Personal care compositions with improved solubility of a solid UV active

A technology of personal care and active substances, applied in skin care preparations, medical preparations containing active ingredients, cosmetics, etc.

Inactive Publication Date: 2014-06-11
THE PROCTER & GAMBLE COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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However, there is still a need for alt

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  • Personal care compositions with improved solubility of a solid UV active
  • Personal care compositions with improved solubility of a solid UV active
  • Personal care compositions with improved solubility of a solid UV active

Examples

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example 1

[0130] Example 1 - The solvency of isosorbide diesters within the scope of the invention was tested relative to two conventional industry standard solvents. Using butylmethoxydibenzoylmethane (i.e. avobenzone, can 1789 commercially available from DSM) as solid UV actives were tested for the solvency of isosorbide dicaprylate, isopropyl lauroyl sarcosinate and C12-15 alkyl benzoate. Various ratios of solute:solvent were prepared by mixing solvent with solid sunscreen (solute) and heating to 70°C. After reaching 70°C, the examples can be mixed for about 10 minutes. The mixture was placed in a covered vial and cooled to storage temperature. Solubility was assessed on samples stored at room temperature for 24 hours after mixing. Solubility was also assessed on samples stored at 5°C for 7 days, followed by equilibration to ambient conditions. The results are shown in Table 1. The data show that the solvency power of isosorbide diester is equivalent to that of the main industr...

example 2

[0134] Example 2 - The solvency of isosorbide diesters within the scope of the invention was tested relative to two conventional industry standard solvents. Use of bis-ethylhexyloxyphenol methoxyphenyl triazine (i.e., betrazinol, can S (commercially available from BASF) were used as solid UV actives to test the solvency of isosorbide dicaprylate, isopropyl lauroyl sarcosinate and C12-15 alkyl benzoate. Various ratios of solute:solvent were prepared by mixing solvent (eg, magnetic stir plate and stir bar) with solid sunscreen (solute) and heating to 70 °C. After reaching 70°C, the examples can be mixed for about 10 minutes. The mixture was placed in a covered vial and cooled to storage temperature. Solubility was assessed on samples stored at room temperature for 24 hours after mixing. Solubility was also assessed on samples stored at 5°C for 7 days, followed by equilibration to ambient conditions. The results are shown in Table 2. The data show that the solvency of isoso...

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Abstract

A personal care composition may have an isosorbide diester having the formula (I): wherein R' and R" are independently selected from a straight or branched C1-30 chain, which may be saturated or unsaturated. The composition may further comprise a solid UV active soluble in the isosorbide diester and a dermatologically acceptable carrier. The personal care composition may be in the form of an emulsion having an aqueous phase comprising water and an oil phase. The oil phase may comprise the isosorbide diester and a solid UV active soluble in the isosorbide diester. In a particular embodiment, the solid UV soluble in the isosorbide diester UV active may be selected from 4-tert-butyl-4'-methoxy dibenzoylmethane, bis-ethylhexyloxyphenol methoxyphenyl triazine, and combinations thereof. Methods of making the aforementioned personal care compositions are disclosed.

Description

technical field [0001] The present invention relates to personal care compositions comprising isosorbide diesters as solvents for solid UV actives. Background technique [0002] A variety of personal care compositions are formulated to act as sunscreens or to provide a secondary benefit of UV protection. UV actives are used to provide such compositions with UV absorbing capability. Many of the more potent UV actives that provide absorption benefits over a broader range of the UV spectrum are solid materials. These solid UV actives need to be dissolved to provide an effective and consumer acceptable composition. For example, solid UV actives such as butylmethoxydibenzoylmethane (i.e. avobenzone) and / or (2-hydroxy-4-methoxyphenyl)-phenylphenonebenzophenone-3 (i.e. Benzophenone-3) or triazine compounds such as bis-ethylhexyloxyphenol methoxyphenyl triazine (ie betrazino) require solvents that keep these active substances in solution or emulsion and prevent crystallization. ...

Claims

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Application Information

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IPC IPC(8): A61K8/06A61K8/49A61Q19/00A61K8/35A61K8/44
CPCA61K8/445A61K8/40A61K2800/49A61Q17/04A61K8/35A61K8/4973A61K8/4966
Inventor P·坦纳B·芬利
Owner THE PROCTER & GAMBLE COMPANY
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