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Traditional Chinese medicine preparation for treating pediatric epilepsy and preparation method thereof

A traditional Chinese medicine preparation and a technology for epilepsy are applied in the field of traditional Chinese medicine preparations for treating epilepsy in children and the preparation thereof, which can solve the problems of drug dependence, cerebral nerve function damage, toxic and side effects, and reduce drug dependence, resistance to drug resistance, and toxic and side effects. low effect

Inactive Publication Date: 2014-09-17
王智霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although western medicine and western medicine have their advantages in controlling epileptic seizures, too strong inhibitory effect will cause damage to the brain nerve function and have obvious toxic side effects
Such as carbamazepine, epileptamine, etc., generally cannot completely cure epilepsy, and the side effects are large, drug dependence is easy to occur, and it is easy to cause side effects such as mental depression and mental retardation
In addition, often taking antiepileptic western medicine can easily lead to drug resistance. To maintain a certain curative effect, the dose must be increased, which will cause more serious damage.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0054] The present invention also provides a preparation method of the above-mentioned Chinese medicine preparation. When the selected dosage form is a capsule, the preparation method comprises the following steps:

[0055] The first step is to mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 85% to 95% that is 4 to 6 times the mass of the mixture, heat and reflux for 35 to 45 minutes, extract, and filter to obtain the first Extracting solution, filtering the medicinal dregs obtained, then adding ethanol with an alcohol concentration of 85% to 95% relative to the quality of the medicinal dregs, heating and refluxing for 25 to 35 minutes, extracting, filtering to obtain the second extracting solution, and the first The extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0056] In the second step, the dry ...

Embodiment 1

[0070] Embodiment 1 capsule of the present invention

[0071] Take 1000g orange red, 500g ground beetle, 500g Prunella vulgaris, 1000g Jiangxiang, 2000g yellow horn, 1000g jujube, 1000g heterophylla, 2000g earthworm, 2000g Qingdai, 1000g solitary life, 2000g mother-of-pearl, 500g dodder, 2000g pig heart, yam 1000g and forsythia 1000g;

[0072] Its preparation method comprises the following steps:

[0073] The first step is to mix the above-mentioned raw materials and medicinal materials, add ethanol with an alcohol concentration of 90% to 5 times the mass of the mixture, heat and reflux for 45 minutes, extract, filter to obtain the first extract, and then add the medicinal residue obtained by filtering 3 times the mass of ethanol with an alcohol concentration of 90%, heated to reflux for 35 minutes, extracted, filtered to obtain the second extract, combined with the first extract and the second extract, concentrated under reduced pressure to remove the ethanol solvent, dried ...

Embodiment 2

[0076] Embodiment 2 syrup of the present invention

[0077] Take 800g orange red, 400g ground beetle, 400g Prunella vulgaris, 600g Jiangxiang, 1800g yellow horn, 700g jujube, 800g heterophylla, 1700g earthworm, 1600g Qingdai, 600g solitary life, 1900g mother-of-pearl, 400g dodder, 1800g pig heart, yam 700g and 600g forsythia;

[0078] Its preparation method comprises the following steps:

[0079] In the first step, mix yellow horn, heterophylla, earthworm, indigo naturalis, lovage and mother-of-pearl according to the stated ratio, dissolve it in ethanol with an alcohol concentration of 95% which is 5 times the mass of the obtained mixture, and heat to reflux for 5 hours Extract and filter to obtain the first filtrate; dissolve the filter residue again with 90% ethanol with an alcohol concentration of 4 times the mass of the obtained mixture, extract after heating and reflux for 2 hours, and obtain the second filtrate; combine the first For the filtrate and the second filtrat...

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PUM

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Abstract

The invention provides a traditional Chinese medicine preparation for treating pediatric epilepsy and a preparation method thereof. The traditional Chinese medicine preparation comprises the following raw medicines: tangerine peel, ground beeltle, selfheal, lignum dalbergiae odoriferae, mongolian gazelle horn, jujube, heterophylly falsestarwort root, lumbricus, natural indigo, pubescent angelica root, nacre mother, Chinese dodder seed, pork heart, Chinese yam and forsythia. The traditional Chinese medicine preparation provided by the invention has the advantages of fast effect, exact drug efficacy, low toxic and side effects and capability of being safely taken by sick children for a long term and has the beneficial effects that the damage to brain nervous function can be reduced, the drug tolerance has small possibility of producing and the drug dependence is alleviated.

Description

technical field [0001] The invention relates to a medical preparation containing medicinal materials derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating epilepsy in children and a preparation method thereof. Background technique [0002] Epilepsy, commonly known as "shorn horn" or "epilepsy", is a chronic disease in which the sudden abnormal discharge of brain neurons leads to transient brain dysfunction. Due to the different starting sites and transmission modes of abnormal discharges, the clinical manifestations of epileptic seizures are complex and diverse, which can be manifested as paroxysmal motor, sensory, autonomic, conscious and mental disturbances. Epilepsy can occur in all age groups. The incidence of epilepsy in children is higher than that in adults, and the incidence of epilepsy decreases with age. In old age (after the age of 65), the incidence of epilepsy increases again due to the increase of c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61P25/08A61P25/10A61P25/12A61K35/32A61K35/34A61K35/56A61K35/64A61K35/618A61K35/62
Inventor 王智霞
Owner 王智霞
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