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A kind of polymer composite material suitable for bioreactor and preparation method thereof

A high-molecular polymer and bioreactor technology, which is applied in the field of composite materials and their preparation, high-molecular polymer composite materials and their preparation, can solve the problem of low wear resistance, inability to use bioreactor stirring environment, and inability of materials to be used. Casual use and addition, etc., to achieve the effect of excellent wear reduction performance

Active Publication Date: 2015-09-09
成都英德生物医药设备有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Although the composite membrane material in the above patent is suitable for bioreactors, it is only for membrane bioreactors. Its characteristics are mainly manifested in support strength, mechanical stability, high pressure resistance, etc., and its wear resistance is not high, so it cannot be applied to conventional bioreactors. stirring environment
[0009] In summary, the development of high wear-resistant composite materials in bioreactors has its limitations and difficulties. Unknown and unverified materials cannot be used and added casually.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] A polymer composite material suitable for bioreactors, comprising the following raw materials in parts by weight:

[0049] 55 parts of polytetrafluoroethylene

[0050] 10 parts polyetheretherketone

[0051] Polyphenylene 8 parts

[0052] 3 parts polyphenylene ether

[0053] Polyethylene 3 parts

[0054] 3 parts polyamide

[0055] 3 parts of zirconia or silicon nitride.

Embodiment 2

[0057] A polymer composite material suitable for bioreactors, comprising the following raw materials in parts by weight:

[0058] 70 parts of polytetrafluoroethylene

[0059] 15 parts polyetheretherketone

[0060] Polyphenylene 12 parts

[0061] 5 parts polyphenylene ether

[0062] Polyethylene 5 parts

[0063] Polyamide 5 parts

[0064] 5 parts of zirconia or silicon nitride.

Embodiment 3

[0066] A polymer composite material suitable for bioreactors, comprising the following raw materials in parts by weight:

[0067] 62.5 parts of polytetrafluoroethylene

[0068] Polyetheretherketone 12.5 parts

[0069] Polyphenylene 10 parts

[0070] 4 parts polyphenylene ether

[0071] Polyethylene 4 parts

[0072] 4 parts polyamide

[0073] Zirconia or silicon nitride 4 parts.

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PUM

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Abstract

The invention relates to a polymer composite material suitable for a bioreactor and a preparation method thereof, belonging to the technical field of biopharmaceuticals. The composite material of the present invention includes the following raw materials in parts by weight: 55-70 parts of polytetrafluoroethylene, 10-15 parts of polyether ether ketone, 8-12 parts of polyphenylene resin, 3-5 parts of polyphenylene ether, poly 3-5 parts of ethylene, 3-5 parts of polyamide, 3-5 parts of zirconia or silicon nitride. The composite material of the present invention solves the problem that the composite material in the prior art is partially toxic, volatile and decomposed, has poor temperature resistance and corrosion resistance, and is not suitable for bioreactors, and although it is suitable for bioreactors, it is only for membrane bioreactors. The problem of wear resistance is not high, it meets and meets all the performance requirements of the bioreactor in contact with biological products, and has self-lubricating performance, which greatly improves the wear resistance.

Description

technical field [0001] The invention relates to a composite material suitable for a bioreactor and a preparation method thereof, more specifically, the present invention relates to a high molecular polymer composite material suitable for a bioreactor and a preparation method thereof, belonging to the technical field of biopharmaceuticals . Background technique [0002] The materials used in the bioreactor in direct contact with biological products are quite demanding: non-toxic, high temperature resistant, steam sterilization will not decompose, volatilize, age and ooze and fall off; do not react with biological products (biologically inert); Does not inhibit or benefit the growth of organisms (biocompatibility); corrosion resistance (chemical inertness), and does not undergo chemical reactions and changes to frequently used acid-base cleaning fluids and other organic substances. [0003] Therefore, it is very prudent to select its structural materials, and materials cannot...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L27/18C08L61/16C08L67/04C08L71/12C08L23/06C08L77/00C08K3/22C08K3/34
Inventor 马强国
Owner 成都英德生物医药设备有限公司
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