Chinese medicine color spectrum fingerprint pattern characteristic digitalization and full-qualitative full-quantitative quality control method

A quality control method and technology of fingerprints, which are used in measuring devices, instruments, scientific instruments, etc.

Inactive Publication Date: 2008-09-24
SHENYANG PHARMA UNIVERSITY
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AI Technical Summary

Problems solved by technology

At the same time, the quality control method of gold qualitative and quantitative similarity of chromatographic fingerprints of traditional Chinese medicines was disclosed

Method used

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  • Chinese medicine color spectrum fingerprint pattern characteristic digitalization and full-qualitative full-quantitative quality control method
  • Chinese medicine color spectrum fingerprint pattern characteristic digitalization and full-qualitative full-quantitative quality control method
  • Chinese medicine color spectrum fingerprint pattern characteristic digitalization and full-qualitative full-quantitative quality control method

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Embodiment Construction

[0033] 1. Use the digital control method of chromatographic fingerprints of traditional Chinese medicine, that is, use 37 characteristic parameters to reveal the shallow information characteristics of chromatographic fingerprints of traditional Chinese medicines from multiple sides and all-round. The quality control of Chinese herbal medicines, Chinese herbal extracts and herbal preparations, and herbal medicines is realized by compiling computer software using the above indicators.

[0034] 2. With η, A 0 , γ, δ, τ, β, N, W, F, Fr, I, Ir and other indicators alone or in part to control the production quality of Chinese herbal medicines, Chinese herbal extracts and Chinese herbal preparations, with 37 characteristic parameters or some of them Compile computer software.

[0035] 3. The macroscopic content similarity R%, content similarity Q%, corrected content similarity Q F %, projected content similarity C%, quantitative similarity P%, modulus length percentage W%, average ...

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Abstract

The invention discloses a digital control method of super-information characteristics of traditional Chinese medicine chromatographic fingerprint, and 37 characteristic indicators are combined with the computer software technology to be used for the production quality control of traditional Chinese medicine materials, traditional Chinese medicine extracts and traditional Chinese medicine preparations. The invention simultaneously discloses an overall qualitative and overall quantitative quality control method of the traditional Chinese medicine chromatographic fingerprint, which uses the ratio qualitative similarity SF', Q percent of the content similarity, QF percent of the correction content similarity, C percent of the projection content similarity, P percent of the quantitative similarity, W percent of the norm length percentage, M percent of the average weight percentage, MF percent of the correction average weight percentage, d percent of the Euclidean distance percentage, Delta C percent of the projection content similarity error and other indicators and is further combined with the computer software technology to be used for the production quality control of the traditional Chinese medicine materials, the traditional Chinese medicine extracts, the traditional Chinese medicine preparations and botanical drugs. The digital control method is used for the evaluation of the fingerprint of the traditional Chinese medicine or the traditional Chinese medicine preparations and the confirmation and the evaluation of the test conditions, thus leading the test results to have quantitative reference indicators under the different conditions, which has great practicality.

Description

Technical field: [0001] The invention belongs to the technical field of medicine, specifically, it is a theoretical control method for the quality control technology of chromatographic fingerprints of traditional Chinese medicines, that is, a digital control method of chromatographic fingerprints of traditional Chinese medicines and a quality control method of full qualitative and full quantitative similarity. Background technique: [0002] Traditional Chinese medicine is a treasure with independent intellectual property rights in Chinese medicine. After joining the WTO, it is the most competitive variety. The bottleneck restricting my country's traditional Chinese medicine industry is the quality control of traditional Chinese medicine, which has seriously affected the export of traditional Chinese medicine. Fingerprint is currently internationally recognized as the most effective and reliable control technology to comprehensively reflect the quality of natural medicines. T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/86
Inventor 孙国祥毕开顺
Owner SHENYANG PHARMA UNIVERSITY
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