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Puerarin injection and quality control method thereof

A technology of puerarin and injection, applied in the field of medicine, can solve problems such as fluctuation of test results

Active Publication Date: 2015-12-09
CHENGDU TIANTAISHAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the quality control of puerarin injection, the fluctuation of test results caused by unknown reasons still needs to be overcome

Method used

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  • Puerarin injection and quality control method thereof
  • Puerarin injection and quality control method thereof
  • Puerarin injection and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1: prepare puerarin injection

[0040] formula:

[0041] Puerarin 50mg,

[0042] Propylene glycol 500 mg,

[0043] Water for injection, appropriate amount, added to 1ml.

[0044] Preparation method: add puerarin to propylene glycol, add about 200mg of water, ultrasonically dissolve puerarin, add water to the full amount, and obtain. The pH of the obtained injection is determined to be in the range of 3.5-5.5.

Embodiment 2

[0045] Embodiment 2: preparation puerarin injection

[0046] formula:

[0047] Puerarin 25mg,

[0048] Propylene glycol 450mg,

[0049] Water for injection, appropriate amount, added to 1ml.

[0050] Preparation method: add puerarin to propylene glycol, add about 100mg of water, ultrasonically dissolve puerarin, add water to the full amount, and obtain. The pH of the obtained injection is determined to be in the range of 3.5-5.5.

Embodiment 3

[0051] Embodiment 3: preparation puerarin injection

[0052] formula:

[0053] Puerarin 25mg,

[0054] Propylene glycol 550mg,

[0055] Water for injection, appropriate amount, added to 1ml.

[0056] Preparation method: add puerarin to propylene glycol, add about 100mg of water, ultrasonically dissolve puerarin, add water to the full amount, and obtain. The pH of the obtained injection is determined to be in the range of 3.5-5.5.

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PUM

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Abstract

The invention relates to a puerarin injection and a quality control method thereof. 1Ml of the puerarin injection comprises 10-100mg of puerarin, 400-600mg of propylene glycol, and injection water added to an equilibrium volume. The method using HPLC to detect relevant substances in the puerarin injection has an excellent methodological performance.

Description

technical field [0001] The invention belongs to the technical field of medicine, relates to a puerarin injection, and also relates to a quality control method of the puerarin injection. The method of the invention can advantageously control the puerarin injection. Background technique [0002] Pueraria is a perennial leguminous twining vine, with many side vines and fibrous roots, but the roots are deep, spindle-shaped or long rod-shaped, and the skin is light yellow and wrinkled. It is the main edible and medicinal part. Pueraria lobata is the dried root of Pueraria Lobata (Willd.) Ohwi or P. thomsomi Benth. As a commonly used traditional Chinese medicine, kudzu root was first recorded in "Shen Nong's Materia Medica", and it was listed as a middle-grade product. It has been recorded in herbal medicines since the past dynasties. It is sweet, pungent, and flat in nature. Improve the body's immunity and other functions. At present, kudzu root is widely used in traditional Ch...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/352A61K47/10G01N30/88
Inventor 吴国庆张莲莲左伟余茹苟志君金春花赵东明
Owner CHENGDU TIANTAISHAN PHARMA
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