis traditional Chinese medicine compound preparation is prepared from herba artemisiae scopariae, parched fructus gardeniae, roasted rhizoma atractylodis macrocephalae, turtle shells, radix bupleuri, rhizoma corydalis, herba desmodii styracifolii and herba scutellariae barbatae, all the medicines are compatible and have a synergistic effect, and the effects of clearing heat and promoting diuresis, promoting blood circulation to remove blood stasis, softening hardness to dissipate stagnation and tonifying spleen and qi are achieved together; the liver fibrosis is intervened from a plurality of target spots. Heat clearing and diuresis promoting can eliminate damp-heat evil damaging the liver; blood circulation of the liver can be improved by promoting blood circulation to remove blood stasis, and blood stasis is eliminated; the liver fibrosis hyperplasia can be resisted by softening hardness to dissipate stagnation, and the liver tissue hardening trend can be reversed; spleen invigorating and qi replenishing can enhance healthy qi of the body and improve the self-repairing ability of the liver. The multi-target and all-around treatment mode not only conforms to the holism concept of traditional Chinese medicine, but also conforms to the understanding of modern medicine on multi-factor and multi-link pathogenesis of hepatic fibrosis.

The present application belongs to the technical field of traditional Chinese medicine, and particularly relates to a medicinal composition for treating respiratory diseases and a preparation method and use thereof. The medicinal composition is prepared from raw medicinal materials of white mustard seed, asarum, cassia bark, corydalis, dried tangerine or orange peel, Szechuan lovage root, ginger and green onion white, and the components are combined to have a remarkable effect on treating respiratory diseases, and the incidence of skin discomfort or adverse reactions is significantly reduced after use. The traditional Chinese medicinal composition has a remarkable effect on treating respiratory diseases, and the incidence of skin discomfort or adverse reactions is significantly reduced after use, which is specifically manifested in that most cases do not foam after use, and only a few cases will have slight foaming, thereby reducing the risk of scarring. In particular, the safety of the medicinal composition for children is unanimously affirmed by the families of patients. In addition, the ginger and green onion white in the traditional Chinese medicinal composition can improve the absorption capacity of the medicinal composition through acupoints, and the moxibustion feeling is better, and the qi is easier to obtain and the feeling of obtaining qi is better.

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating diarrhea-type irritable bowel syndrome. The traditional Chinese medicine composition comprises 4-16 g of codonopsis pilosula, 4-16 g of roasted rhizoma atractylodis macrocephalae, 3-12 g of fructus psoraleae, 2-8 g of galangal, 3-12 g of poria cocos, 4-16 g of white hyacinth bean, 2-8 g of elecampane, 3-12 g of corydalis tuber and 2-8 g of honey-fried licorice root. The traditional Chinese medicine composition provided by the invention has the effects of tonifying spleen, clearing damp, warming middle-jiao, stopping diarrhea and the like, and can obviously improve clinical symptoms of IBS-D patients and model animals, specifically, the clinical symptoms are improved, the water content of excrement is reduced, and visceral hypersensitivity is relieved.

The application relates to the medical technology field and discloses an oral liquid capable of easily expelling stones and clearing toxins and a preparation process thereof. The raw materials of the oral liquid include chicken gizzard suet, dandelion, houttuynia cordata, sea golden sand, plantain, corn silk, money grass, corydalis, licorice and oligofructose with a specific polymerization degree. The preparation process comprises grouping extraction of the raw materials, purification of the chicken gizzard suet by using concentration with forced circulation and bottom feeding type jet flow, pressure filtration of the sea golden sand by using the endogenous fiber of the houttuynia cordata to construct a filter aid skeleton, and finally constant-temperature liquid preparation and sterilization by using a micropore filter membrane to obtain the finished product. Oligofructose is introduced into traditional Chinese medicine to promote proliferation of intestinal oxalic acid degrading bacteria, and plant components are used to block stone generation from a metabolic source; specific fluid mechanics separation and non-thermal sterilization processes solve the problems of protein aggregation and micropore blockage of microspores, and the configuration stability of heat-sensitive medicinal components and prebiotic molecules is maintained.

The present application relates to the technical field of Qizixuexu agent sticking, especially to a Qizixuexu acupoint sticking and a preparation method thereof, the Qizixuexu acupoint sticking comprises the following raw materials and weight parts, Anarhichas lupus, 3-7 parts; red peony root, 8-12 parts; peach kernel, 8-12 parts; gardenia, 8-12 parts; myrrh in vinegar, 8-12 parts; olibanum in vinegar, 8-12 parts; baizhi, 8-12 parts; sanqi, 8-12 parts; rhubarb, 8-12 parts; xiangfu, 8-12 parts; corydalis, 8-12 parts; safflower, 8-12 parts. The present application improves the Qizixuexu related symptoms of the elderly patients by preparing a specific Qizixuexu acupoint sticking, plays a role in multiple targets and multiple directions, and improves the treatment effect of the patients.

