Medicine for dropping off drug and its preparing process

A technology of medicine and traditional Chinese medicine, which is applied in the preparation of detoxification medicine, and extracts the total alkaloids in Teng teng, which can solve the problems of uncertain drug content, huge prescriptions, and unsuitability for industrial production.

Inactive Publication Date: 2002-07-24
东方药林药业有限公司
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Problems solved by technology

In the aspect of prevention and treatment of drug dependence and withdrawal, some Chinese medicine compound prescriptions used for drug rehabilitation in China also use Caulis sinensis as one of the components of the prescription. It affects the clinical curative effect, the prescription is huge, the preparation process is complicated, the drug content is uncertain, and it is not suitable for industrial production

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Embodiment Construction

[0034] A kind of drug used for detoxification according to the present invention is the total alkaloids of C. chinensis extracted from the traditional Chinese medicine C. chinensis; Alkaline, tetrandrine, bisinomenine, tetrahydroepiperberine, photostephanine and other active ingredients.

[0035] The method for preparing the total alkaloids of C. chinensis comprises the following steps:

[0036] 1. Heat and extract Qingfengteng with acid water twice, each time for 2-3 hours;

[0037] 2. Discard the medicinal residues, combine the two water extracts, add alkali to alkalinize, extract with chloroform, recover the solvent, concentrate under reduced pressure, and dry at low temperature to obtain the crude product of the total alkaloids of C. sinensis;

[0038] 3. Decolorize and purify the crude product of the total alkaloids of C. chinensis through activated carbon to obtain the fine product of the total alkaloids of C. chinensis;

[0039] 4. Make various oral preparations from ...

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Abstract

A medicine for dropping off drug is prepared from caulis sinomenii through thermal extracting in acidic water twice for 2-3 hr each time, filtering to obtain liquid, adding alkali, extracting with chloroform, recovering solvent, vacuum concentrating and low-temp drying to obtain total sinoacutine. Its advantages are stable curative effect and simple preparing process.

Description

technical field [0001] The invention relates to a medicine for detoxification by using traditional Chinese medicine and its preparation, in particular to a method for extracting total alkaloids in Caulis chinensis and its application in the preparation of detoxification medicine. technical background [0002] The treatment of opioid dependence with traditional Chinese medicine is the characteristic and advantage of our country. Traditional Chinese medicine mainly uses compound prescriptions of traditional Chinese medicine in the treatment of this aspect. Traditional Chinese medicine strengthens the body and expels evil spirits, regulates the whole body, treats both symptoms and root causes, and has the characteristics of low toxicity and no addiction, which are incomparable to Western medicine. The multi-target effect of traditional Chinese medicine compound may be better than the single-target effect of Western medicine in some aspects to solve the complex neural mechanism...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/445A61K31/4738A61P25/26C07G5/00
Inventor 莫志贤邓宝养邓虹珠王彩云
Owner 东方药林药业有限公司
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