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53results about How to "Long-lasting release" patented technology

Compound formula mouth wash of chlorine dioxide, cetylpyridinium chloride and zinc ion and preparation method thereof

InactiveCN101780016ALower toneLighten your breathCosmetic preparationsToilet preparationsSolventZinc Acetate Dihydrate
The invention relates to compound formula mouth wash of chlorine dioxide, cetylpyridinium chloride and zinc ion and a preparation method thereof. The compound formula mouth wash comprises the following main raw materials: chlorine dioxide, cetylpyridinium chloride and zinc ions, wherein a solvent is distilled water; the concentration of the chlorine dioxide is 200-500 ppm; the cetylpyridinium chloride accounts for the mass fraction of 0.05-0.2 percent relative to the compound formula mouth wash; and the zinc ions accounts for the mass fraction of 0.5-1 percent relative to the compound formula mouth wash. The preparation method of the compound formula mouth wash comprises the following steps of: dissolving the cetylpyridinium chloride and zinc acetate into the distilled water; dissolving a menthol crystal into 95 percent of ethanol; adding a menthol crystal and ethanol solution to a water solution for stirring, and simultaneously adding glycerol; additionally dissolving chlorine dioxide powder into the distilled water; adding a chlorine dioxide water solution to the water solution while stirring; uniformly stirring, and adding the distilled water to obtain the compound formula mouth wash of the chlorine dioxide, the cetylpyridinium chloride and the zinc ions. The invention can effectively inhibit bromopnea for a long time and has fewer side effects and no obvious irritation on an oral mucosa.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Preparation method of carboxymethyl chitosan quaternary ammonium salt/organic rectorite nano composite material and application thereof

The invention provides a preparation method of a carboxymethyl chitosan quaternary ammonium salt/organic rectorite nano composite material and an application thereof. The carboxymethyl chitosan quaternary ammonium salt/organic rectorite nano composite material comprises the basis components of carboxymethyl chitosan quaternary ammonium salt and organic rectorite, and is generated by intercalating the carboxymethyl chitosan quaternary ammonium salt layer between the organic rectorite layers, wherein the distance between the intercalated organic rectorite layers is 4.2-4.72 nm. The preparation method comprises the following steps: dropwise adding the carboxymethyl chitosan quaternary ammonium salt solution of a certain concentration to the organic rectorite aqueous suspension under the condition of stirring at 70-80 DEG C, and then freezing and drying to obtain the nano composite material carboxymethyl chitosan quaternary ammonium salt/organic rectorite. The nano composite material can be used as a drug carrier, has the advantages of both the carboxymethyl chitosan quaternary ammonium salt and the organic rectorite, the drug control-release capability of the nano composite material is superior to that of the single carboxymethyl chitosan quaternary ammonium salt, and the heat resistance of the nano composite material is also significantly improved compared with that of the carboxymethyl chitosan quaternary ammonium salt.
Owner:SOUTH CHINA UNIV OF TECH

Doxycycline-hyclate-carried GTR/GBR composite membrane and preparation method thereof

The invention discloses a doxycycline-hyclate-carried GTR (Guide Tissue Regeneration)/GBR (Guide Bone Regeneration) composite membrane and a preparation method thereof and belongs to the technical field of medicines. The GTR/GBR composite membrane adopts a three-layer structure, wherein the upper surface layer, the lower surface layer and the sandwich layer are all manufactured through sequence electrospinning; the upper surface layer and the lower surface layer are prepared from a natural polymer material and a mixed solution through which the polymer material is synthesized; the sandwich layer is a membrane layer prepared from a doxycycline-hyclate-carried solution through which the polymer material is synthesized. The uniaxial sequence electrospinning method is adopted to prepare the composite membrane adopting the three-layer structure, so that the medicine entrapment efficiency of fibers is improved, the preliminary burst effect of a medicine is reduced/eliminated, and continuously slow release of the medicine is realized. The two surface layers of the three-layer medicine-carried composite membrane can not only serve as porous barriers to control the medicine release rate so as to realize continuously slow release of the medicine but also prevent direct contact between the medicine and tissues to improve the compatibility between the tissues and the membrane so as to be more conducive to tissue repair and regeneration.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Negative oxygen ion functional coating, as well as preparation method and application

