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Compound prescription for defending and protecting hepar as well as preparation technique thereof

A production process and formula technology, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, drug combinations, etc., can solve the problems that it is difficult to meet the health care needs of the people, and it is not suitable for non-hepatitis patients for long-term use, so as to achieve adjuvant treatment of virus Hepatitis, liver protection, and fatty liver prevention effects

Inactive Publication Date: 2008-05-21
BEIJING ZHONGKE YONGHE PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are also some drugs for protecting the liver and treating hepatitis, but these drugs have many shortcomings, are not suitable for non-hepatitis patients to take for a long time, and are difficult to meet the health care needs of the people's health

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Southern Schisandra 800kg White Peony 300kg Milk Thistle 400kg Corn Starch 10kg

[0028] Grind Schisandra chinensis into coarse powder, heat and reflux extract with 6 times the amount of 80% ethanol for 3 times, each time for 1.5 hours, combine the extracts, filter, recover ethanol, concentrate to a relative density of 1.30-1.35 extract (50-60°C thermal measurement), vacuum-dried, and crushed through a 80-mesh sieve. spare. Milk thistle and white peony are decocted with 8-10 times the amount of water three times, followed by 2 hours, 1.5 hours, and 1 hour, filtered, and the filtrate is concentrated to a relative density of 1.15-1.20 extract (heat test at 50-60°C) , spray-dried. The above two medicinal powders are added with cornstarch according to the proportion of the formula, and mixed evenly. Take a small amount of capsules and measure the disintegration time limit, which should be within 20 minutes. Check hygiene, measure moisture. Pack after passing.

Embodiment 2

[0030] Southern Schisandra 1300kg White Peony 500 parts Milk Thistle 600kg Corn Starch 20kg

[0031] Grind Schisandra chinensis into coarse powder, heat and reflux extract with 6 times the amount of 80% ethanol for 3 times, each time for 1.5 hours, combine the extracts, filter, recover ethanol, concentrate to a relative density of 1.30-1.35 extract (50-60°C thermal measurement), vacuum-dried, and crushed through a 80-mesh sieve. spare. Milk thistle and white peony are decocted with 8-10 times the amount of water three times, followed by 2 hours, 1.5 hours, and 1 hour, filtered, and the filtrate is concentrated to a relative density of 1.15-1.20 extract (heat test at 50-60°C) , spray-dried. The above two medicinal powders are added with cornstarch according to the proportion of the formula, and mixed evenly. Take a small amount of capsules and measure the disintegration time limit, which should be within 20 minutes. Check hygiene, measure moisture. Pack after passing.

Embodiment 3

[0033] Southern Schisandra 1050kg White Peony 400kg Milk Thistle 500kg Corn Starch 15kg

[0034] Grind Schisandra chinensis into coarse powder, heat and reflux extract with 6 times the amount of 80% ethanol for 3 times, each time for 1.5 hours, combine the extracts, filter, recover ethanol, concentrate to a relative density of 1.30-1.35 extract (50-60°C thermal measurement), vacuum-dried, and crushed through a 80-mesh sieve. spare. Milk thistle and white peony are decocted with 8-10 times the amount of water three times, followed by 2 hours, 1.5 hours, and 1 hour, filtered, and the filtrate is concentrated to a relative density of 1.15-1.20 extract (heat test at 50-60°C) , spray-dried. The above two medicinal powders are added with cornstarch according to the proportion of the formula, and mixed evenly. Take a small amount of capsules and measure the disintegration time limit, which should be within 20 minutes. Check hygiene, measure moisture. Pack after passing.

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PUM

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Abstract

The invention discloses a composite formula used for protecting liver, which is prepared by fructus schisandrae sphenantherae extract, white paeony root extract and Milk Thistle extract and adding with certain supplementary materials, wherein, the extraction preparation technologies of the Chinese traditional medicine include: the fructus schisandrae sphenantherae is crushed into rough powder; the rough power is heated, refluxed and extracted by 60 to 80 percent of alcohol in the quantity of 6 folds for 3 times with 1.5 hours for one time; the extracting solution is combined, the alcohol are filtered and recycled; the filtered solution is concentrated into an extract with relative density of 1.30 to 1.35 (thermally measuring in 50 to 60 DEG C); the extract is dried in vacuum, ground and screened with 80 meshes. The Milk Thistle and the white paeony root are boiled for three times in water of 8 to 10 folds, the lasting time respectively is 2 hours, 1.5 hours and 1 hour; then the boiled solution is filtered, and the filtering solution is concentrated into an extract with relative density of 1.15 to 1.20 (thermally measuring in 50 to 60 DEG C), and the extract is sprayed and dried. The formula has the major effects of protecting liver, preventing fatty liver, having curing and health effect on the chemical liver injury (including poisoning, and overdrink of alcohol, etc.), having adjuvant treatment on the virus hepatitis, alleviating the deterioration of chronic hepatitis and liver cirrhosis.

Description

technical field [0001] The invention relates to a compound formula for protecting the liver and belongs to the technical field of functional health food. Background technique [0002] Fatty liver refers to the pathological changes caused by excessive accumulation of fat in liver cells due to various reasons. Due to various reasons, the fat metabolism function of the liver is impaired, resulting in a dynamic imbalance of lipids, and excess fat accumulates in the liver cells. If the accumulated fat (mainly triglycerides) exceeds 5% of the wet weight of the liver, or In histology, more than 50% of the liver cells are fatty, which is called fatty liver. It is a disease with a good prognosis, but long-term fatty liver (especially alcoholic fatty liver) will be complicated by liver fibrosis, and even develop into cirrhosis. Functional failure is life-threatening. [0003] With the rapid development of my country's economy, the improvement of people's living standards, and the a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P1/16
Inventor 鄢良张韬程华
Owner BEIJING ZHONGKE YONGHE PHARMA TECH
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