Preparation method of Sanqing tablets

Abstract

The invention belongs to the technical field of biological medicine, and particularly relates to Sanqing tablets and a preparation method thereof. The preparation method of the Sanqing tablet is characterized by comprising the following steps: (1) extracting; ganoderma lucidum, Chinese yam, poria cocos, hawthorn, mulberry, cinnamon, selfheal, coix seeds, gordon euryale seeds and lotus seeds are taken and mixed, a traditional Chinese medicine composition is obtained, ethyl alcohol is added for extraction, and an extract is obtained; (2) tabletting; and adding an additive into the extract, and tabletting to obtain the tablet. The invention has the following advantages: ten traditional Chinese medicinal materials of lucid ganoderma, Chinese yam, poria cocos, hawthorn, mulberry, cinnamon, selfheal, coix seed, gordon euryale seed and lotus seed are selected, and a treatment method of clearing damp, tonifying qi and promoting blood circulation is provided aiming at the characteristic that the etiology and pathogenesis of hypertension, hyperglycemia, hyperlipidemia and hyperuricemia are mainly excessive dampness; the traditional Chinese medicine composition can effectively reduce hypertension, hyperglycemia, hyperlipidemia and / or hyperuricemia.

Description

Technical Field

[0001] The invention belongs to the technical field of biomedicine, and particularly relates to a preparation method of Sanqing tablets. Background Art

[0002] With the continuous improvement of living standards, the number of patients suffering from hypertension, hyperlipidemia, hyperglycemia, hyperuric acid and other diseases caused by obesity is also increasing.

[0003] At present, treatment is mainly carried out through various Western medicines, and each is targeted for treatment. For example, patients with high blood pressure take drugs to lower blood pressure. If a person has both high blood pressure and high blood lipids, he or she takes drugs to lower blood pressure and blood lipids at the same time.

[0004] Traditional Chinese medicine theory points out that diseases should be viewed from a holistic perspective, and should not be treated dialectically based on a single indicator of the human body. Hypertension, hyperlipidemia, hyperglycemia, hyperuricemia and other diseases caused by obesity belong to metabolic syndrome, which is mainly caused by blood viscosity and excessive moisture. Therefore, it is urgent to develop a safe and effective drug for this type of disease. Summary of the invention

[0005] The purpose of the invention is to provide a method for preparing Sanqing tablets.

[0006] To achieve the above purpose, the technical solution adopted by the present invention is:

[0007] A method for preparing Sanqing tablets, characterized in that it comprises the following steps:

[0008] (1) Extraction: Ganoderma lucidum, Chinese yam, Poria cocos, hawthorn, mulberry, cinnamon bark, selfheal, coix seed, Euryale ferox and lotus seed, mix to obtain a Chinese medicine composition, add ethanol for extraction to obtain an extract;

[0009] (2) tableting: adding the extract to the additives and tableting to obtain the product.

[0010] Preferably, the Chinese medicine composition is made of the following raw materials in weight proportions: 5 parts of Ganoderma lucidum, 5 parts of yam, 5 parts of Poria cocos, 5 parts of hawthorn, 3 parts of mulberry, 3 parts of cinnamon bark, 3 parts of Prunella vulgaris, 3 parts of coix seed, 2 parts of Euryale ferox and 2 parts of lotus seeds.

[0011] Preferably, the extraction is carried out by heating ethanol under reflux.

[0012] Preferably, the extraction is carried out by soaking in ethanol at room temperature, concentrating, and then loading on a macroporous adsorption resin.

[0013] Beneficial effects of the present invention:

[0014] (1) The present invention selects ten kinds of Chinese medicinal materials, namely, ganoderma lucidum, yam, poria cocos, hawthorn, mulberry, cinnamon bark, herb, coix seed, euryale and lotus seed, and proposes a treatment method of removing dampness, replenishing qi and promoting blood circulation, aiming at the characteristics that the etiology and pathogenesis of hypertension, hyperglycemia, hyperlipidemia and hyperuricemia are mainly due to excessive dampness. Among them, ganoderma lucidum is used as the main medicine, yam and poria cocos are used as the auxiliary medicine, and hawthorn, mulberry, cinnamon bark, herb, coix seed, euryale and lotus seed are used as auxiliary medicines, so as to achieve the functions of removing dampness, replenishing qi and promoting blood circulation.

[0015] (2) Compared with the method of directly crushing the medicinal materials, the Sanqing tablets prepared by the present invention through different extraction methods require a smaller amount and the effect can remain unchanged. DETAILED DESCRIPTION

[0016] In order to enable those skilled in the art to understand the production process and technical effects of the present invention in detail, the application and technical effects of the present invention are further introduced with specific production examples below.

