Traditional Chinese medicine composition for treating premature ovarian failure as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating premature ovarian failure. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 8-20 parts of radix rehmanniae preparata, 6-10 parts of fructus corni, 10-30 parts of Chinese yam, 10-15 parts of fructus lycii, 6-10 parts of tortoise-plastron glue, 6-10 parts of deer-horn glue, 10-25 parts of semen cuscutae, 6-10 parts of radix cyathulae, 10-15 parts of fructus psoraleae, 10-15 parts of herba taxilli, 10-15 parts of radix dipsaci, 6-10 parts of ginseng, 10-30 parts of radix astragali, 6-10 parts of rhizoma atractylodis macrocephalae, 10-15 parts of radix angelicae sinensis, 10-15 parts of radix paeoniae alba, 6-10 parts of pericarpium citri reticulatae and 6-10 parts of radix glycyrrhizae preparata. The traditional Chinese medicine composition for treating premature ovarian failure can effectively inhibit apoptosis of granulosa cells, promote follicular maturation and improve ovarian reserve capacity, and is high in safety.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically discloses a traditional Chinese medicine composition for treating premature ovarian failure, a preparation method and application thereof. Background technique [0002] Premature ovarian failure (POF) refers to clinical symptoms such as amenorrhea, infertility, hypoestrogen, and elevated gonadotropin levels caused by ovarian follicle depletion in women before the age of 40. At present, the incidence of POF is 1% to 3%, which is increasing year by year and tends to be younger. Even in women <20 years old, the incidence rate is as high as 0.1%, which seriously affects women's reproductive health and physical and mental health. With the implementation of the national two-child policy, the number of women who are clinically willing to have a second child has increased dramatically. Although many young women are of childbearing age, many reasons cause low ovari...

AI Technical Summary

Problems solved by technology

[0003] Modern medicine mainly uses hormone replacement therapy to treat premature ovarian failure. Although it is effective, it cannot be cured. Ovarian function cannot be restored after drug withdrawal, and the risk of breast cancer, endometrial cancer, and thrombotic diseases increases.

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