The invention discloses a manual/electric integrated PE ball valve opening and closing device. The manual/electric integrated PE ball valve opening and closing device comprises a support, a first rotation shaft, a power source, a first tooth piece, a second tooth piece, first helical teeth and second helical teeth. The second helical teeth are connected with an output shaft assembly, and the output shaft assembly is connected with a valve element of a PE ball valve through a transmission rod. The transmission rod is parallel to the first rotation shaft, and the other end of the first rotationshaft is connected with the valve rod. At least part of the valve rod stretches out of the outer portion of the support and is used for rotating of the first rotation shaft through manual applicationof external force. The manual/electric integrated PE ball valve opening and closing device is simple in structure, a ball valve can be manually and electrically driven to be opened and closed, the labor field operation can be replaced, the field maintaining and checking operation requirements can be combined, the small-torque manual operation is achieved through an inner mechanism, opening and closing are conducted in a labor-saving manner, the ball valve pipeline convenience, safety and reliability are improved, and the waterproof and anti-explosion characters are good; and the size is small,starting and stopping are efficient, the labor intensity is relieved, the service life is long, and the usage cost is reduced.