Immunochromatographic test paper and preparation method for simultaneously detecting torch infection

Abstract

The invention provides an immunochromatographic test paper for simultaneously detecting ToRCH infection and a preparation method thereof. It includes a substrate, a chromatographic membrane is bonded to the substrate, at least two specific antigen detection lines are coated and fixed on the chromatographic membrane, a colloidal gold conjugate pad and a sample pad are sequentially glued to the lower end of the chromatographic membrane, and the upper end of the chromatographic membrane It is an absorbent pad, the detection lines are arranged in a staggered manner on the chromatographic membrane, and the absorbent pad has an identification area corresponding to the specific detection line on the chromatographic membrane. This test strip is used to simultaneously detect whether a person has ToRCH specificity IgM or IgG infection. This test strip not only overcomes the shortcoming that a single test strip can only detect one pathogen at a time, but also avoids that the complex formed by the front detection line will affect the subsequent detection when several items are tested on a chromatographic strip at the same time. , is greatly limited in sensitivity, the test strip has the advantages of simple operation, fast, sensitive, no need for special equipment, intuitive observation results, etc., which greatly facilitates clinical testing and screening.

Description

Background technique [0001] The invention relates to a chromatography test paper and a preparation method thereof, in particular to an immunochromatography test paper for simultaneous detection of ToRCH infection and a preparation method. Background technique [0002] ToRCH is a combination of the English name prefixes of Toxoplasma gondii (Tox), Rubella Virus (Rubella Virus, RubV), Cytomegalovirus (CMV), and Herpes simplex Virus (HSV), which can cause congenital Intrauterine infections and perinatal infections cause perinatal malformations. [0003] ToRCH infection in pregnant women has no clinical symptoms and is a hidden infection. The diagnosis of intrauterine infection in the fetus should first determine whether the pregnant woman is infected. ToRCH infection in pregnant women poses a great threat to prenatal and postnatal care and population quality. Therefore, ToRCH screening during pregnancy is Very necessary. At present, hospitals and family planning service departments ...

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is exactly to overcome the problem that its sensitivity is not high when carrying out multiple pathogen detection on a test paper at present, provide a kind of immunochromatographic test paper and preparation method that have advantages such as simple in structure, easy to use, high sensitivity to detect ToRCH infection simultaneously

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