The invention discloses a negative oxygen ion functional coating, a preparation method and an application, comprising 3 to 5 parts of tourmaline powder, 1 to 3 parts of graphene oxide, 1 to 2 parts of nano-titanium oxide, 15 to 20 parts of gypsum powder, and diatom powder 30-50 parts of at least one of clay or montmorillonite, and 10-20 parts of at least one of styrene-acrylic emulsion, pure benzene emulsion or water-based polyurethane. The preparation process of the paint raw material of the present invention is simple, and only needs to be pulverized and ground to a specified fineness; the painting process is simple, and no large-scale engineering construction equipment is required; while improving the durability and decoration of the expanded perlite external wall insulation board, it also It can release negative oxygen ions, play the ecological effects of haze reduction, sterilization and air purification, etc., and enrich the performance of the external wall insulation board material; it is prepared into a water-based paint, which has green environmental protection and energy-saving effects compared with traditional oil-based paints; the present invention The produced coating releases a negative oxygen ion concentration of 6000Ions/cm within 14 days 3 above.
Owner:ANHUI MINGYUAN NEW BUILDING MATERIAL TECH CO LTD

Multifunctional negative-ion dry powder paint

The invention belongs to the technical field of paints, and particularly relates to a multifunctional negative-ion dry powder paint. The multifunctional negative-ion dry powder paint is prepared from,by mass, 8-15% of calcined shell powder, 25-30% of ash calcium powder, 10-15% of diatomite, 20-30% of ground calcium carbonate, 2-5% of titanium powder, 1-1.5% of talcum powder, 1-2% of kaolin, 0.8-3% of nanometer titania, 1-3% of negative ion powder, 6-8% of far infrared powder, 0.7-1% of white carbon black, 0.4-0.8% of a cellulose-based surfactant, 0.7-1.5% of redispersible latex powder and 0.03-0.07% of starch ether, wherein the sum of all the components is 100%. The multifunctional negative-ion dry powder paint has the advantages that the paint is capable of efficiently absorbing formaldehyde and other harmful gases and naturally and durably releasing negative ions, excellent in ultraviolet resistance, mould resistance and sterilizing capacity, good in breathability, capable of adjusting the humidity of indoor air and the like, and a coating has high strength and toughness, high rigidity, and a highly bright surface and is fine, smooth, and resistant to washing; the negative-ion dry powder paint integrates multiple functions, is safe, harmless and environmentally friendly, construction is facilitated, polishing links are not needed, and the health of builders is facilitated.
Owner:深圳锦家安科技有限公司

Preparation and application of carbon nano tube-containing thermo-sensitive type gel entrapping for indissolvable drug

The invention discloses preparation and application of carbon nano tube-containing thermo-sensitive type gel entrapping for an indissolvable drug. The preparation method comprises the steps of: 1, preparing a poloxamer solution with a volume ratio of 10-40 percent and a chitosan solution with a volume ratio of 0.1-1 percent, mixing the two solutions in a volume ratio of 1:1 to obtain poloxamer / chitosan thermo-sensitive type gel; 2, mixing 0.01-0.1g of carbon nano tube with 20mL of poloxamer / chitosan thermo-sensitive type gel obtained in the step 1, carrying out high-speed shearing to obtain carbon nano tube-containing poloxamer / chitosan thermo-sensitive type gel; and 3, after dissolving the indissolvable drug in a treatment effective dose in a solvent and mixing with the carbon nano tube-containing poloxamer / chitosan thermo-sensitive type gel obtained in the step 1, shearing at a 2000-5000r / min, freeze-drying to obtain nano particles with particle sizes of 400-600nm. The preparation method has the advantages of simpleness in operation, developed process and high yield; and the prepared thermo-sensitive gel is low in critical micelle concentration, is strong in adhering force with focus tissues, high in drug loading capacity, long in drug sustained release time and high in drug effective utilization rate, and is applied to oral administration and injection administration.
Owner:GUILIN UNIVERSITY OF TECHNOLOGY

LDH (Layered Double Hydroxides) supermolecular assembly type aspirin sustained release tablet and preparation method thereof

