80 results about "Skin reaction" patented technology

Microprojection members (10) having a reservoir containing an antigenic agent and methods of using such members to vaccinate mammals (e.g., humans) are disclosed. The microprojection members are used to transdermally deliver an antigenic agent (e.g., a vaccine antigen) with substantially reduced skin reactions. This is achieved by delivering an induction amount and thereafter delivering one or more subsequent booster amounts. The induction amount is relatively larger than the booster amount. This technology has broad applicability for a wide variety of therapeutic vaccines to improve efficacy and convenience of use.

The present application is directed to various compositions to treat the itching and conditions that result from contracting poison ivy, poison oak, and poison sumac, as well as other plant and substances that contain substances that lead to a skin reaction but that upon removal alleviate the symptoms of the condition. In particular, the compositions described herein are useful for removing urushiol after it has contacted the skin. The compositions include granules or other scrubbing means to reach the urushiol in the skin, a mixture of surfactants to form a complex with the urushiol, counter-irritants to provide a soothing sensation to the irritated skin, and other functional ingredients to provide additional benefits to the individual who has contacted urushiol.

Botanically derived anti-irritants for prophylactic and therapeutic treatment of adverse skin reactions from application of transdermal or topical drug delivery system, permits the effective administration of a drug from a delivery system in which the drug, of a component of the delivery system comprises a skin irritant; and the delivery systems formed thereby.

A method of image-based quantification for allergen skin reaction includes imaging an area of skin that has been subject to a skin-prick test to produce one or more images of the area. The method includes identifying regions of wheal and/or flare in the one or more images of the area and quantifying weal and/or flare indicators based on the regions identified. The method also includes outputting results of the quantified wheal and/or flare indicators indicative of quantified allergen skin reaction.

A method for treating dermatological conditions as eczema, seborrheic dermatitis, psoriasis and allergic skin reactions such as hives, skin irritations, poison ivy, poison oak, and the like. The method involves applying to the affected area of the skin a few drops of a combination of pheniramine maleate and either naphazoline HCL or phenylephrine HCL and then applying to the same affected area a topical corticosteroid cream, ointment or lotion. The preferred ratio is approximately one drop of solution for every approximately 0.1 grams of topical corticosteroid cream applied to each patch of skin affected with any of the dermatological conditions.

A method of image-based quantification for allergen skin reaction includes imaging an area of skin that has been subject to a skin-prick test to produce one or more images of the area. The method includes identifying regions of wheal and/or flare in the one or more images of the area and quantifying weal and/or flare indicators based on the regions identified. The method also includes outputting results of the quantified wheal and/or flare indicators indicative of quantified allergen skin reaction.

A method of image-based quantification for allergen skin reaction includes imaging an area of skin that has been subject to a skin-prick test to produce one or more images of the area. The method includes identifying regions of wheal and/or flare in the one or more images of the area and quantifying weal and/or flare indicators based on the regions identified. The method also includes outputting results of the quantified wheal and/or flare indicators indicative of quantified allergen skin reaction.

A method of image-based quantification for allergen skin reaction includes imaging an area of skin that has been subject to a skin-prick test to produce one or more images of the area. The method includes identifying regions of wheal and/or flare in the one or more images of the area and quantifying weal and/or flare indicators based on the regions identified. The method also includes outputting results of the quantified wheal and/or flare indicators indicative of quantified allergen skin reaction.

The invention discloses a medical modularized wristband. The medical modularized wristband comprises a main wristband body and a plastic wristlet, and a modularized main control circuit board is arranged in the main wristband body; the modularized main control circuit board is provided with a basic module; the basic module comprises a main control chip, a GPS, a gyroscope, a triaxial accelerationsensor, an ultraviolet sensor, an optic heart rate sensor, a body temperature sensor, a blood oxygen sensor, a noninvasive blood sugar sensor, a galvanic skin reaction sensor and a wireless charging module. The main wristband body is subjected to modularized design, has the waterproof function, and can be disinfected for recycling, the plastic wristlet is in split and cooperative use with the mainwristband body, one person corresponds to one wristlet, and the color corresponds to the nursing level. The medical modularized wristband overcomes the defects in existing medical wristbands; the electronically-informationized intelligent medical wristband is provided to be directly worn by a patient, and more medical information of the patient can be centralizedly collected; through a digital information mode, the real-time state of the patient is monitored, and the medical nursing quality is improved.

