An analgesic and anti-inflammatory pharmaceutical composition and its preparation method and application
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Analgesic and anti-inflammatory composition technology, applied in the field of analgesic and anti-inflammatory pharmaceutical composition and its preparation
Active Publication Date: 2022-05-17
辽宁华润本溪三药有限公司 +1
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[0004] However, at present, there is no report about the composition of saikosaponin D, paeoniflorin, corydalin and ammonium glycyrrhizinate for analgesic and anti-inflammatory
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Embodiment 1
[0023] The raw material composition of the analgesic and anti-inflammatory pharmaceutical composition of this example is: saikosaponin D 186.6g, paeoniflorin 138.1g, corydalin 75.2g, ammonium glycyrrhizinate 54.3g;
[0024] The preparation method of the pharmaceutical composition comprises the following steps: respectively taking selected weights of saikosaponin D, paeoniflorin, corydalin and ammonium glycyrrhizinate, and mixing them uniformly to obtain the product.
[0025] The analgesic and anti-inflammatory pharmaceutical composition of this example is prepared into granules by adding conventional excipients and following conventional techniques.
Embodiment 2
[0027] The raw material composition of the analgesic and anti-inflammatory pharmaceutical composition of this embodiment is: saikosaponin D 170g, paeoniflorin 152g, corydalin 68g, ammonium glycyrrhizinate 60g;
[0028] The preparation method of the pharmaceutical composition comprises the following steps: respectively taking selected weights of saikosaponin D, paeoniflorin, corydalin and ammonium glycyrrhizinate, and mixing them uniformly to obtain the product.
[0029] The analgesic and anti-inflammatory pharmaceutical composition of this example is made into a honeyed pill by adding conventional excipients and following a conventional process.
Embodiment 3
[0031] The raw material composition of the analgesic and anti-inflammatory pharmaceutical composition of this embodiment is: saikosaponin D 205g, paeoniflorin 125g, corydalin 82g, ammonium glycyrrhizinate 50g;
[0032] The preparation method of the pharmaceutical composition comprises the following steps: respectively taking selected weights of saikosaponin D, paeoniflorin, corydalin and ammonium glycyrrhizinate, and mixing them uniformly to obtain the product.
[0033] The analgesic and anti-inflammatory pharmaceutical composition of this example is prepared into a powder by adding conventional excipients and following a conventional process.
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Abstract
The invention specifically relates to an analgesic and anti-inflammatory pharmaceutical composition, a preparation method and application thereof. The pharmaceutical composition comprises the following raw materials: 155-220 parts by weight of saikosaponin D, 110-168 parts by weight of paeoniflorin, 60-90 parts by weight of corydalin, and 45-65 parts by weight of ammonium glycyrrhizinate. The pharmaceutical composition of the present invention uses saikosaponin D, paeoniflorin, corydalin and ammonium glycyrrhizinate as raw materials, and each raw material cooperates with each other and acts together under a specific ratio, and has a significant analgesic and anti-inflammatory effect; the drug The composition has significant analgesic and anti-inflammatory effects, and its analgesic and anti-inflammatory effects are superior to those of any three of the four raw materials, and are also superior to the analgesic and anti-inflammatory effects of the four raw materials alone. The composition has a synergistic effect.
Description
technical field [0001] The invention belongs to the field of medicines or health care products, and in particular relates to an analgesic and anti-inflammatory pharmaceutical composition, a preparation method and application thereof. Background technique [0002] Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of antipyretic and analgesic drugs widely used clinically. Since people extracted acetylsalicylic acid (aspirin) from willow bark to reduce fever, new members have been added to the non-steroidal family, and non-steroidal anti-inflammatory drugs have gradually become one of the most common drugs prescribed in the world. The antipyretic, analgesic, anti-inflammatory and anti-rheumatic effects have been verified in many years of clinical practice. [0003] More and more studies have shown that natural medicine extracts and their derivatives have significant analgesic and anti-inflammatory effects, the representative ones are as follows: According to literatur...
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