Composition of oily, pungent and odoriferous substances and process of preparation thereof
一种组合物、有气味的技术,应用在含有油性的,能够解决延长活性成分释放、延迟、降低有效成分辛辣和刺激特性等问题
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[0145] The pepper compositions of Examples 1, 2, 3 and 4 were subjected to accelerated stability studies at 40±2°C / 75±5% relative humidity (RH) according to ICH guidelines. The results of this study are as follows,
[0146]
[0147] in conclusion:
[0148] Stability data for 3 months at 40°C and 75% relative humidity were found to be satisfactory for assay and dissolution.
[0149] dissolve data
[0150]
[0151] in conclusion:
[0152] Dissolution studies did not show any release in 0.1 N hydrochloric acid within 2 hours, and capsaicin was completely released over a 6 hour time period in pH 7.4 phosphate buffer with sodium lauryl sulfate.
[0153] Advantages of the invention
[0154] 1. Provide free-flowing, non-sticky solid compositions of oily, pungent, pungent, odorous active substances, wherein the inherent nutritional and biological benefits of said active substances are maintained at high concentrations, But without the discomfort associated with the active s...
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