Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of Fructus Forsythiae in preparing anti-tumor chemotherapeutic sensitivity intensifying attenuating medicine

An anti-tumor and drug technology, applied in the pharmaceutical field, can solve problems such as increasing the efficacy of chemotherapy drugs

Inactive Publication Date: 2008-01-09
WUHAN UNIV
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

, but there are no relevant reports about the combined use of forsythia and chemotherapeutic drugs to increase the curative effect of chemotherapeutic drugs and reduce the toxicity of chemotherapeutic drugs. The present invention provides forsythia alcohol extract as a new chemotherapeutic drug sensitizer for anti-tumor adjuvant therapy

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of Fructus Forsythiae in preparing anti-tumor chemotherapeutic sensitivity intensifying attenuating medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: The composition is made of 1000 grains of forsythia alcohol extract 1-100 grams and cellulose 400-499 grams. The preparation method is as follows: granulating the forsythia alcohol extract and cellulose, and then pressing into tablets or filling capsules, and each grain (tablet) contains 1-100 mg of the forsythia alcohol extract.

Embodiment 2

[0015] Example 2: Forsythia alcohol extract composition is prepared by adding 1-100 grams of Forsythia alcohol extract to 1 liter of water for injection and subpackaging it into 1000 sticks. The preparation method is as follows: dissolve the forsythia alcohol extract in water for injection, add to 1 liter, sterilize, and pack separately. Each bottle contains 1-100mg of forsythia alcohol extract.

[0016] The alcoholic extract of Forsythia in the above examples can be obtained by conventional extraction methods; for example, add 3 times the volume of Forsythia 70% ethanol to reflux for 2 hours, repeat 3 times, combine the extracts, reflux and concentrate to obtain the alcoholic extract of Forsythia.

[0017] Study on synergistic anti-tumor effect of active components of forsythia in vitro

[0018] experimental method

[0019] Experimental group

[0020] CY+DDP (cisplatin+cyclophosphamide) treatment group

[0021] (1) normal control group (control); (2) model group (model, C...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention relates to an application of Chinese medicinal material forsythia fruit in preparation of anti-tumor chemotherapeutic sensitivity-enhancing and attenuating medicine. It is characterized by that the invented medicine can be made up by using forsythia fruit alcohol extract and medicinal carrier and / or excipient through a certain preparation process.

Description

technical field [0001] The present invention relates to the application of forsythia, in particular to the application in the field of pharmacy. Background technique [0002] According to the statistics of the World Health Organization, in the 1980s, the number of cancer patients in the world was about 7 million people every year, and the number of cancer deaths was about 5 million people every year. By the 1990s, the number of cancer cases in the world was about 10 million per year, and about 7 million people died every year. The harm of cancer in the world is becoming more and more serious. In the next decade, cancer will replace cardiovascular disease as the first disease that seriously endangers human health. In the mid-1970s in my country, the National Cancer Prevention and Research Office of the Ministry of Health organized a national retrospective survey of cancer deaths. At that time, cancer incidence was about 900,000 people per year, and cancer deaths were about ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61P35/00A61P39/02A61K131/00
Inventor 丁虹陆伟根高天芸
Owner WUHAN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com