Medical image registration method based on combination of mutual information and gradient information

A gradient information, medical image technology, applied in the field of medical image processing, can solve the problem of low precision

CN103886586AActive Publication Date: 2014-06-25上海全景医学影像诊断中心有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2014-06-25

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Abstract

The invention provides a medical image registration method based on combination of mutual information and gradient information, comprising steps of performing weighting on mutual information similarity and adding difference values of a gradient model into gradient similarity, performing space changing on a floating image to be registered and calculating similarity measure of a reference image and the changed floating image. The invention provides a similarity measure function of weighting mutual information and gradient information. The similarity measure can attain a maximization value through constantly optimizing search and changing space, and the registration is successful. The similarity measure function is employed in the process of the registration, which can effectively solve the problems that the medical image registration algorism is low in accuracy and the robustness is not strong.
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Description

technical field

[0001] The invention relates to a medical image registration method based on the combination of mutual information and gradient information, in particular to a medical image registration method based on the combination of weighted normalized mutual information and gradient information, belonging to the field of medical image processing. Background technique

[0002] With the development of medicine, computer technology and bioengineering technology, medical imaging provides medical images of various modalities (CT, MRI, PET) for clinical diagnosis. In actual clinical applications, images of different modalities usually need to be Fusion together, get richer information in order to understand the comprehensive information of diseased tissues or organs, so as to make an accurate diagnosis or formulate an appropriate treatment plan. Image registration is an important prerequisite for image fusion. Image registration began in the 1990s. It refers to spatially cha...

Examples

Embodiment Construction

[0036] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0037] figure 1 is a framework diagram for medical image registration. First, image acquisition is carried out, and two devices are designed: imaging equipment and acquisition equipment. Medical imaging equipment includes CT, MRI, B-ultrasound, etc.; secondly, image preprocessing, including image denoising and image enhancement; and then the preprocessed image The image is registered, and the registration method based on the combination of weighted normalized mutual information and improved gradient information is adopted, and the registration can be output after successful registration. The present invention mainly makes corresponding improvements to the similarity measure of registration.

[0038] figure 2 It is a specific flowchart of medical image registration based on GWNMI. After preprocessing, space transform the floating ...