The present application relates to the field of traditional Chinese medicine, and specifically relates to a kind of external use traditional Chinese medicine composition for treating thin endometrium, which is composed of the following raw medicinal materials: cinnamon 250-300g, fennel 250-300g, Corydalis 250-480g, Cnidium 250-400g, safflower 250-300g, Evodia 150-200g, mugwort leaf 250-300g, and ginger juice 500-600ml.The external use combined medicine of the present application can obviously improve the symptoms of dysmenorrhea, little menstrual flow, dark red menstrual color, and more menstrual blood clots, thicken the endometrial thickness during ovulation, and improve the clinical pregnancy rate of patients with thin endometrium.The external use traditional Chinese medicine is absorbed through skin, does not burden liver and kidney functions, achieves the purposes of warming meridians, activating blood and resolving stasis through the action of acupoint meridian, has little side effects, and is convenient for promotion.

The invention discloses a compound preparation for treating osteoarthritis and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations. Comprising the following raw materials in parts by weight: 15-19 parts of wine-processed radix achyranthis bidentatae, 13-15 parts of salted eucommia ulmoides, 11-13 parts of angelica sinensis, 9-11 parts of bran-fried rhizoma atractylodis, 11-13 parts of semen coicis, 5-7 parts of poria cocos, 4-6 parts of wine-processed flos carthami, 4-6 parts of vinegar-processed rhizoma corydalis, 4-6 parts of radix paeoniae alba, 8-10 parts of sand-scalded rhizoma drynariae and 4-6 parts of honey-fried liquorice. According to the compound preparation for treating osteoarthritis and the preparation method, arthralgia and stiffness can be rapidly relieved, long-acting repair and adjustment can be achieved, intestinal flora and systemic immunity are synergistically adjusted through targeted colon, and the pathological process of osteoarthritis is blocked from multiple ways. Clinical verifications show that the curative effect of the traditional Chinese medicine composition is obviously superior to that of conventional preparations and first-line western medicines, the safety is better, and an innovative treatment choice which takes effect quickly, takes effect for a long time and treats both symptoms and root causes is provided for patients.

The present application relates to the field of medical or cosmetic formulations, the field of biopharmaceutical manufacturing technology and the field of preparation manufacturing technology, and in particular to a cosmetic composition, a preparation method and application thereof.The cosmetic composition comprises an active ingredient; the active ingredient comprises a chloranthus specious extract and a rhizoma corydalis extract; and the weight ratio of the chloranthus specious extract and the rhizoma corydalis extract is 0.6:1-1:1.The chloranthus specious extract and the rhizoma corydalis extract in the cosmetic composition provided by the present application are synergistic with each other, and have excellent soothing and repairing effects.

This invention provides SSR molecular markers associated with the proliferation trait of Corydalis rhizomes, belonging to the field of molecular genetics. Trait correlation analysis shows that Corydalis rhizomes proliferation is a key factor affecting its yield. This invention utilizes 24 pairs of SSR markers to perform regression analysis on the individual genotype and rhizome proliferation trait of Corydalis rhizomes. The association loci for Corydalis rhizomes proliferation were detected using the GLM program, explaining 18.73% of phenotypic variation, with the SSR molecular marker CYC2-8 showing a highly significant correlation. The primers provided by this invention for amplifying the aforementioned SSR molecular markers can be used to screen for superior Corydalis rhizomes with high rhizome proliferation, locate key genes controlling the rhizome proliferation trait, and for marker-assisted breeding, which is of great significance for cultivating high-yielding Corydalis rhizomes varieties.

This invention relates to the technical field of food processing, specifically to a method for preparing and applying probiotics that can improve intestinal colonization efficiency. The method uses corydalis yanhusuo protein as one of the reaction substrates and employs a two-stage fermentation process to cultivate probiotics. In the first stage of fermentation, the probiotics rapidly proliferate and produce spores. In the second stage of fermentation, they form a biofilm. The resulting probiotic fermentation broth is then dried and pulverized to produce the probiotic powder that improves intestinal colonization efficiency. This invention's preparation method is the first to employ a high-density fermentation mode that enhances the formation of a probiotic biofilm. By adjusting the initial fermentation medium ratio and fermentation parameters, the probiotics rapidly proliferate and produce spores. In the second stage of fermentation, the medium is supplemented and parameters are changed to achieve biofilm formation. This method solves the technical difficulties of slow proliferation and low biomass in single-stage biofilm static culture of probiotics, as well as the problems of poor processing tolerance and intestinal membrane adhesion of planktonic probiotics.