[0017] Example 1

[0018] A method for preparing Sanqing tablets, characterized in that it comprises the following steps:

[0019] (1) Extraction: Ganoderma lucidum, Chinese yam, Poria cocos, hawthorn, mulberry, cinnamon bark, selfheal, coix seed, Euryale ferox and lotus seed, mix to obtain a Chinese medicine composition, add ethanol for heating and reflux extraction to obtain an extract; the Chinese medicine composition is prepared from the following raw materials in weight: 5 parts of Ganoderma lucidum, 5 parts of Chinese yam, 5 parts of Poria cocos, 5 parts of hawthorn, 3 parts of mulberry, 3 parts of cinnamon bark, 3 parts of selfheal, 3 parts of coix seed, 2 parts of Euryale ferox and 2 parts of lotus seed.

[0020] (2) Tablet pressing: Add the extract to the additive and press into tablets to obtain the product. Specification: 0.4 g / tablet. Usage: 2 times a day, 3 tablets each time.

[0021] Example 2

[0022] A method for preparing Sanqing tablets, characterized in that it comprises the following steps:

[0023] (1) Extraction: Ganoderma lucidum, Chinese yam, Poria cocos, hawthorn, mulberry, cinnamon bark, selfheal, coix seed, Euryale ferox and lotus seed, mix to obtain a Chinese medicine composition, add ethanol to soak at room temperature, concentrate, and then load on D101 macroporous adsorption resin to obtain an extract; the Chinese medicine composition is prepared from the following raw materials in weight: 5 parts of Ganoderma lucidum, 5 parts of Chinese yam, 5 parts of Poria cocos, 5 parts of hawthorn, 3 parts of mulberry, 3 parts of cinnamon bark, 3 parts of selfheal, 3 parts of coix seed, 2 parts of Euryale ferox and 2 parts of lotus seed.

[0024] (2) Tableting: Add the extract to the additives and press into tablets to obtain the product. Specification: 0.4 g / tablet. Take 1 tablet twice a day.

[0025] Comparative Example 1

[0026] Weigh 5 parts of Ganoderma lucidum, 5 parts of Chinese yam, 5 parts of Poria cocos, 5 parts of hawthorn, 3 parts of mulberry, 3 parts of cinnamon, 3 parts of Prunella vulgaris, 3 parts of Coix seeds, 2 parts of Euryale ferox and 2 parts of lotus seeds, crush and pack them into bags. Specification: 10 bags per bag, 6 grams per bag. Usage: Brew one bag with boiling water every day, drink it warm like tea, and brew it multiple times, regardless of the number of times, until it becomes light.

[0027] The effect was verified according to the method in Chinese patent CN115414449A applied for by the inventor on September 30, 2022. For people with "three highs", the preparation method was changed by the present invention, and the consumption can be reduced while maintaining the same effect.

[0028] Comparative case 1

[0029] Li, after stopping using the product of comparative example 1, switched to the product of example 1 or example 2 for 3 days each, and his blood pressure and blood sugar were stable. The blood pressure was stable at 140-150 / 100-110 mmHg, and the fasting blood sugar was stable between 6.5-8.5.

[0030] Comparative Case 2

[0031] Mr. He stopped using the product of comparative example 1 and switched to the product of example 1 or example 2 for 3 days each, and his blood pressure stabilized at 110-125 / 75-85 mmHg, without dizziness or headache.

[0032] Comparative Case 3

[0033] Zhang, after stopping using the product of comparative example 1, switched to using the product of example 1 or example 2 for 3 days each, his blood pressure stabilized at 129-135 / 80-89 mmHg.

[0034] Compared with the method of directly crushing the medicinal materials, the Sanqing tablets prepared by different extraction methods use less dosage and keep the effect unchanged, which has achieved significant progress. In particular, the method of using D101 macroporous adsorption resin for extraction can better retain the effective parts, greatly reduce the dosage, and maintain the effect.

[0035] Finally, it should be noted that the above embodiments are only used to illustrate rather than limit the technical solutions of the present invention. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that the present invention can still be modified or replaced by equivalents. Any modification or partial replacement that does not depart from the spirit and scope of the present invention should be included in the scope of the claims of the present invention.

Claims

1. A method for preparing Sanqing tablets, characterized in that: The following steps are involved: (1) Extraction: Ganoderma lucidum, Chinese yam, Poria cocos, hawthorn, mulberry, cinnamon bark, selfheal, coix seed, Euryale ferox and lotus seed, mix to obtain a Chinese medicine composition, add ethanol for extraction to obtain an extract; (2) tableting: adding the extract to the additives and tableting to obtain the product.

2. The method for preparing a Sanqing tablet according to claim 1, characterized in that: The Chinese medicine composition is prepared from the following raw materials in weight proportions: 5 parts of ganoderma lucidum, 5 parts of yam, 5 parts of tuckahoe, 5 parts of hawthorn, 3 parts of mulberry, 3 parts of cinnamon bark, 3 parts of selfheal, 3 parts of coix seed, 2 parts of euryale and 2 parts of lotus seed.

3. The method for preparing a Sanqing tablet according to claim 1, characterized in that: The extraction is carried out by heating ethanol under reflux.

4. The method for preparing a Sanqing tablet according to claim 1, characterized in that: The extraction method is to soak the sample in ethanol at room temperature, concentrate the sample, and then load the sample onto D101 macroporous adsorption resin.