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Vaccine against porcine circo virus type 2

一种猪圆环病毒、疫苗的技术，应用在抗病毒剂、疫苗、病毒等方向，能够解决没有显示出、长免疫期等问题

Inactive Publication Date: 2016-08-10
INTERVET INT BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

None of them showed a longer duration of immunity than commercially available vaccines as known

Method used

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  • Vaccine against porcine circo virus type 2
  • Vaccine against porcine circo virus type 2
  • Vaccine against porcine circo virus type 2

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1 is an experiment showing that a single dose of intradermal vaccination can provide 23 week immunity against porcine circovirus type 2 infection.

Embodiment 2

[0040] Example 2 is another experiment where a single vaccination regimen with PCV2 ID showed that vaccination was safe and resulted in protective titers.

Embodiment 3

[0041] Example 3 is a direct comparison between intradermal and intramuscular vaccination.

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PUM

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Abstract

The present invention pertains to a vaccine comprising a non-replicating immunogen of porcine circo virus type 2 for use in prophylactically treating an animal that has circulating antibodies directed against porcine circo virus type 2, against an infection with pathogenic porcine circo virus type 2 by a single dose administration of the vaccine into the dermis of the animal.

Description

field of invention [0001] The present invention relates to a vaccine against porcine circovirus type 2 (PCV-2) and methods of using the vaccine to protect animals against this infection. Background technique [0002] PCV-2 is associated with post-weaning multisystemic wasting syndrome (PMWS) observed in young pigs. The disease first appeared in Canada in 1991. The clinical symptoms and pathology were published in 1996 and included progressive emaciation, dyspnea, shortness of breath, and occasionally icterus and jaundice. [0003] Nayar et al., Can.Vet.J.Volum 38, June 1997 detected porcine circovirus in pigs with clinical signs of PMWS and concluded that, in addition to known PCV recognized as a natural resident of PK-15 cells In addition to those, PCV may also be associated with PMWS. Later publications (Hamel et al., J.Virol., 72(6), 5262-5267, 1998; Meehan et al., J.gen.Virol., 79, 2171-2179, 1998) confirmed these results, and A new pathogenic PCV was proposed (Meeha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/02A61K39/12A61P31/20A61P31/04
CPCA61K39/0241A61K39/105A61K2039/54A61K2039/552A61K2039/55566A61K2039/70C12N2750/10034A61K39/12A61P31/04A61P31/12A61P31/20A61P37/04C12N7/00
Inventor V·发钦格M·斯诺M·H·维特韦里伊特
Owner INTERVET INT BV
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