Multifunctional bionic tissue culture device

Abstract

The invention discloses a multifunctional bionic tissue culture device comprising a culture chamber and a sliding column, wherein a liquid inlet hole and a liquid outlet hole are formed in the culture chamber, a built-in bracket assembly is arranged in the culture chamber and comprises a bottom plate, a top plate, an adjusting plate, a movable sliding plate and a plurality of supporting guide upright columns, the upper and lower ends of the supporting guide upright columns are fixedly connected with the top plate and the bottom plate respectively, a positioning trough is formed in the lower half section of each supporting guide upright column, the adjusting plate is blocked in the positioning trough for positioning, the movable sliding plate is in sliding fit with the upper half section of each supporting guide upright column and is connected with the sliding column through an upper pressure head, an upper hook is arranged on the movable sliding plate, a lower pressure head is arranged on the adjusting plate, and a lower hook is arranged on the adjusting plate. The multifunctional bionic tissue culture device is convenient to fix tissues, has a better bionic simulation effect of a physiological environment, is wide in application range, and reduces the production cost.

Description

Technical field [0001] The invention relates to the field of biological tissue engineering preparation devices, in particular to a multifunctional bionic tissue culture device. Background technique [0002] In vitro biomimetic culture of biological tissues refers to the cultivation of tissue engineering tissues constructed using tissue engineering technology under in vitro culture conditions that mimic the physiological environment in vivo to promote tissue engineering tissue structure and function maturity. This kind of bionic cultivation can only be realized with the help of the application of the cultivation room. The bionic simulation of the physiological environment particularly needs to involve two aspects of bionics, namely, the simulation of blood circulation in the medium supply mode, and the simulation of the physiological stress environment and mode in the stress application. Currently, there are two types of more advanced tissue culture chambers used for biological t...

AI Technical Summary

Problems solved by technology

[0006] This kind of bionic tissue culture room can only cultivate one type of tissue, bone tissue or tendon tissue, and cannot be changed according to the needs of culture. Therefore, a large amount of bionic tissue culture room reserves are required, resulting in the vacancy of many bionic tissue culture rooms, which increases the training cost

[0007] The scaffold used to support the biological tissue is fixed on the lower container, and the distance between the scaffold and the stressing device cannot be adjusted, therefore, only bone tissue or tendon tissue with a narrow length range can be cultured, and the application range is too small to adapt to different tissues needs to be cultivated

[0008] The bracket used to support the biological tissue is fixed on the bottom wall of the lower container. When fixing bone tissue or tendon tissue, it is difficult to put the bone tissue in the correct position of the bracket, and it is even more difficult to fix the tendon tissue on the clip of the bracket. If the fixation effect of bone tissue or tendon tissue is not good, it will cause the bone tissue or tendon tissue to fall off during the bionic simulation of the physiological environment, resulting in culture failure

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