The invention relates to an LDH (Layered Double Hydroxides) supermolecular assembly type aspirin sustained release tablet, wherein three levels of supermolecules consisting of dextran, layered double hydroxides and aspirin are used as a medicine barrier, hydroxypropyl methylcellulose is used as a material of a gel skeleton, and the sustained release tablet is prepared by carrying out direct tablet compressing on powder. Auxiliary materials adopted by the LDH supermolecular assembly type aspirin sustained release tablet are good in liquidity, the sustained release tablet can be prepared by carrying out direct tablet compressing on the powder, the process is simple and fast and the cost is low; DET (Dextran)-LDH (Layered Double Hydroxides)-ASP (Aspirin) three-level supermolecule assembly isadopted to overcome the defects of acid dissolution and easiness in sudden release of LDH-ASP so that the system biocompatibility is improved, and by cooperative control of HPMC (Hydroxypropyl Methylcellulose)-DET-LDH, the sustained release performance is obviously improved; and compared with traditional aspirin sustained release tablets with organic auxiliary materials, the LDH supermolecular assembly type sustained release tablet has special cytobiology advantages, relatively high bioavailability, obvious releasing effect and specially sustained transferring and releasing process.
Owner:NINGXIA MEDICAL UNIV

Pioglitazone hydrochloride gastric residential sustained release tablet and preparation method thereof

A pioglitazone hydrochloride gastric residential sustained release tablet adopts pioglitazone hydrochloride as a raw material and is prepared by the following components by weight percent: 10-20% of the pioglitazone hydrochloride, 50-80% of gel formed polymer, 9-30% of foaming agent and the balance of other pharmaceutic adjuvants. The tablet has the advantages that after entering in gastric juice via oral administration, the tablet floats on the gastric juice, is not influenced by gastric emptying, enables drugs to reach absorption sites to be absorbed in a solution state as much as possible, improves bioavailability and prolongs drug action time; the tablet can realize slow and durable release, better absorption effect after administration, steady blood concentration and few administration times; and as the pioglitazone hydrochloride is a weak base salt, and the solubility thereof in an acidic condition is higher than the solubility thereof in a neutral environment or a basic environment, the tablet in the invention can improve the in-vivo dissolution performance of the pioglitazone hydrochloride, and realizes durance release and absorption of the drugs in stomach so as to improve the bioavailability of the drugs.
Owner:QINGDAO HUANGHAI PHARM CO LTD

Filtering material capable of releasing ecological negative ions and preparation method thereof

ActiveCN109499184AThere will be no phenomena such as excessive radioactivityGood release effectHuman health protectionDispersed particle filtrationEmulsionAdhesive
The invention relates to the field of filtering materials, and discloses a filtering material capable of releasing ecological negative ions and a preparation method thereof. A main body of the filtering material is an air or water body filtering substrate which is loaded with nanometer negative ion powder and is made of a macromolecular material. The preparation method comprises the following steps of (1) mixing negative ion powder, an inorganic dispersant and deionized water, and grinding at high speed, so as to obtain stable dispersing liquid containing the nanometer negative ion powder; (2)adding the stable dispersing liquid into a water-based adhesive, stirring at high speed, and emulsifying, so as to obtain an opened-pore water-based adhesive emulsion containing the nanometer negative ion powder; (3) adopting a gap type spot-spray flow technology, and performing scattering type spot-spray flow operation on the filtering substrate multiple times, so as to obtain the filtering substrate loaded with the nanometer negative ion powder; (4) curing the filtering substrate, so as to obtain the filtering material. The filtering material has the advantages that the immobilizing property is efficient, the load is not liable to fall off, and the release amount of ecological negative oxygen ions can reach 25000 per square centimeter.
Owner:ZHEJIANG SCI-TECH UNIV

Herba cistanches and cynomorium songaricum health-care sustained-release capsule

The invention relates to a health-care capsule, and in particular relates to a herba cistanches and cynomorium songaricum health-care sustained-release capsule which can be accurately controlled in taking amount, ensures a nourishing effect, is easily absorbed by human bodies and has a wide application scope. The capsule comprises a protection shell and a content, wherein the content is medicinal micro-pellets which are prepared from the following medicines in parts by weight: 15-25 parts of herba cistanches, 15-25 parts of cynomorium songaricum, 18-22 parts of dragon bones, 18-22 parts of poria, 15-20 parts of fructus mori, 15-20 parts of lycium chinense, 10-20 parts of dioscorea opposite, 10-20 parts of Chinese foxglove, 5-10 parts of China dodder and 1-5 parts of fructus schisandrae chinensis. The medicinal micro-pellets are water-honeyed pills with the diameter of 1-5mm. The protection shell is prepared from polished round-grained rice, wherein 1% of salt is added according to mass percentage. The capsule has the beneficial effects that the capsule can be accurately controlled in taking amount, has a large body application scope, obvious health care and health maintenance effects, a durable release function, equilibrium absorption and functions of nourishing liver and kidney as well as other visceral organs, is low in cost and convenient to take and does not have a peculiar smell.
Owner:叶文明

