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Adaptive radiotherapy with spectral tissue of interest imaging and tracking

A radiation therapy, tissue technology, applied in radiation therapy, equipment for radiation diagnosis, treatment, etc.

Active Publication Date: 2014-11-05
KONINKLJIJKE PHILIPS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Unfortunately, implanting such beads in or near a patient's tissue of interest is an invasive and potentially challenging task

Method used

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  • Adaptive radiotherapy with spectral tissue of interest imaging and tracking
  • Adaptive radiotherapy with spectral tissue of interest imaging and tracking
  • Adaptive radiotherapy with spectral tissue of interest imaging and tracking

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Embodiment Construction

[0018] An adaptive radiation therapy approach is described below in which the spectral X-ray and / or spectral CT imaging capabilities of the radiation therapy device are configured to target gold and / or other k-edge material-doped nano-ions that are targeted to the region of interest in the patient. tissue, and optionally used to enhance a local dose of cells to said tissue of interest) imaging during a radiation therapy course of a patient to produce a contrast-enhanced spectral image of said tissue of interest. This may improve contrast enhancement of the tissue of interest relative to configurations in which such spectral imaging functionality is absent, which allows for improved tracking and targeting of the tissue of interest in adaptive radiation therapy without intervention in the patient Sex marker beads implanted.

[0019] figure 1 and figure 2 An exemplary radiotherapy apparatus 100 is schematically illustrated, including spectral imaging hardware and functionality...

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PUM

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Abstract

A radio therapy apparatus (100) includes a tissue of interest tracker (124) that receives a first image of tissue of interest and a second later acquired spectral image of the tissue of interest and tracks a change in a geometry and / or location of the tissue of interest based at least on the first and second images and generates a signal indicative of the change. The second image is generated based on a first spectral signal corresponding to an output of an energy-resolving radiation sensitive detector array for a first predetermined energy range and a second spectral signal corresponding to an output of the energy-resolving radiation sensitive detector array for a second predetermined energy range and visually enhances scanned structure corresponding to the first or second signals while visually suppressing scanned structure corresponding to the other of the first or second signals. An adaptive planner (126) updates a radiotherapy treatment plan based on the signal.

Description

technical field [0001] The following relates generally to adaptive radiation therapy, and more specifically to adaptive radiation therapy with spectral imaging and tracking of tissue of interest. Background technique [0002] Radiation therapy (also known as radiation oncology and radiation therapy) is a technique in which ionizing radiation is used to control or kill a tissue of interest, such as tumor cells, by damaging the DNA of the cells of the tissue of interest kick in. With radiation therapy, a patient typically receives a dose of ionizing radiation administered at regular intervals (eg, daily) over a period of time (eg, several weeks). During the treatment procedure, the patient is placed in the examination area of ​​a radiotherapy facility (commonly referred to as a linear accelerator or linear accelerator), which is used to irradiate the tumor. Radiation therapy planning typically defines a beam shape and several exposure angles that intersect at the tissue of i...

Claims

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Application Information

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IPC IPC(8): A61B6/00A61N5/10
CPCA61N5/1065A61B6/481A61B6/4241A61B19/50A61B6/482A61B2019/5265A61N2005/1061A61N5/1064A61B19/5244A61B2019/5466A61B6/4266A61B2019/5238A61B34/20A61B2090/376A61B34/10A61B2034/2065A61B2090/3966G06T7/74A61N2005/1098G06T7/0012G06T2207/10128G06T2207/30024
Inventor R·曼茨克C·O·斯基拉
Owner KONINKLJIJKE PHILIPS NV
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