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Medicinal dripping pill for treating hypertension

A high blood pressure and drug technology, applied in the field of drug drop pills for the treatment of high blood pressure, can solve the problems of high blood pressure control can not meet people's wishes, limit clinical application, etc., achieve therapeutic effect without side effects, significant therapeutic effect, improve solubility and The effect of dissolution rate

Active Publication Date: 2009-11-18
BEIJING WBL PEKING UNIV BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effects of antihypertensive drugs on metabolism and target organ damage are still controversial, and most of them have certain side effects, which partially limit their clinical application.
Make the control of high blood pressure unsatisfactory

Method used

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  • Medicinal dripping pill for treating hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Red yeast rice 3kg Uncaria 5kg Dendrobium 3kg

[0034] The above-mentioned medicines are made into water extract dry cream respectively according to the conventional process, and mixed to obtain a composition intermediate; according to the weight ratio, the composition intermediate: PEG 4000 = Add PEG at a ratio of 1:3.0 4000 , the preparation method of dropping pills is: after heating and melting polyethylene glycol, add the composition intermediate, mix well, keep warm at 75±2°C; drop into the coolant with a dropping pill machine, and the temperature of the coolant is 20±2°C 2°C, after molding, take out the dropping pills, remove the coolant on the surface, and pack them.

Embodiment 2

[0036] Red yeast rice 2kg Uncaria 7kg Dendrobium 4kg

[0037] The above-mentioned medicines are made into alcohol extract dry paste respectively according to the conventional process, and mixed to obtain a composition intermediate; according to the weight ratio, the composition intermediate: PEG 6000 = Add PEG at a ratio of 1:3.5 6000, the preparation method of dropping pills is: after heating and melting polyethylene glycol, add the composition intermediate, mix well, keep warm at 75±2°C; drop into the coolant with a dropping pill machine, and the temperature of the coolant is 20±2°C 2°C, after molding, take out the dropping pills, remove the coolant on the surface, and pack them.

Embodiment 3

[0039] Red yeast rice 4kg Uncaria 4kg Dendrobium 2kg

[0040] The above-mentioned medicines are jointly extracted according to the conventional process to make a dry paste of the extract obtained by water extraction and alcohol precipitation through a macroporous resin adsorption column, and mixed to obtain a composition intermediate; according to the weight ratio, the composition intermediate: PEG 4000 = Add PEG at a ratio of 1:2.5 4000 , the preparation method of dropping pills is: after heating and melting polyethylene glycol, add the composition intermediate, mix well, keep warm at 75±2°C; drop into the coolant with a dropping pill machine, and the temperature of the coolant is 20±2°C 2°C, after molding, take out the dropping pills, remove the coolant on the surface, and pack them.

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Abstract

The invention discloses a medicinal dripping pill for treating hypertension, which consists of composition intermediates of red infested rice, uncaria, dendrobium and polyethylene glycol. The intermediates of the dripping pill are prepared from dry paste of extract of bulk drug prepared by the prior method. The medicinal dripping pill has remarkable treatment effect and no side effects.

Description

technical field [0001] The invention relates to a medicine drop pill, in particular to a medicine drop pill for treating hypertension. Background technique [0002] Hypertension is a systemic disease caused by the interaction of polygenic inheritance, the environment and various risk factors. The worldwide incidence rate is as high as 10-20%, and it is a major disease that endangers human health. my country is a country with a high incidence of essential hypertension. In 1991, according to the original hypertension standard census, the prevalence rate of hypertension over 15 years old in my country was 13.58%. According to this incidence rate, there are about 200 million hypertensive patients in my country. If diagnosed according to existing criteria, there will be more patients with hypertension. However, the phenomenon of "three highs and three lows" exists in the prevalence of hypertension in my country, namely: high prevalence rate, high disability rate and high mort...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61K9/20A61K47/34A61P9/12A61K47/10
Inventor 段震文郭树仁
Owner BEIJING WBL PEKING UNIV BIOTECH
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