Application of plant pectin in product for treating gout

Abstract

The invention provides a plant pectin tablet product and a preparation method thereof. The plant pectin tablet product comprises plant pectin, maltodextrin, ultrafine rice hull powder, a filler, a disintegrating agent and a lubricant. The pectin tablet prepared by the invention forms a new composition with the effect of treating gout, and opens up a new direction for treatment of gout patients. The raw materials for preparing the composition for treating gout can be used for food, side effects are avoided, the preparation method is simple and easy to implement, and industrial production is facilitated. The plant pectin tablet is a tablet which is small in auxiliary material amount, uniform in pectin dispersion, good in tablet disintegration property, good in tablet stability, high in bioavailability and capable of effectively treating gout. The invention provides the application of the pectin in preparation of the anti-hyperuricemia and anti-gout health-care food, and the resource range of anti-hyperuricemia and anti-gout drugs or health-care food is expanded.

Description

technical field

[0001] The invention belongs to the field of extraction and application of natural product active ingredients, and in particular relates to the application of plant pectin in products for treating gout. Background technique

[0002] Gout is a group of diseases caused by purine metabolism disorders. Its clinical features are hyperuricemia and the resulting gouty acute arthritis recurrent attacks, tophi deposition, tophi chronic arthritis and joint deformities, often involving Kidney, causing chronic interstitial nephritis and uric acid nephrolithiasis. Gout can be divided into primary and secondary categories. Primary gout is caused by congenital purine metabolism disorder and / or uric acid excretion disorder on the basis of excluding other diseases; a small number of primary gout are caused by enzyme defects, often accompanied by hyperlipidemia, obesity, diabetes, Hypertension, arteriosclerosis and coronary heart disease. Secondary ones can be caused by var...

Examples

Embodiment 1

[0028] In parts by weight, it consists of the following raw materials: 450 parts of apple pectin, 50 parts of superfine rice husk powder, 25 parts of maltodextrin, 5 parts of starch, 10 parts of microcrystalline cellulose, 5 parts of silicon dioxide and stearic acid Magnesium 5 parts.

[0029] Preparation:

[0030] a) take by weighing the raw material of recipe quantity (except superfine rice husk powder) and cross 100 mesh sieves, for subsequent use;

[0031] b) Weigh the superfine rice husk powder of the prescription amount, add the raw material powder described in a) while grinding, and fully mix;

[0032] c) passing the mixed powder uniformly mixed in b) through a 100-mesh sieve, and pressing into tablets under a pressure of 1-10KN to obtain a tablet product for treating gout.

Embodiment 2

[0034] In parts by weight, it consists of the following raw materials: 455 parts of citrus pectin, 15 parts of superfine rice husk powder, 25 parts of maltodextrin, 5 parts of starch, 15 parts of microcrystalline cellulose and 5 parts of magnesium stearate.

[0035] The preparation method is the same as in Example 1.

Embodiment 3

[0037] In parts by weight, it consists of the following raw materials: 454 parts of grapefruit pectin, 20 parts of superfine rice husk powder, 25 parts of maltodextrin, 2 parts of starch, 15 parts of microcrystalline cellulose, 1 part of silicon dioxide and stearic acid Magnesium 5 parts.

[0038] The preparation method is the same as in Example 1.

technical field

[0001] The invention belongs to the field of extraction and application of natural product active ingredients, and in particular relates to the application of plant pectin in products for treating gout. Background technique

[0002] Gout is a group of diseases caused by purine metabolism disorders. Its clinical features are hyperuricemia and the resulting gouty acute arthritis recurrent attacks, tophi deposition, tophi chronic arthritis and joint deformities, often involving Kidney, causing chronic interstitial nephritis and uric acid nephrolithiasis. Gout can be divided into primary and secondary categories. Primary gout is caused by congenital purine metabolism disorder and / or uric acid excretion disorder on the basis of excluding other diseases; a small number of primary gout are caused by enzyme defects, often accompanied by hyperlipidemia, obesity, diabetes, Hypertension, arteriosclerosis and coronary heart disease. Secondary ones can be caused by var...

Examples

Embodiment 1

[0028] In parts by weight, it consists of the following raw materials: 450 parts of apple pectin, 50 parts of superfine rice husk powder, 25 parts of maltodextrin, 5 parts of starch, 10 parts of microcrystalline cellulose, 5 parts of silicon dioxide and stearic acid Magnesium 5 parts.

[0029] Preparation:

[0030] a) take by weighing the raw material of recipe quantity (except superfine rice husk powder) and cross 100 mesh sieves, for subsequent use;

[0031] b) Weigh the superfine rice husk powder of the prescription amount, add the raw material powder described in a) while grinding, and fully mix;

[0032] c) passing the mixed powder uniformly mixed in b) through a 100-mesh sieve, and pressing into tablets under a pressure of 1-10KN to obtain a tablet product for treating gout.

Embodiment 2

[0034] In parts by weight, it consists of the following raw materials: 455 parts of citrus pectin, 15 parts of superfine rice husk powder, 25 parts of maltodextrin, 5 parts of starch, 15 parts of microcrystalline cellulose and 5 parts of magnesium stearate.

[0035] The preparation method is the same as in Example 1.

Embodiment 3

[0037] In parts by weight, it consists of the following raw materials: 454 parts of grapefruit pectin, 20 parts of superfine rice husk powder, 25 parts of maltodextrin, 2 parts of starch, 15 parts of microcrystalline cellulose, 1 part of silicon dioxide and stearic acid Magnesium 5 parts.

[0038] The preparation method is the same as in Example 1.