2 results about "Antibody screens" patented technology

This invention discloses a shark-derived single-domain antibody that binds to hemoglobin and its application. The nucleotide sequence of the single-domain antibody is labeled SEQ ID NO.1, while the corresponding amino acid sequence is recorded as SEQ ID NO.2. The shark-derived single-domain antibody is used to detect hemoglobin concentration. The detection method includes setting up a standard group and a sample group, then adding the shark-derived single-domain antibody to the immunoassay plates of the standard group and the sample group, and measuring the OD of the standard group and the sample group after color development. 450 Value, based on the OD of the standard group 450 Values, plot OD 450 The standard curve is calculated based on the OD value. 450 The standard curve was used to obtain the hemoglobin concentration of the sample group. The single-domain antibody prepared in this invention exhibits good stability, high specificity, and high affinity. The antibody screened in this invention provides a theoretical basis and technical support for the subsequent diagnosis and monitoring of hemoglobin-targeted diseases.

The utility model discloses an antibody screening microporous plate cleaning device, including the cleaning platform, the one side of cleaning platform top is installed for the abutting plate of the antibody screening microporous plate of waiting for cleaning position, the other side of cleaning platform top is installed with the clamping positioning assembly of cooperation with abutting plate, still be installed with the cleaning assembly for the antibody screening microporous plate cleaning of cleaning platform. The utility model discloses through the convenient positioning structure of abutting plate and swing clamp board cooperation, can fixed microporous plate fast and stably, avoids the uneven and damage problem of displacement when cleaning, and the positioning of convenient and the efficient cleaning greatly shorten operating time, improve work efficiency, reciprocating movement of the brush washing assembly and the flushing assembly with the help of electric cylinder, combine electric push rod, brush washing motor and flush pump, realize efficient and thorough rotation and flush and brush, effectively remove the residual in the micropore, ensure microporous plate cleanliness simultaneously, avoid the residual interference follow -up experiment, guarantee experiment accuracy and reliability.