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Semen arecae prepareta extractive capable of promoting gastrointestinal motility and preparing method thereof

A technology of gastrointestinal peristalsis and burnt betel nut, which is applied in the field of medicine to achieve the effect of promoting gastrointestinal peristalsis, good safety and effectiveness

Inactive Publication Date: 2013-12-04
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented betelnut extraction has two benefits: one being able to improve gut movements while reducing stomach discomfort caused from traditional methods like catheterization (which may cause complications), and another having potential medical applications such as improving blood circulation during surgery procedures.

Problems solved by technology

The technical problem addressed in this patents relates to improving the performance of traditional chinese herbal remedy containing betelnut extracted from bovitolerma capsules, tablets, liquor buckles, spray solutions, powders, liquid suppositories, creams, gelatin capsule dosages, and other ingredients like sterilizing agents, antiosis substances, antiemezings, carboxytibodies, cytostatic activity suppressive agents, calcium channel blockers, neurologists' syndrome preventives, tranquillizers, narrower range therapies, and others.

Method used

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  • Semen arecae prepareta extractive capable of promoting gastrointestinal motility and preparing method thereof
  • Semen arecae prepareta extractive capable of promoting gastrointestinal motility and preparing method thereof
  • Semen arecae prepareta extractive capable of promoting gastrointestinal motility and preparing method thereof

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Effect test

preparation example Construction

[0028] Preparation of the reference solution Take an appropriate amount of arecoline hydrobromide, accurately weigh it, add mobile phase to make a solution containing 0.1 mg per 1 ml, and obtain (weight of arecoline = weight of arecoline hydrosulfate / 1.5214).

[0029] Preparation of the test solution Take about 0.3g of the powder of this product (passed through a No. 5 sieve), weigh it accurately, put it in a stoppered Erlenmeyer flask, add 50ml of ether, and then add carbonate solution buffer (take 1.91g of sodium carbonate and sodium bicarbonate 0.56g, add water to dissolve into 100ml (to get) 3ml, stand for 30 minutes, shake from time to time; heat to reflux for 30 minutes, separate the ether solution, add to an evaporating dish containing 1ml of phosphoric acid solution (5→1000) medium; add diethyl ether to the residue and heat and reflux extraction twice (30ml, 20ml), each time for 15 minutes, combine the diethyl ether solution and put it in the same evaporating dish, evap...

Embodiment 1

[0038] 1. Add 200g of burnt betel nut, add 10 times the amount of water, extract 3 times, each time for 1.5 hours, combine the extracts, filter, concentrate the filtrate to a clear paste with a relative density of 1.08-1.20, and dry it.

[0039] 2. Add 200g of burnt betel nut, add 10 times the amount of 40% ethanol, extract 3 times, each time for 1.5 hours, combine the extracts, filter, recover the ethanol from the filtrate, concentrate it to a clear paste with a relative density of 1.08-1.20, and dry it.

[0040]3. Add 200g of burnt betel nut, add 10 times the amount of 50% ethanol, extract 3 times, each time for 1.5 hours, combine the extracts, filter, recover the ethanol from the filtrate, concentrate it to a clear paste with a relative density of 1.08-1.20, and dry it.

[0041] 4. Add 200g of burnt betel nut, add 10 times the amount of 60% ethanol, extract 3 times, 1.5 hours each time, combine the extracts, filter, recover the ethanol from the filtrate, concentrate it to a ...

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Abstract

The invention belongs to the field of medicine, and discloses a semen arecae prepareta extractive capable of promoting gastrointestinal motility and a preparing method thereof. The method for preparing the semen arecae prepareta extractive includes the steps of extracting semen arecae prepareta 1-3 times by using 30%-70% ethyl alcohol, wherein each time lasts for 0.5-2h; combining and filtering extracting solutions; obtaining the semen arecae prepareta extractive by concentrating the extracting solutions to be dry. Preparations of the extractive can be obtained by adding proper pharmaceutic adjuvant into the semen arecae prepareta extractive and adopting conventional preparation technologies, and then the oral drug preparations such as tablets, capsules, granules, dripping pills and oral solutions and the injectable drug preparations such as freeze-dried powder and hydro-acupuncture preparations can be obtained. The extractive and the preparations thereof have the significant function of promoting gastrointestinal motility, and as shown in toxicity tests at earlier stages, the emen arecae prepareta extractive is nontoxic and can be prepared into food, health food and drugs.

Description

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Claims

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Application Information

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Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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