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Medicinal composition for preventing or treating nonalcoholic steatohepatitis

A steatohepatitis, non-alcoholic technology, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of liver enzyme changes and unsatisfactory effect

Active Publication Date: 2012-08-22
DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effect of treatment is unsatisfactory, especially when NASH is accompanied by changes in liver enzymes and hyperlipidemia.

Method used

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  • Medicinal composition for preventing or treating nonalcoholic steatohepatitis
  • Medicinal composition for preventing or treating nonalcoholic steatohepatitis
  • Medicinal composition for preventing or treating nonalcoholic steatohepatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0119] Embodiment 1: Granules

[0120] Gynostemma 15kg Curcuma 9kg Atractylodes 10kg

[0121] Milk thistle 15kg Alisma 10kg Poria cocos 10kg

[0122] Cassia seed 10kg Salvia miltiorrhiza 15kg White mustard seed 6kg

[0123] Hawthorn 10kg

[0124] The above-mentioned raw materials are added into conventional excipients according to the conventional process to make granules. 10 grams per bag, 2 times a day, 1 bag each time.

Embodiment 2

[0125] Embodiment 2: tablet

[0126] Gynostemma 10kg Curcuma 11kg Atractylodes 7kg

[0127] Milk thistle 20kg Alisma 7kg Poria cocos 12kg

[0128] Cassia seed 7kg Salvia 20kg White mustard seed 4kg

[0129] Hawthorn 12kg

[0130] The above raw materials are added into conventional excipients according to the conventional process to make tablets.

Embodiment 3

[0131] Embodiment 3: capsules

[0132] Gynostemma 20kg Curcuma 7kg Atractylodes 12kg

[0133] Milk thistle 10kg Alisma 12kg Poria cocos 7kg

[0134] Cassia seed 12kg Salvia miltiorrhiza 10kg White mustard seed 8kg

[0135] Hawthorn 7kg

[0136] The above-mentioned raw material drug is added into conventional excipients according to the conventional process to make capsules.

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PUM

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Abstract

The invention discloses a medicinal composition for preventing or treating nonalcoholic steatohepatitis. The composition consists of gynostemma pentaphylla, radix curcumae, rhizoma atractylodis macrocephalae, silybum marianum, rhizoma alismatis, poria cocos, semen cassiae, salvia miltiorrhiza, seman sinapis albae and hawthorn. The medicinal composition disclosed by the invention has the functions of invigorating the spleen, soothing the liver, activating blood and eliminating turbid, and has an obvious effect on preventing or treating nonalcoholic steatohepatitis.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating steatohepatitis, in particular to a pharmaceutical composition for preventing or treating nonalcoholic steatohepatitis. Background technique [0002] Non-alcoholic fatty liver disease (NAFLD) has become one of the common clinical liver diseases and is the primary cause of abnormal serum transaminases. Among them, non-alcoholic steatohepatitis (NASH) is a very important process in the transformation process from non-alcoholic fatty liver (NAFL) to non-alcoholic fatty liver cirrhosis (non-alcoholic cirrhosis). It is one of the important causes of cryptogenic liver cirrhosis. Studies have shown that the prognosis of NASH is poor, about 50% of NASH will develop into liver fibrosis, 15% to 30% will develop into liver cirrhosis, and 3% will develop into liver failure. Therefore, studying the prevention and treatment strategies of NASH is one of the research hotspots in the field of liver di...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/16
Inventor 李军祥
Owner DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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