Nicotinic acid skin reaction image analysis method and equipment

Abstract

The invention relates to a nicotinic acid skin reaction image analysis method and equipment. The method comprises the following steps: pasting a nicotinic acid methyl ester patch on the skin of the forearm of a subject; acquiring a nicotinic acid reaction area image of the forearm skin of the subject and analyzing the nicotinic acid reaction area image to generate an identification mark graph of nicotinic acid skin reaction of the subject; obtaining an identification mark graph in the existing diagnosis data as an input to train a prediction model of nicotinic acid skin reaction; inputting anidentification mark graph of the nicotinic acid skin reaction of the subject into the prediction model, and obtaining the prediction result of the nicotinic acid skin reaction of the subject. According to the method, the problem that at present, a rapid and objective quantification tool is lacked for the nicotinic acid skin reaction degree is solved, an image processing and analysis method is introduced, schizophrenia and other severe psychosis serve as research and development service and application objects, and quantitative detection of the nicotinic acid skin reaction degree is achieved.

Description

technical field [0001] The invention relates to the technical field of psychiatric diagnosis, in particular to a niacin skin reaction image analysis method and equipment. Background technique [0002] Niacin is a water-soluble vitamin, which can cause skin flushing reaction through contact with human skin. A large number of experimental data have proved that abnormal nicotinic acid response is one of the endophenotype characteristics of schizophrenia. The detection method of abnormal nicotinic acid response in schizophrenia has been using the observation evaluation method in the past. This method is mainly based on artificially observing the degree of skin flushing and giving a score, which is highly subjective and the data is not quantitative. In recent years, the laser Doppler method has been proposed, that is, the laser Doppler instrument is used to quantify the degree of niacin response by detecting the blood flow velocity under the skin exposed to niacin, but this metho...

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Problems solved by technology

In recent years, the laser Doppler method has been proposed, that is, the laser Doppler instrument is used to quantify the degree of niacin response by detecting the blood flow velocity under the skin exposed to niacin, but this method is different from the data collected by the observation and evaluation method. , so the data collected by the observation evaluation method cannot be used as a reference for the previous data, and it cannot be used as a clinically available detection method

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