Handheld confocal skin microscopic method and handheld confocal skin microscopic device

A confocal, hand-held technology, used in measurement devices, material analysis by optical means, instruments, etc., can solve the problems of image disorder, unfavorable observation and imaging speed, limited clarity, etc., to eliminate vibration and conjugation. the effect of

Active Publication Date: 2016-03-23
GUANGDONG OPTO MEDIC TECH CO LTD
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Problems solved by technology

[0005] The purpose of the present invention is to provide a hand-held confocal skin microscopy method and device, aiming to solve the problem of limited definition of existing hand-held confocal microscopes, disordered images, unfavorable observation and slow imaging speed, and image blurring due to shaking. blurry problem

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  • Handheld confocal skin microscopic method and handheld confocal skin microscopic device
  • Handheld confocal skin microscopic method and handheld confocal skin microscopic device
  • Handheld confocal skin microscopic method and handheld confocal skin microscopic device

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[0047] In order to make the object, technical solution and advantages of the present invention more clear and definite, the present invention will be further described in detail below with reference to the accompanying drawings and examples.

[0048] like figure 1 and figure 2 As shown, a hand-held confocal skin microscopy device can realize confocal in-body tomography microscopy imaging, and at the same time effectively avoid the vibration caused by the hand-held operation, which will affect the conjugate relationship between the point light source and the detection filter pinhole. include:

[0049] A light source and a detection module 100 that provide the excitation light beam and detect the return signal light for the entire device;

[0050] A hand-held mobile confocal scanning module 200 that focuses the excitation beam provided by the light source and the detection module 100 to form a two-dimensional scanning spot on the focal plane, and simultaneously collects the s...

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Abstract

The invention discloses a handheld confocal skin microscopic method and a handheld confocal skin microscopic device. The device includes: a light source and detection module being connected to an optical signal through a single-mode fiber, and a handheld movable confocal scanning module. A control device is connected to the light source and detection module and the handheld movable confocal scanning module. In the device, a confocal light path is modularized and includes the light source and detection module, which is used for providing an excited light beam for the system and detecting feedback signal light, and the handheld movable confocal scanning module, which is used for focusing the excited light beam to form a two-dimensional scanning light spot on a focused plane and collecting the feedback signal light of a sample. The two modules are connected to each other through the single-mode fiber. With the handheld movable confocal scanning module, real-time in-vivo confocal microscopic imaging can be flexibly achieved. The single-mode fiber, as a point light source and a detection wave filtering pinhole of the handheld movable confocal scanning module, achieves constant conjugation of the point light source and the detection wave filtering pinhole, thereby eliminating influence on conjugation due to vibration during a use process.

Description

technical field [0001] The invention relates to a microscopic device, in particular to a hand-held confocal skin microscopic method and device. Background technique [0002] Confocal microscopy was first proposed by M.Minsky in 1957. Its purpose is to eliminate the influence of scattered light when ordinary optical microscopes detect samples. Since then, confocal microscopy has been widely used due to its excellent three-dimensional tomographic capabilities and high resolution. Since the optical path of the confocal microscope needs to include lasers, detectors, scanning galvanometer systems or nano-translation stages and other instruments with a certain volume and weight, it is not easy to achieve portability or mobility; moreover, in order to ensure the imaging quality of the confocal microscope, The positions of the point light source and the detection filter pinhole require a high degree of conjugation, and the vibration caused by the moving confocal microscope will aff...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/01G01N21/64
CPCG01N21/01G01N21/6402
Inventor 顾兆泰赵晖王翰林安昕张浠
Owner GUANGDONG OPTO MEDIC TECH CO LTD
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