Thixotropic bingham plastic fluid contraceptive method

A technology with thixotropy and fluid properties, applied in the direction of female contraceptives, rigid containers, pharmaceutical formulations, etc., can solve problems such as pain, pain, and contraceptive methods that are not ideal options

A technology with thixotropy and fluid properties, applied in the direction of female contraceptives, rigid containers, pharmaceutical formulations, etc., can solve problems such as pain, pain, and contraceptive methods that are not ideal options

CN110770138AInactive Publication Date: 2020-02-07乔舒亚・D・莱文 +1
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  • Thixotropic bingham plastic fluid contraceptive method
  • Thixotropic bingham plastic fluid contraceptive method
  • Thixotropic bingham plastic fluid contraceptive method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0048] The present disclosure relates to a method of contraceptive barrier utilizing a thixotropic composition referred to as a contraceptive product ("CP") as described below. Aspects of the disclosure include applicators that may be used with the methods.

[0049] The CPs used within the method possess unique and functionally important rheological and biological properties. CP can be defined as a composition that is a gel suspension that: a) remains in a semi-solid state when at rest (e.g., at room or body temperature); b) upon introduction of at least a sufficient amount of shear stress (i.e. "yielding shear stress amount"), can change from the aforementioned semi-solid state to the liquid state; and c) return to the above-mentioned state within a relatively short period of time (for example, less than 3 seconds) when the shear stress dissipates and returns to the quiescent state semi-solid. Because of these properties, CPs can be described as having properties similar to...

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Abstract

A method of contraception for a female subject is provided, as well as a contraceptive product and a contraceptive product system. The method includes spraying an amount of a thixotropic contraceptiveproduct that has Bingham fluid characteristics into a subject's vaginal vault, which contraceptive product comprises a viscosity increasing agent in the range of about 4-8% by weight and an aqueous carrier. The thixotropic contraceptive product is sprayed in a manner that forms a barrier configured to prevent spermatozoa from entering a cervix of the subject.

Description

[0001] This patent application claims the benefit of U.S. Provisional Application No. 62 / 488,911 filed April 24, 2017, which is hereby incorporated by reference in its entirety. technical field [0002] The present invention relates to materials and methods for contraceptive barriers, including applicators and methods of using the applicators. Background technique [0003] All currently available forms of barrier methods for women have significant disadvantages. Disadvantages of using a diaphragm or cervical cap include: 1) time, expense, and physical discomfort of fitting in with the device; 2) insertion and removal of the device at the right time involves necessary planning; 3) some women have difficulty inserting the device; 4) Some women experience pain and general discomfort when using the device; 5) The device requires a high degree of hygienic maintenance, which may be difficult in the absence of clean water; 6) The device needs to be used with spermicide, which Seme...

Claims

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Application Information

Patent Timeline
07 Feb 2020
Publication
CN110770138A
IPC
B65D35/00; A61F6/06
CPC
A61F6/06; A61K9/0034; A61K9/06; A61K47/38
Inventors
乔舒亚·D·莱文; 罗伯特·A·莱文