Microencapsulated selenium-enriched fertilizer for basal application of rice and preparation method of microencapsulated selenium-enriched fertilizer

The invention discloses microencapsulated selenium-enriched fertilizer for basal application of rice. The microencapsulated selenium-enriched fertilizer comprises a core material and a wall material. The weight ratio of the core material to the wall material is (70-80): (20-30). The core material comprises selenium fertilizer, sulfate, nitrogenous fertilizer, potassic fertilizer, phosphate fertilizer, biological bacteria, peat and microelement additives. The wall material comprises modified rice residue albumen. The invention further discloses a preparation method of the microencapsulated selenium-enriched fertilizer for basal application of the rice. The microencapsulated selenium-enriched fertilizer has the advantages that a microencapsulation technology is adopted, the modified rice residue albumen serves as the wall material, and the sulfate is added into the core material to be applied with the selenium fertilizer, so that selenium absorption of rice roots and upward transfer of selenium are improved, fixation of the selenium is avoided, and selenium utilization rate is increased; fertilizer efficiency of microcapsules is released slowly, and accordingly, crop's need for nutrition in each growth stage is met.
Owner:安徽康坶国际化肥股份有限公司

Preparation process for slow-release type chlorine dioxide microcapsule antibacterial film

ActiveCN107353611AHas a strong antibacterial effectAntibacterial effect is longChlorine dioxideFiltration
The invention discloses a preparation process for a slow-release type chlorine dioxide microcapsule antibacterial film. The preparation process comprises the following operation steps: 1, preparing microcapsule powder: dissolving gelatin in a stable chlorine dioxide aqueous solution to obtain a water-phase solution; dissolving PLA in dichloromethane to obtain an oil-phase solution; and adding a Span-80 emulsifier into the oil-phase solution, then adding the water-phase solution and liquid paraffin, performing stirring, performing vacuum filtration, and performing lyophilization to obtain the chlorine dioxide microcapsule powder; and 2, preparing the antibacterial film: adding the chlorine dioxide microcapsule powder, an activator and a plasticizer to a film-forming base material PLA, performing uniform stirring, allowing the stirred materials to stand for 60min for eliminating bubbles, and performing coating by a flat-board coating machine to form the film. According to the invention, the antibacterial film prepared by adopting the method has the advantages of wide raw material sources, safety and sanitation, biodegradability and the like, and the antibacterial film has powerful antibacterial effects, a long slow-release period, and wide application prospects in a freshness-retaining respect of fresh foods.
Owner:GUANGXI UNIV

Preparation and application of carbon nano tube-containing thermo-sensitive type gel entrapping for indissolvable drug

The invention discloses preparation and application of carbon nano tube-containing thermo-sensitive type gel entrapping for an indissolvable drug. The preparation method comprises the steps of: 1, preparing a poloxamer solution with a volume ratio of 10-40 percent and a chitosan solution with a volume ratio of 0.1-1 percent, mixing the two solutions in a volume ratio of 1:1 to obtain poloxamer / chitosan thermo-sensitive type gel; 2, mixing 0.01-0.1g of carbon nano tube with 20mL of poloxamer / chitosan thermo-sensitive type gel obtained in the step 1, carrying out high-speed shearing to obtain carbon nano tube-containing poloxamer / chitosan thermo-sensitive type gel; and 3, after dissolving the indissolvable drug in a treatment effective dose in a solvent and mixing with the carbon nano tube-containing poloxamer / chitosan thermo-sensitive type gel obtained in the step 1, shearing at a 2000-5000r / min, freeze-drying to obtain nano particles with particle sizes of 400-600nm. The preparation method has the advantages of simpleness in operation, developed process and high yield; and the prepared thermo-sensitive gel is low in critical micelle concentration, is strong in adhering force with focus tissues, high in drug loading capacity, long in drug sustained release time and high in drug effective utilization rate, and is applied to oral administration and injection administration.
Owner:GUILIN UNIVERSITY OF TECHNOLOGY

