Pharmaceutical composition for preventing and/or treating bone loss

A pharmaceutical composition, a technology for bone loss, applied in the directions of pharmaceutical combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2011-08-31
KO PHARML
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern medicine is mainly estrogen replacement therapy to the treatment method of postmenopausal osteoporosis, but long-term use has certain side effect (ColditzGA, HankinsonSE, HunterDJ. : ameta-analysis.ObstetGynecol, 1995,85:304-313), therefore, there is an urgent need for a pharmaceutical composition that can be used to prevent and / or treat bone loss

Method used

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  • Pharmaceutical composition for preventing and/or treating bone loss
  • Pharmaceutical composition for preventing and/or treating bone loss
  • Pharmaceutical composition for preventing and/or treating bone loss

Examples

Experimental program
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Embodiment

[0043] The pharmaceutical composition of the present invention comprises 30 kilograms of Radix Glycyrrhizae (purchased from Jinbaoan Trading Co., Ltd.), 60 kilograms of black soybeans (purchased from Ditai Trading Co., Ltd.), 10 kilograms of Fructus Cnidii (purchased from Yicheng Trading Co., Ltd.), antlers ( Purchased from Ditai Trading Co., Ltd.) 8 kg composition. First, heat the licorice root to 100°C, extract it with water, and take 150 liters of the extract. Then soak the black beans and Cnidium Fructus in 30% ethanol for 20 hours, then heat to 80°C for extraction, and combine with the licorice extract. 30 liters of liquid, add antler powder to the concentrated liquid and dry at 60°C for 48 hours. The dried product is pulverized and then granulated to form a dosage form.

[0044] 2. Animal experiments are familiar with the steps of technicians

[0045] Eight-week-old female rats of the Sprague-Dawley breed were used in the National Center for Experimental Animal Breedi...

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PUM

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Abstract

The invention provides a pharmaceutical composition which comprises an effective dose of bergapten and pharmaceutically acceptable carriers or excipients, and the pharmaceutical composition can be used for preventing and / or treating bone loss.

Description

[0001] This application is a divisional application of the Chinese invention application (name of invention: pharmaceutical composition for preventing and / or treating bone loss; filing date: October 18, 2006; application number: 200610135591.9). technical field [0002] The present invention relates to a pharmaceutical composition, and in particular to a pharmaceutical composition for preventing and / or treating bone loss. Background technique [0003] Osteoporosis can be divided into two categories: one is "postmenopausal osteoporosis" caused by the lack of female hormones, which is more common in postmenopausal women; the other is caused by It is caused by aging, which we call "senile osteoporosis", which may occur in both men and women as long as they live old enough. It can be found from clinical research reports that when menopausal women have insufficient secretion of estrogen, the rate of bone loss can be as high as 3% to 5% a year. Accelerated bone loss will lead to ...

Claims

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Application Information

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IPC IPC(8): A61K31/015A61P19/10
Inventor 陈兆祥简美英符文美张金鸣
Owner KO PHARML
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