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Transparent photoelectrode of multiple recording spots based on fibers

A multi-recording and photoelectrode technology, which is applied in the direction of optical waveguide and light guide, can solve the problems of not playing a functional role, and achieve the effect of solving the limitation of recording points, solving the difficulty of implanting flexible electrodes, and good repeatability

Inactive Publication Date: 2017-01-04
INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI
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  • Abstract
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  • Claims
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Problems solved by technology

At present, hard materials are used to assist implantation, and the materials are removed after implantation, so that the auxiliary implantation part does not play a functional role

Method used

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  • Transparent photoelectrode of multiple recording spots based on fibers
  • Transparent photoelectrode of multiple recording spots based on fibers
  • Transparent photoelectrode of multiple recording spots based on fibers

Examples

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Embodiment Construction

[0023] see Figure 1-Figure 3 As shown, the present invention provides a kind of optical fiber-based transparent photoelectrode structure with multiple recording points, comprising:

[0024] A multimode optical fiber 1, the multimode optical fiber 1 includes a core 11, a cladding 12 and a protective layer 13, the core 11 of the multimode optical fiber 1 is tapered, and the protective layer 13 is removed. The cone-shaped structure is beneficial to reduce the damage of electrode implantation, ensure the survival rate of cells near the electrode recording point, and enable the electrode to achieve effective stimulation and recording;

[0025] A flexible electrode 2, with a small hole 23 in the middle of the flexible electrode 2, the small hole 23 of the flexible electrode 2 is aligned with the core 11 of the multimode optical fiber 1, and wraps the multimode optical fiber 1, and the flexible electrode 2 is strip-shaped , is a left-right symmetrical structure, the small hole 23 i...

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Abstract

A transparent photoelectrode of multiple recording spots based on fibers comprises: a multi-mode fiber which includes a fiber core, cladding and a protective layer; and a flexible electrode which has a small hole at the middle portion of the flexible electrode, wherein the small hole of the flexible electrode is aligned to the fiber core of the multi-mode fiber and wraps the multi-mode fiber. The structure formed by the invention solves the problem that the current photostimulation position and the recording spots are non-synchronous, and solves the problems of the restriction of the fiber electrode recording spots and the difficult implantation of the flexible electrode. The transparent photoelectrode of multiple recording spots based on fibers has the characteristics of the stimulation precision with high photostimulation and good biocompatibility of the flexible electrode which can perform long-term record.

Description

technical field [0001] The invention relates to related technical fields such as microprocessing technology, optical fiber communication, and biological signal detection, and in particular to an optical fiber-based transparent photoelectrode with multiple recording points. Background technique [0002] Electrodes are an important means of obtaining nerve electrical signals for neuroelectrophysiology, neurological disease treatment, and brain science research. The electrodes record neuronal firing and also stimulate the electrical activity that affects neurons. At present, there are electrical stimulation and light stimulation. Light stimulation is based on optogenetics biotechnology. Compared with electrical stimulation, it has higher spatial resolution and can perform electrical recording at the same time as stimulation. At present, the most commonly used photoelectrode structure is to adhere the metal wire to the optical fiber. The electrode structure is simple, but the d...

Claims

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Application Information

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IPC IPC(8): G02B6/12
CPCG02B6/12
Inventor 裴为华解宇星邢潇陈弘达
Owner INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI
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