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Traditional Chinese medicine composition for treating swine toxoplasmosis as well as preparation and application thereof

A technology of toxoplasmosis and its composition, which is applied in the field of traditional Chinese medicine, can solve the problems of drug resistance, human health hazards, and many adverse reactions, and achieve the effects of avoiding veterinary drug residues and social pollution, not easy to relapse, and reasonable prescriptions

Inactive Publication Date: 2013-08-28
JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, sulfonamide chemical drugs are commonly used clinically to treat this disease. Although the treatment has a certain effect, there are also disadvantages such as long treatment cycle, large dose, many adverse reactions, and easy drug resistance. It is also easy to form drug residues, which is extremely harmful to human health.

Method used

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  • Traditional Chinese medicine composition for treating swine toxoplasmosis as well as preparation and application thereof
  • Traditional Chinese medicine composition for treating swine toxoplasmosis as well as preparation and application thereof
  • Traditional Chinese medicine composition for treating swine toxoplasmosis as well as preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Prescription: 30 grams of ground peach blossom; 16 grams of white ox gallbladder; 4 grams of chicken nashu; 5 grams of licorice.

[0050] Concrete preparation process is as follows:

[0051] a. Add distilled water 4 times the total weight of 4 traditional Chinese medicines to the mixed medicinal materials of ground peach blossom, white ox gallbladder, chinna tree, and licorice, soak for 24 hours, decoct 3 times, keep for 0.5 hours after each boil, and combine the decoction and concentrated to a thick form.

[0052] b. Add ethanol with a concentration of 95% to the concentrated solution to adjust the alcohol concentration to 60%, stir and mix well, let it settle for 24 hours, filter, recover ethanol from the filtrate, and add the concentration of the medicinal solution after recovering ethanol to 95% Adjust the ethanol to the alcohol concentration of 75%, stir well, let it stand for 48 hours, filter, recover the ethanol from the filtrate and concentrate it until there i...

Embodiment 2

[0055] Prescription: 50 grams of ground peach blossom; 25 grams of white ox gallbladder; 6 grams of chicken nashu; 2 grams of licorice.

[0056] a. Add distilled water of 3 times the total weight of 4 traditional Chinese medicines to the mixed medicinal materials of ground peach blossom, white ox gallbladder, chinna tree, and licorice, soak for 30 hours, decoct 3 times, keep for 1 hour after each boil, and decoct together liquid and concentrate to a thick form.

[0057] b. Add 90% ethanol to the concentrated solution to adjust the alcohol concentration to 65%, stir and mix well, let it settle for 48 hours, filter, recover ethanol from the filtrate, and add 90% ethanol to the liquid medicine after recovering ethanol Adjust the alcohol concentration to 75% with ethanol, stir well, let it settle for 48 hours, filter, recover the ethanol from the filtrate and concentrate it until there is no alcohol smell, add 2 times the weight of the concentrated dosing solution to the distilled...

Embodiment 3

[0060] Prescription: 60 grams of ground peach blossom; 30 grams of white ox gallbladder; 8 grams of chicken nashu; 4 grams of licorice.

[0061] a. Add 4 times the total weight of 4 traditional Chinese medicines in distilled water to the mixed medicinal materials of ground peach blossom, white ox gallbladder, quinna tree, and licorice, soak for 27 hours, then decoct 3 times, and keep for 1 hour after each boiling, combine the decoction and dry Concentrate to a thick consistency.

[0062] b. Add ethanol with a concentration of 95% to the concentrated solution to adjust the alcohol concentration to 70%, stir and mix well, let it settle for 48 hours, filter, recover ethanol from the filtrate, and add the concentration of the medicinal solution after recovering ethanol to 95% Adjust the ethanol to the alcohol concentration of the liquid medicine to be 80%, stir well, let it settle for 48 hours, filter, recover the ethanol from the filtrate and concentrate it until there is no alco...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating swine toxoplasmosis as well as a preparation and an application thereof. The traditional Chinese medicine composition is liquid medicine prepared by the following steps of: adding distilled water to mix with urena lobata, inula cappa, Cinchona succirubra and liquorice and decoct for 1-3 times, combining decoction, concentrating the decoction to be in a thick state, adding ethyl alcohol with the concentration of 90-95% to regulate the ethyl alcohol concentration to be 60-70%, precipitating, filtering and concentrating filter liquor; adding ethyl alcohol with the concentration of 90-95% into the concentrated filter liquor to regulate the ethyl alcohol concentration to be 75-80%, precipitating, filtering, and concentrating filter liquor; and adding distilled water into the concentrated filter liquor, refrigerating, precipitating, filtering, and concentrating to obtain the liquid medicine. The traditional Chinese medicine composition has a recovery rate to the swine toxoplasmosis being more than 90% and less side effects, and is safe and convenient to use, low in use amount and quick to absorb.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and relates to a traditional Chinese medicine composition for pigs, a preparation method thereof and the application of the traditional Chinese medicine composition in the preparation of Chinese veterinary medicine for treating swine toxoplasmosis. Background technique [0002] Toxoplasmosis is a zoonotic disease, a variety of animals can be the host, the infection rate of both humans and animals is high, among which the infection of pigs is the most common. The pathogen was first discovered in a rabbit in a laboratory in Brazil at the beginning of the last century. In the 1970s, it was discovered in Shanghai, Beijing and other places in my country that the so-called "unknown high fever in pigs" was caused by the pathogen of this disease, thus causing General attention. At present, sulfonamide chemical drugs are commonly used clinically to treat this disease. Although the trea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61P33/02
Inventor 魏宁贺生中刘俊栋曹斌张步彩吴桂银
Owner JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE
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