5 results about "Blood pressure drop" patented technology

The invention relates to the technical field of data processing, and discloses a method and system for predicting a hypotension risk in dialysis based on machine learning. The method comprises the following steps: calculating an ultrafiltration rate-blood pressure decreasing amplitude coupling coefficient by collecting ultrafiltration rate, blood flow volume, transmembrane pressure and blood pressure data in a dialysis process, obtaining a dialysis tolerance index in combination with a vascular compliance parameter, and constructing a stage weighting function according to dialysis duration to determine a weight coefficient of each period; and performing weighted calculation with individual baseline dialysis tolerance to set a personalized risk threshold value, and establishing a sliding window prediction mechanism to predict the probability of occurrence of hypotension in the future. The problems that a static prediction mode cannot adapt to dynamic changes in the dialysis process and is lack of personalized risk assessment are solved, and the accuracy and timeliness of hypotension risk prediction in dialysis are improved.

The invention discloses an intelligent adjusting device for postural hypotension, and relates to the field of blood pressure adjustment, and the device comprises a blood pressure monitoring module which is used for detecting the blood pressure of a lower limb artery area in real time to obtain real-time blood pressure data; the self-adaptive adjusting module is used for dynamically adjusting the pressure applied to the artery area of the lower limb according to the real-time blood pressure data. Through the synergistic effect of real-time monitoring and dynamic adjustment, an active and intelligent blood pressure adjustment mechanism is constructed, blood pressure changes can be automatically responded without frequent manual intervention, the timeliness and accuracy of blood pressure adjustment are improved, the falling risk caused by sudden blood pressure drop of a patient is reduced, and the patient is safer in daily activities (such as getting up and walking).

The invention provides a dynamic risk assessment-based postural hypotension intervention system, which comprises a postural monitoring module for acquiring postural information and postural change parameters of a user in real time, and judging whether the user has rapid postural change possibly inducing hypotension or not according to a preset threshold value; the blood pressure monitoring module is used for monitoring blood pressure parameters of the user in real time to judge whether the blood pressure drops abnormally and send an alarm signal; the environment sensing module is used for providing environment factor parameters; the central control unit communicates with the body position monitoring module, the blood pressure monitoring module and the environment sensing module and is used for fusing and processing characteristic parameters collected by all the modules and carrying out risk score R calculation; and the stimulation execution module is used for performing electrical stimulation intervention according to the instruction sent by the central control unit. Through multi-dimensional data fusion, real-time dynamic monitoring and personalized intervention, a complete solution is provided for management of postural hypotension.

The application belongs to the technical field of medicine, and particularly relates to application of acacetin or 6-hydroxyflavone in preparation of anti-angina pectoris drugs, and aims to solve the problems of adverse reactions such as blood pressure drop, reflex tachycardia and the like caused by non-selective vasodilation of existing anti-angina pectoris drugs, wherein the drug improves myocardial blood supply by selectively dilating coronary vessels of the heart, wherein acacetin dilates coronary vessels of the heart by inhibiting cardiac coronary vessel myosin light chain kinase and activating myosin light chain phosphatase, and 6-hydroxyflavone dilates coronary vessels of the heart by inhibiting protein kinase C and enhancing myosin light chain phosphatase activity; and the acacetin or 6-hydroxyflavone significantly reduces the symptoms of myocardial ischemia of rats caused by isopropyl adrenaline, improves characteristic ECG abnormal changes of angina pectoris, does not affect heart rate and systemic blood pressure, and is safer, thereby providing a potential drug selection for anti-angina pectoris treatment.

The subject matter of the present invention is a DPP3 activity inhibitor for use in therapy or intervention in critical patients with reduced blood pressure in order to protect the myocardium and / or prevent myocardial damage.