Composition of medication for treating high blood pressure

Abstract

A composite medicine for treating hypertension contains diuretic, a Ca-contained component and accessory which is acceptable in pharmacy, wherein the weight ratio between the diuretic and the Ca-contained component is in the range of 1:10-2000. The diuretic is chosen from furosemidum, ethacrynic acid, bumetanide, torasemide, hydrochlorothiazinde, chlorothiazide, hygroton, metolazone, quinethazone, triamterene, amiloride, spirolactone or acetazolamide, the Ca-contained component is chosen from shell, keel, inorganic Ca salt, organic Ca salt, etc, wherein the shell comprises concha margaritiferallsta, oyster, concha haliotidis or activative product calcium oxide; inorganic Ca salt and organic Ca salt comprise calcium chloride, Ca carbonate, Ca phosphate, Ca citrate, Ca lactate, Ca gluconate or Ca L-threonate .The composite medicine is capable of decreasing blood pressure by rapidly reducing blood volume, wherein the Ca-contained component can restrain the level of booster factors in body to enhance depressurization effects of the diuretic.

Description

technical field [0001] The present invention relates to a pharmaceutical composition, more specifically, the present invention relates to a pharmaceutical composition for treating hypertension. Background technique [0002] Hypertension is one of the most common cardiovascular diseases at present. It is mainly manifested clinically by increased systemic arterial pressure, often accompanied by various complications such as stroke, myocardial infarction, heart failure, coronary heart disease, and diabetes. Europe and North America are high incidence areas of hypertension. Surveys show that the prevalence of hypertension among adults in my country is 18.8%. It is estimated that the number of patients nationwide is 160 million, an increase of more than 70 million compared with 1991. The prevalence of hypertension in rural areas is rising rapidly, and the gap between urban and rural areas is not obvious. Generally speaking, the life expectancy of hypertensive patients is 15-20 y...

AI Technical Summary

Problems solved by technology

However, there are the following problems: first, the main pathogenic factors of most diseases are unknown; second, most diseases have more complications; third, even if the etiology is known, it is almost impossible for a chemical component to inhibit all causes

However, as hypertension is a disease with uncertain etiology, the cure rate of drugs targeting one or more effects of one etiology or mechanism of action is relatively low. Usually, the cure rate of one drug is about 40-50%, and poor prognosis

In recent years, although there are many new antihypertensive drugs with good curative effect and few side effects, the blood pressure control rate can only reach 50-60%

Images