High-molecular polymer composite suitable for bioreactor and method for manufacturing high-molecular polymer composite

Abstract

The invention relates to a high-molecular polymer composite suitable for a bioreactor and a method for manufacturing the high-molecular polymer composite, and belongs to the technical field of biological pharmacy. The composite comprises, by weight, 55-70 parts of polytetrafluoroethylene, 10-15 parts of polyether-ether-ketone, 8-12 parts of polyphenyl ester, 3-5 parts of polyphenyl ether, 3-5 parts of polyethylene, 3-5 parts of polyamide and 3-5 parts of zirconia or silicon nitride. The high-molecular polymer composite and the method have the advantages that problems that parts of existing composites in the prior art are toxic, the existing composites are volatile, are easy to decompose, are poor in temperature resistance and corrosion resistance and are not suitable for bioreactors, or the existing compositions are only suitable for membrane bioreactors and are poor in abrasion resistance are solved; all requirements on the performance of the high-molecular polymer composite which is in contact with biological products in the bioreactor are met, the high-molecular polymer composite has self-lubricating performance, and the abrasion resistance of the high-molecular polymer composite is greatly improved.

Description

technical field [0001] The invention relates to a composite material suitable for a bioreactor and a preparation method thereof, more specifically, the present invention relates to a high molecular polymer composite material suitable for a bioreactor and a preparation method thereof, belonging to the technical field of biopharmaceuticals . Background technique [0002] The materials used in the bioreactor in direct contact with biological products are quite demanding: non-toxic, high temperature resistant, steam sterilization will not decompose, volatilize, age and ooze and fall off; do not react with biological products (biologically inert); Does not inhibit or benefit the growth of organisms (biocompatibility); corrosion resistance (chemical inertness), and does not undergo chemical reactions and changes to frequently used acid-base cleaning fluids and other organic substances. [0003] Therefore, it is very prudent to select its structural materials, and materials cannot...

AI Technical Summary

Problems solved by technology

[0008] Although the composite membrane material in the above patent is suitable for bioreactors, it is only for membrane bioreactors. Its characteristics are mainly manifested in support strength, mechanical stability, high pressure resistance, etc., and its wear resistance is not high, so it cannot be applied to conventional bioreactors. stirring environment

[0009] In summary, the development of high wear-resistant composite materials in bioreactors has its limitations and difficulties. Unknown and unverified materials cannot be used and added casually.