Water soluble haloanilide calcium-release calcium channel inhibitory compounds and methods to control bone erosion and inflammation associated with arthritides
a technology inhibitory compounds, which is applied in the field of water soluble haloanilide calcium release calcium channel inhibitory compounds and methods to control bone erosion and inflammation associated with arthritis, can solve the problems that none of these drugs are effective at preventing bone erosion, and achieve the effects of reducing inflammation, reducing inflammation, and reducing inflammation
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[0064]The present invention provides a compound that is 3,4-Dichloro-N-methylaniline.
[0065]In another embodiment of this invention, a compound is provided that is 3-[3,4-dichlorophenyl)methylamino]-3-oxopropanoic acid.
[0066]A preferred embodiment of this invention provides a compound that is 3-(3,4-dichloroanilino)-3-oxopropanoic acid.
[0067]In another embodiment of this invention, a compound is provided that is 3,4-dibromo-N-methylaniline.
[0068]Another embodiment of this invention provides a compound that is 3-[3,4-dibromophenyl)methyl amino]-3-oxopropanoic acid.
[0069]In another preferred embodiment of this invention, a compound is provided that is 3-(3,4-dibromoanilino)-3-oxopropanoic acid.
[0070]In another embodiment of this invention, a compound is provided that is selected from the group consisting of 3-(3,4-dichloroanilino)-3-oxopropanoic acid (hereinafter “DCOPA”); N-methyl-DCOPA; N,2-dimethyl-DCOPA; 2-methyl-DCOPA; isobutyl-DCOPA; N-methyl-isobutyl DCOPA; and 3-(3,4-bibromoani...
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