The invention belongs to the field of daily use chemical products and particularly relates to a natural herbal whitening mask and a preparation method thereof. According to the invention, natural Chinese herbal medicines including semen coicis, spreading hedyotis herb, salvia miltiorrhiza and bletilla striata are taken as the core to perform reasonable compatibility on effective purified components, and the invented formula has the synergism that the four source medicines are complementary and collaborative; both the main and the auxiliary components of the formula are made from natural animals and plants and do not contain chemosynthesis components, hormone, heavy metal or any Western medicine component, so that the mask is gentle and not irritative in cutaneous reaction and has the medical functions of whitening relatively well, removing acne and freckles, keeping moisture and the like.

Provided are an LED-based skin treatment system capable of performing a skin treatment in consideration of individuals' respective skin properties and a reaction of skin to a change in a patient's emotional state by using an LED light source, and a method thereof. The LED-based skin treatment system includes a skin diagnosis unit ascertaining a patient's skin properties and an extent of a skin reaction to a change in a patient's emotional state by using multiple sensors, and diagnosing a skin lesion and an extent thereof and a skin lesion occurrence location; a skin treatment unit controlling an output state of an LED light source according to the skin lesion and the extent thereof and the skin lesion occurrence location; and a hardware control unit driving the multiple sensors and the LED light source.

The present invention relates to a traditional Chinese medicinal preparation (heat-clearing, blood-cooling and body fluid-promoting beverage) for relieving head or neck tumor radiation therapy side effect: mainly comprising stomatitis, neck skin reaction, hematology variation (mainly indicating leucocyte decreasing), pharynx and esophagus mucosa injury and salivary gland change and etc. It is composed of heat-clearing and antitoxic, blood-cooling and stasis-eliminating, qi-invigorating and body fluid-promoting, spleen and stomach conciliating traditional Chinese medicine, with monarch,minister,assistant and guide to process reasonable compatibility, its medicine constitution according to their weight ratio is: scutellaria ( fried with alcohol) 10 to 15 gram, honeysuckle 10 to 15 gram, forgythia fruit 10 to 15 gram, rehmanniae radix 13 to 18 gram, red sage root 10 to 15 percent, radix paeoniae rubrathe 10 to 15 gram, Chinese angelica 8 to 10 gram, ginseng 6 to 10 gram, Schisandra chinensis 5 to 8 gram, atractylodes rhizome 8 to 10 gram, raw glycyrrhiza 8 to 12 gram. By clinical experiment, effect is obvious. It has characteristics for reducing injury of radiation ray to around normal tissue, promoting around normal tissue repairing, relieving pain caused by radiotherapy side reaction, ensuring radiotherapy successful accomplishment.

The invention discloses a preparation method and application of a novel C19-diterpene alkaloid separated from buttercup Aconitum plant Aconitum taronense. By using the root of Aconitum taronense as a raw material, the novel C19-diterpene alkaloid taronenine A is separated and identified by using an acid water penetrating method, a solvent extraction method, column chromatography on silica gel and a spectroscopy method, in vitro anti-inflammatory experiments indicate that the compound has an obvious effect for inhibiting lipopolysaccharide mediated mouse macrophage RAW 264.7 from releasing skin reaction factor interleukin-6, and the foundation is established for developing novel anti-inflammatory drugs from the plants.

The invention relates to a cemented carbide composition producing method for precious metal, which includes a titanium nitride component contained therein and shows excellent workability, corrosion resistance, reduction in weight and other desirable mechanical properties, as well as the low amount of nickel used as a metallic binder and an aluminum oxide coating helps to suppress potential negative skin reactions.

The invention discloses a tuberculin micro-needle patch as well as a preparation method and application thereof. The tuberculin micro-needle patch is prepared by the following steps: adding a micro-needle raw material solution, which is prepared by mixing tuberculin, a degradable material and sterile water, into a micro-needle template, wherein the concentration of the tuberculin is 20IU/ml to 200IU/ml and the mass percentage of the degradable material is 10 percent to 20 percent; after carrying out centrifuging treatment, removing part of the raw material on a needle hole of a micro-needle; adding a degradable material solution with the concentration of 5 percent to 10 percent; carrying out the centrifuging treatment again; putting the mixture into a drying oven and drying; then de-molding. The tuberculin micro-needle patch disclosed by the invention can be adhered to an adhesive tape and is directly stuck to skin through the adhesive tape so as to replace traditional injector intradermal vaccination; the total content of the tuberculin in the micro-needle patch is 0.05IU. The inoculation operation is simple and convenient and professional persons are not needed; the dosage of medicines is few and a phenomenon that bad skin response is easily generated by an injection skin test is avoided.

