Composition having effect of modulating autonomic nerves and method of using the same
An autonomic nerve and regulation technology, which is applied in the field of compositions containing seawater mineral components, can solve the problems of no investigation and no relevant reports on regulation, and achieve the effect of alleviating imbalance
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Embodiment 1
[0033] [Example 1] Preparation Example 1 of a composition containing seawater mineral components
[0034] Use the Asahi Kasei electrodialysis device (SV1 / 2 type), carry out electrodialysis treatment to seawater (Japan, Shizuoka Prefecture, Miura Peninsula Misaki Oki) with a depth of 330m, so that the conductivity at the end of the electrodialysis is 12mS / cm, to obtain 1 Mineral water.
[0035] The primary mineral water was subjected to electrodialysis treatment using an Asahi Kasei electrodialysis device (S3 type) so that the conductivity was changed to 6 mS / cm to obtain secondary mineral water. The electrodialysis membranes used in the primary mineral water production and the secondary mineral water production are both Asahi Kasei AC120 type. In addition, at the beginning, the temperature was set at 15°C, the conductivity of the concentrating chamber side was 1.5mS / cm, the circulation flow rate was 1.4L / min, and electrodialysis was performed at a constant voltage of 12.5V. ...
Embodiment 2
[0038] [Example 2] Regulatory effect on autonomic nervous activity
[0039] A test was carried out on 21 adult males, that is, they ingested 1.5 L of the seawater mineral component-containing composition (hardness 330 mg / L) obtained in Example 1 every day for 5 weeks. The electrocardiogram at rest was measured at the beginning and end of its intake, according to the method of Ue, H. et al. (Ue, H. et al., Ann. Noninvasive Electrocardiol., 5: 336-345 (2000)), according to the heart rate The influence on autonomic nervous activity was analyzed by changing power spectrum method, and the influence on myocardial depolarization and repolarization time (RT) was analyzed according to a differential analysis of electrocardiogram.
[0040] The electrocardiogram uses 14-bit A / D conversion to sample at 1024Hz, and the heart rate change obtained from the electrocardiogram is processed by fast Fourier transform for frequency analysis to obtain the heart rate change power spectrum. In order...
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