Composition for treating oral diseases and preparation method of composition

The invention discloses a composition for treating oral diseases and a preparation method of the composition. The composition is mainly prepared from the following components: chlorine dioxide, cetyl pyridinium chloride and zinc ions, wherein the solvent is distilled water, the concentration of chlorine dioxide is 200-500 ppm, the weight of cetyl pyridinium chloride accounts for 0.05-0.2 % of that of compound mouthwash, and the weight of zinc ions accounts for 0.5-1 % of that of the compound mouthwash. The preparation method of the composition comprises the following steps: dissolving cetyl pyridinium chloride and zinc acetate in the distilled water, dissolving menthol in 95% alcohol, adding the menthol alcohol solution into an aqueous solution, carrying out stirring, and meanwhile, adding with glycerinum; taking chlorine dioxide powder, dissolving the chlorine dioxide powder in distilled water, adding the chlorine dioxide aqueous solution into aqueous solution under stirring, carrying out uniform mixing, and adding with distilled water, thus obtaining the composition for treating oral diseases. The composition has the advantages that the mouth odor can be inhibited for a long term, the side effects are small, and no obvious irritation is caused to the oral mucosa.
Owner:江彩莲

Mouthwash for effectively inhibiting bad breath and preparation method thereof

The invention relates to mouthwash for effectively inhibiting bad breath and a preparation method thereof. Main components of raw materials of the mouthwash comprise chlorine dioxide, cetyl pyridiniumchloride and zinc citrate, wherein a solvent is distilled water and the concentration of the chlorine dioxide is 200 to 500ppm; the mass percent content of the cetyl pyridinium chloride accounts for0.05 to 0.2 percent of the compound formula mouthwash; the mass percent content of the zinc citrate accounts for 0.5 to 1 percent of the compound formula mouthwash; the preparation method of the mouthwash comprises the following steps: dissolving the cetyl pyridinium chloride and the zinc citrate into the distilled water and dissolving menthol crystal into 95 percent ethanol; adding a menthol crystal ethanol solution into a water solution and stirring; meanwhile, adding glycerol; taking the chlorine dioxide powder and dissolving into the distilled water; adding a chlorine dioxide water solution into the water solution; adding the chlorine dioxide solution and stirring; uniformly mixing and adding the distilled water to obtain the mouthwash for effectively inhibiting the bad breath. The mouthwash provided by the invention has the advantages that the bad breath is effectively inhibited for long time, side effects are relatively small and the mouthwash has no obvious irritation on oral mucosa.
Owner:罗爱莲

Slow-release Fenton-like system based on immobilized enzyme and method for in-situ remediation of groundwater pollution by slow-release Fenton-like system

The invention discloses a slow-release Fenton-like system based on an immobilized enzyme, and provides a method for in-situ remediation of groundwater pollution. The method mainly comprises the following steps: 1) selecting a central well and a plurality of peripheral chemical adding wells in a pre-remediated groundwater pollution area; 2) adding green rust into the chemical adding wells, then pumping water from the central well, recharging the water into underground water through the chemical adding well, and continuously pumping water until green rust appears; and 3) arranging an immobilized enzyme reactor in each chemical adding well, conducting aerating, introducing a glucose solution, pumping a small amount of water in the central well, recharging the water into underground water through the chemical adding wells, and pumping water until the concentration of effluent pollutants reaches the standard. The slow-release Fenton-like system has a pH range close to the environment where underground water is located, lasting slow release of free radicals and controllability of a degradation area can be achieved in the whole process, other pollutants cannot be introduced into the underground water, and non-toxicity and harmlessness can be achieved.
Owner:WUHAN UNIV OF TECH

Preparation method of capsule fiber and capsule fiber

The invention provides a preparation method of a capsule fiber and the capsule fiber and aims at improving the functional characteristic of an existing capsule fiber, wherein the preparation method comprises the following steps: preparing microfine medical stone powder sieved by using a sieve smaller than 450 meshes from medical stone; uniformly mixing pollen particles and the microfine medical stone powder according to the weight ratio of 3:2 to obtain aromatic powder; mixing an acidic dye with carbon cellulose under a vacuum environment to prepare a capsule core; blending the aromatic powderand liquid water into an aromatic liquid within the range of 40-55 DEG C; impregnating the capsule core into the aromatic liquid for 20-30 min, then, taking out and drying the capsule core to preparea functional capsule core; wrapping a hydrophilic colloid and the capsule core to form a microcapsule, adding the microcapsule into a molten polyester chip, and carrying out uniform mixing to obtaina spinning raw material; adding the spinning raw material into a spinning machine for high-speed spinning to prepare nascent fiber; and sizing the nascent fiber by using a parallel drawing machine toobtain the capsule fiber. The preparation method has the technical advantage that additional functions of the capsule fiber can be kept for a long time.
Owner:北京麻世纪麻业科技发展有限公司
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