The pharmaceutical composition is useful for treating epithelial tumors in a subject and contains at least two antigens and a pharmaceutically acceptable carrier, where each of the antigens induces or is capable of inducing a cutaneous delayed type hypersensitivity (DTH) response in the subject. This composition is particularly useful in treating epithelial tumors, such as warts or verrucae, that are induced by or related to papillomavirus. Antigens useful in the present pharmaceutical composition are anergy panel antigens, such as killed mumps virus, candida extract, trichophyton extract or comparable antigenic extracts. An additional pharmaceutical composition, also useful for treating epithelial tumors, contains at least one antigen that induces or is capable of inducing a cutaneous DTH response in a subject, at least one cytokine or colony stimulating factor and a pharmaceutically acceptable carrier. Kits containing these pharmaceutical compositions are useful for this immunotherapy.

A system, a method, and an apparatus are described herein for determining skin test sensitivities. A first skin test to evaluate a patient's skin reaction to one or more allergens may he performed. After measurements are taken of any reactions to the first skin test, a second skin test may be performed based on the results of the first skin test. Based on the results of the second test, an appropriate treatment endpoint for the patient may be determined. A computer-implemented method may be used for determining skin test sensitivities that may guide a user through one or more appropriate test selection and treatment endpoint determinations.

The invention discloses a whitening anti-inflammatory composition. The whitening anti-inflammatory composition comprises a siegesbeckia orientalis extract and tranexamic acid, wherein the weight ratioof the siegesbeckia orientalis extract to the tranexamic acid is 1:(2-12). Essence prepared from the whitening anti-inflammatory composition meets the requirements on the content of microorganisms and the content of lead, mercury, cadmium, arsenic, phenol, hydroquinone and dioxane in (Safety and Technical Standards for Cosmetics 2015). Through a skin closed type photopatch test, no adverse skin reaction is caused, and whitening anti-inflammatory composition has good mechanical stability, has excellent whitening, brightening, anti-inflammatory, soothing and repairing functions, and does not cause adverse reactions such as redness, swelling and allergy.

An objective of the present invention is to provide a skin ageing preventing composition that contains dehydrogenated abietic acid as an active ingredient and consequently has an outstanding effect in promoting skin cell and collagen production while not giving rise to any adverse skin reactions. Also, an objective of the present invention is to provide a method for preventing skin ageing by using the composition containing dehydrogenated abietic acid as an active ingredient.

The invention provides a medicine for treating chemotherapy induced hand-foot syndromes and targeted therapy induced hand-foot skin reactions and a preparation method thereof. The medicine is prepared from aqueous extract of 5-60 parts by weight of milkvetch roots and 5-30 parts by weight of radix angelica sinensis, extract of 5-30 parts by weight of herba geranii and 5-30 parts by weight of radix arnebiae seu lithospermi, and 45-55wt% ethyl alcohol water solution extract of 5-30 parts by weight of safflower. The medicine for treating chemotherapy induced hand-foot syndromes and targeted therapy induced hand-foot skin reactions has the functions of tonifying qi and promoting blood circulation and removing toxins and promoting granulation, and can achieve the satisfactory effect of effectively treating chemotherapy induced hand-foot syndromes and targeted therapy induced hand-foot skin reactions.

An human keratinocyte cell line immortalized by means of at least one functional tumor gene of retroviral origin characterised in that it is (1) non-tumorigenic, (2) conserves the capacity for differentiation and for the expression of proteins and of enzymes expressed by normal differentiated keratinocytes even after an elevated number of passages in culture, and (3) forms a stratified and polarised epithelium having a stratum corneum ortho-keratinocyte, if cultivated in an organo-typical culture in a medium without serum and without a layer of nourishing cells. An improved process to immortalize human skin cells to obtain immortalized keratinocytes is characterised in that it comprises the following steps: (i) isolating a sample of human skin; (ii) preparing the sample of skin for in vitro culture; (iii) obtaining keratinocytes from this prepared sample of human skin and seeding in a growth medium without serum with said keratinocytes, on culture plates provided with a coating comprising fibronectin, collagen type I and SAB, which facilitate the fixation and the growth of cells; (iv) replacing the medium in a way sufficient to obtain an optimal confluent growth of cells in culture, continuously maintaining the coating of the plate; (v) transferring keratinocytes into a selection medium without serum on culture plates coated previously in a similar manner; (vi) infecting keratinocytes using functional tumor genes of at least two different retrovirus; (vii) transferring the resulting immortalized keratinocytes to a proliferation medium suitable for the proliferation of immortalised keratinocytes on culture plates coated in a similar way; (viii) transferring the resulting proliferated keratinocytes into a differentiation medium having a high content of calcium on culture boxes coated in a similar way. Use of keratinocytes for immunological, pharmacological, photo- and chemical-toxigological analyses of skin reaction and for expression of heterologous genes and for the construction of artificial skin.