The invention provides a stomach medicine capsule and a preparation method thereof, and belongs to the field of traditional Chinese medicine preparations, the preparation method comprises the following steps: extracting medicinal materials, crushing, drying, granulating, filling and packaging, extracting elecampane, egg shell, dried alum, calcined nacre mother of pearl and cuttlebone by using drinking water, concentrating decoction into clear paste, spray-drying into fine powder, extracting vinegar-processed corydalis tuber by using an aqueous solution of 1% glacial acetic acid, and packaging. Concentrating the decoction into clear paste, performing one-step granulation on the fine powder and the clear paste, filling capsules, and packaging. According to the stomach medicine capsule prepared by the invention, the production efficiency of granulation and the stability of the main component tetrahydropalmatine are improved.

The invention provides a traditional Chinese medicine compound which is prepared from the following raw material medicines: rhizoma smilacis glabrae, rhizoma dioscoreae septemlobae, semen coicis, rhizoma curcumae longae, herba taxilli, radix salviae miltiorrhizae, cortex phellodendri, rhizoma acori graminei, plantain herb, rhizoma atractylodis macrocephalae, wine-treated rhubarb, radix angelicae pubescentis, bran-fried rhizoma atractylodis and vinegar-treated rhizoma corydalis, and also provides application of the traditional Chinese medicine compound composition in medicines for treating gout and gouty nephropathy. In addition, the invention also provides a preparation method of the sustained-release granule of the compound composition, which comprises the following steps: firstly, preparing the raw medicinal materials into a traditional Chinese medicine fluid extract, then adding the filler into the traditional Chinese medicine fluid extract, stirring to form a soft material, passing the soft material through a swinging granulator, and drying to obtain a medicine-containing pill core; and putting the pill cores into a fluidized bed, laterally spraying the slow-release coating solution, drying, and sieving to prepare the slow-release granules. The prepared traditional Chinese medicine formula sustained-release granules can release 90% or above within 8-10 hours, have a good constant-speed sustained-release characteristic, can meet the clinical requirement of 1-2 times of administration every day, and have good clinical application prospects and market value.

The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating gouty arthritis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following components: 5g to 15g of pseudobulbus cremastrae seu pleiones, 10g to 20g of rhizoma polygoni cuspidati, 15g to 30g of semen coicis, 15g to 30g of rhizoma smilacis glabrae, 15g to 30g of bulbus lilii, 10g to 20g of rhizoma dioscoreae septemlobae, 10g to 25g of rhizoma corydalis, 10g to 20g of radix paeoniae rubra, 15g to 30g of rhizoma dioscoreae, 10g to 20g of radix The preparation method of the traditional Chinese medicine composition comprises the following steps: mixing the components according to the formula ratio, decocting with water twice, combining filtrate, continuously decocting and concentrating to 400mL. The traditional Chinese medicine composition disclosed by the invention can relieve arthralgia caused by damp-heat toxin stasis in the acute attack period of gouty arthritis, effectively controls the acute attack of gout, reduces adverse reaction and is good in safety.

This invention provides a traditional Chinese medicine composition for treating osteoarthritis, prepared from the following raw materials in the indicated weight ratios: Corydalis Rhizome 8-12 parts, Red Peony Root 7.2-10.8 parts, Achyranthes Root 7.2-10.8 parts, Clematis Root 7.2-10.8 parts, White Peony Root 7.2-10.8 parts, Chaenomeles Root 7.2-10.8 parts, and Liquidambar Root 7.2-10.8 parts. This invention also provides a method for preparing this traditional Chinese medicine composition and its uses. This traditional Chinese medicine composition prioritizes promoting blood circulation and removing blood stasis, while also relaxing muscles and tendons, and nourishing blood and soothing the liver, thus achieving the combined effects of "promoting blood circulation and removing blood stasis, relaxing muscles and tendons." The combination of warming and cooling properties, along with a combination of tonifying and purging effects, removes blood stasis, clears the meridians, and improves joint mobility, thereby relieving knee pain, swelling, and limited mobility. Modern pharmacological studies have shown that the drug of this invention has anti-inflammatory, analgesic, microcirculation-improving, and cartilage-repair-promoting effects, which are highly compatible with the treatment needs of knee osteoarthritis.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for promoting growth and development of spleen-kidney deficiency type short children and application thereof.The traditional Chinese medicine composition is prepared from, by weight, 3 parts of pseudo-ginseng, 9 parts of cinnamon, 10 parts of raw hawthorn, 10 parts of ramulus mori, 10 parts of radix salviae miltiorrhizae, 10 parts of rhizoma corydalis, 9 parts of herba epimedii, 9 parts of rhizoma drynariae and 9 parts of radix dipsaci. The traditional Chinese medicine composition disclosed by the invention recovers the fundamental pathogenesis of spleen-kidney deficiency and promotes the growth and development of children through comprehensive conditioning of warming yang and tonifying kidney, tonifying qi and strengthening body and promoting blood circulation to remove blood stasis.

The application discloses a kind of drug composition for treating cervical spondylosis and its preparation and application, belong to traditional Chinese medicine composition technical field, the drug composition includes the following component by weight fraction: 6-28 parts of cornus officinalis, 6-28 parts of antler, 6-20 parts of cassia twig, 6-30 parts of kudzu root, 10-40 parts of astragalus, 6-16 parts of peach kernel, 6-16 parts of safflower, 6-20 parts of purple salvia miltiorrhiza, 6-20 parts of wine dengue, 6-20 parts of chuanxiong, 6-20 parts of red peony root, 6-20 parts of turmeric, 6-20 parts of frankincense, 6-20 parts of myrrh, 6-20 parts of notopterygium, 6-20 parts of rinkhals, 6-20 parts of sea wind, 6-20 parts of giant knotweed, 6-20 parts of corydalis, 6-15 parts of licorice.The drug composition can be added pharmaceutically acceptable adjuvant, and be made into preparation.The drug composition and preparation can be used for preparing the drug for treating cervical spondylosis mainly with wind, cold and damp.

The invention provides a preparation method of a traditional Chinese medicine dispersion liquid containing self-assembled nanoparticles, which comprises the following steps: mixing fructus piperis longi, rhizoma corydalis, radix angelicae, ligusticum wallichii, ligusticum and indigo naturalis, crushing, sieving to obtain a traditional Chinese medicine crushed material, adding purified water, carrying out ultrasonic extraction and suction filtration to obtain a traditional Chinese medicine extracting solution, centrifuging, removing precipitate, filtering supernate by a filter membrane, and drying to obtain the traditional Chinese medicine dispersion liquid containing the self-assembled nanoparticles. And carrying out ultrafiltration centrifugation, sucking liquid in the tube, and carrying out high-speed centrifugation to obtain the traditional Chinese medicine dispersion liquid containing the self-assembled nanoparticles. The invention also provides application of the traditional Chinese medicine dispersion liquid. The prepared traditional Chinese medicine dispersion liquid containing the self-assembled nanoparticles can relieve rat migraine caused by nitroglycerin, can remarkably improve the mechanical pain threshold and the heat pain threshold of model rats and remarkably promote callback of inflammatory factors and migraine markers in brain tissues of chronic migraine rats, and is used for preparing drugs for improving migraine through nasal administration.

This invention relates to the field of traditional Chinese medicine technology, specifically to a granule for promoting urination and eliminating stones, its preparation method, and its application. The granule comprises the following ingredients: *Lysimachia christinae*, *Pyrrosia lingua*, *Cynanchum paniculatum*, talc, stir-fried chicken gizzard lining, *Polygonum aviculare*, *Dianthus superbus*, *Plantago asiatica*, *Tetrapanax papyriferus*, *Poria cocos*, *Coix lacryma-jobi*, *Paeonia lactiflora*, vinegar-processed *Corydalis yanhusuo*, *Astragalus membranaceus*, and *Achyranthes bidentata*. The entire formula integrates clearing heat and promoting urination, dissolving stones, tonifying qi and relieving pain, and guiding the medicine downwards. It primarily focuses on purging while supplementing with tonifying, achieving the combined effects of clearing heat and promoting diuresis, and dissolving stones. It is used for damp-heat accumulation, stone accumulation, or combined with deficiency of vital energy leading to urinary tract infections, stones, or hematuria. Symptoms include frequent urination, burning and stinging pain, yellow or reddish urine, abdominal cramps, difficulty urinating or stones in the urine, red tongue with yellow or greasy coating, and a slippery and rapid pulse. This composition has the effects of clearing heat and promoting diuresis, relieving strangury and expelling stones. It is used for heat strangury, stone strangury and hematuria caused by damp-heat accumulation, with symptoms such as frequent urination, burning and stinging pain, yellow or reddish urine or blood in urine, lower back and abdominal colic, difficulty in urination or gravel in urine, red tongue with yellow or yellow and greasy coating, and slippery and rapid pulse.